Publications

All my published work in mathematics can be found on this website under math work.

Over the years of my employment in Compugen I have been involved in the computational side of several biological projects. Examining the list of published papers with me as co-author, using PubMed for example, shows the wide range of applications of mathematics and statistics in biology and medicine.

In most cases these projects involved the work of many people. This is especially true in the more biologically oriented papers (4-6). My involvement is restricted to the computational predictive stage, and in rare occasions statistical analysis of experimental results.

8: Krintel SB, Essioux L, Wool A, Johansen JS, Schreiber E, Zekharya T, Akiva P, Ostergaard M, Hetland ML.

CD6 and Syntaxin Binding Protein 6 Variants and Response to Tumor Necrosis Factor Alpha Inhibitors in Danish Patients with Rheumatoid Arthritis.

PLoS One. 2012;7(6):e38539. Epub 2012 Jun 7. PMID:22685579

7: Pini A, Shemesh R, Samuel CS, Bathgate RA, Zauberman A, Hermesh C, Wool A, Bani D, Rotman G.

Prevention of bleomycin-induced pulmonary fibrosis by a novel antifibrotic peptide with relaxin-like activity.

J Pharmacol Exp Ther. 2010 Dec;335(3):589-99. Epub 2010 Sep 8. PMID: 20826567

6: Kliger Y, Levy O, Oren A, Ashkenazy H, Tiran Z, Novik A, Rosenberg A, Amir A,

Wool A, Toporik A, Schreiber E, Eshel D, Levine Z, Cohen Y, Nold-Petry C,

Dinarello CA, Borukhov I. Peptides modulating conformational changes in secreted

chaperones: from in silico design to preclinical proof of concept. Proc Natl Acad

Sci U S A. 2009 Aug 18;106(33):13797-801. Epub 2009 Aug 5. PubMed PMID: 19666568;

PubMed Central PMCID: PMC2728974.

5: Shemesh R, Hermesh C, Toporik A, Levine Z, Novik A, Wool A, Kliger Y,

Rosenberg A, Bathgate RA, Cohen Y. Activation of relaxin-related receptors by

short, linear peptides derived from a collagen-containing precursor. Ann N Y Acad

Sci. 2009 Apr;1160:78-86. PubMed PMID: 19416163.

4: Shemesh R, Toporik A, Levine Z, Hecht I, Rotman G, Wool A, Dahary D, Gofer E,

Kliger Y, Soffer MA, Rosenberg A, Eshel D, Cohen Y. Discovery and validation of

novel peptide agonists for G-protein-coupled receptors. J Biol Chem. 2008 Dec

12;283(50):34643-9. Epub 2008 Oct 9. PubMed PMID: 18854305.

3: Kliger Y, Gofer E, Wool A, Toporik A, Apatoff A, Olshansky M. Predicting

proteolytic sites in extracellular proteins: only halfway there. Bioinformatics.

2008 Apr 15;24(8):1049-55. Epub 2008 Mar 4. PubMed PMID: 18321887.

2: Havilio M, Wool A. Large-scale unrestricted identification of post-translation

modifications using tandem mass spectrometry. Anal Chem. 2007 Feb

15;79(4):1362-8. PubMed PMID: 17297935.

1: Wool A, Smilansky Z. Precalibration of matrix-assisted laser

desorption/ionization-time of flight spectra for peptide mass fingerprinting.

Proteomics. 2002 Oct;2(10):1365-73. PubMed PMID: 12422354.