Magnetic resonance imaging/ Inventor
.In 1977, a doctor named Raymond Damadian invented the first Magnetic Resonance Imaging (MRI). Because of his seven years of hard work in the creation of this sophisticated machine, the machine was given the name Indomitable. He used the "sensitive point" method for NMR signals. It is because of the saddle-shaped magnetic field where only a small volume in the center corresponds to the resonant frequency of the RF pulse. On July 2, 1977, one of Damadian's assistants, Larry Minkoff, was inside the MRI to try to access the equipment and undergo an initial scan. A few years after his first invention, Damadian founded the FONAR Corporation, which launched the first commercial MRI scanner, and successfully obtained a patent for his machine design.
His deep scientific interest and passion led him to create the most sophisticated machines used in the twenty-first century. Raymond Damadian died on August 3, 2022, at the age of 86. Since then, its MRI machine is increasingly being introduced by medical experts in any Hospital to carry out the scanning process
Raymond Damadian, Father of the MRI
Assistant Larry Minkoff in Indomitable
Damadian’s National Medal of Technology, 1988.
Damadian's patent application
First whole body image (Minkoff's chest), obtained July, 1977. It required nearly 5 hours to produce.
President Ronald Reagan presents the National Medal of Technology to Damadian, 1988.
American physicist
MRI was originally called nuclear magnetic resonance (NMR) by a physicist from Cornell University, Isidor Isaac Rabi. The eldest of these 2 siblings was born in Rymanov, Austria on July 29, 1898 and when he was 7 years old he immigrated to New York City. His first success was as an electrical engineering student, but a few years later, he changed his major to physics and was awarded a PhD degree for his thesis on the measurement of the magnetic properties of crystals. Rabi's next breakthrough came when he became an author in scientific articles covering the fields of magnetism, quantum mechanics and nuclear physics.
Nuclear Magnetic Resonance (NMR) was first reported in 1939 by Isidor Rabi, who isolated individual nuclei from each other using molecular beams in a vacuum. In 1944, he was awarded the Nobel Prize for his success in creating the atomic and molecular beam magnetic resonance technique. It is possible to determine mechanical and magnetic properties using various Rabi magnetic methods. Rabi died in New York City on January 11, 1988, at the age of 89. A few years after receiving the Nobel prize, scientists Felix Bloch and Edward Purcell independently developed a new method that developed NMR from liquids to solids.
American chemist
Paul C. Lauterbur
A physician and fellow Damadian, Paul C. Lauterbur is a faculty member and pioneer in the field of image development. By establishing nuclear resonance in the study of molecules, liquids, and solids, he contributed to the notion behind the invention of magnetic resonance imaging (MRI). He continued the work of Isidor Rabi in 1973 by creating a technique for the first 2-D images from NMR signals. Professor Lauterbur first learned to use NMR while working at Dow Corning Mellon Institutional Laboratories prior to the use of his invention. He was the first researcher to use NMR to create images, which completely changed the field of medicine. But until he left Brooke University in 1985, his ideas were only seen as commonplace by those in his immediate vicinity.
After one of the diagnostic imaging techniques and 40 million scans were conducted, the development of MRI continued. Following the successful development of MRI technology in the Chemistry Department of Stony Brook University, he was shared with another researcher Sir Peter Mansfield from the University of Nottingham in England to receive the 2003 Nobel Prize in Physiology or Medicine.
Sir Peter Mansfield and Paul Lauterbur, Winners of the Nobel Prize for Medicine, 2003
Paul C. Lauterbur receiving his Nobel Prize from His Majesty King Carl XVI Gustaf of Sweden at the Stockholm Concert Hall, 10 December 2003
Paul C. Lauterbur and Sir Peter Mansfield at the Nobel Prize Award Ceremony at the Stockholm Concert Hall
Felix Bloch & Edward Purcell
Magnetic Resonance Imaging (MRI) is a type of scan that uses high-frequency radio waves and a strong magnetic field to produce detailed images of the inside of the body. The patient undergoing MRI has to lie in the tube while the scan is carried out without moving the body. This is because it may be difficult to get a clear image if the patient moves a lot. It is also a painless test because it uses good technologyMRI does not use X-rays, it is a test to get the results of diagnosis or treatment monitoring especially in the part of the patient's brain.
When Isidor Rabi invented nuclear magnetic resonance imaging (NMRI), it was known by that name at first. However, this term was changed to MRI when it was discovered that the word "nuclear" was associated with radioactivity and nuclear bombs, which caused some people to have a negative opinion about it. On the other hand, it is a technology that is free from radioactivity and ionizing radiation. Strong magnetic fields are used in NMR, which can be dangerous to people's health if they have a heart attack. As a result, they are not allowed to be too close to the MRI imager. In addition, patients undergoing scanning are not allowed to bring in any iron-related equipment as it may cause unwanted consequences.
There are two main types of MRI machines, open and closed bore. A closed-bore MRI will capture images in high quality, while an open-bore MRI may provide more comfort to the patient while the scan is in progress due to less closed spaceOver the years, MRI has become an indispensable medical imaging device because it can obtain other physiological information. MRI needs performance improvements related to system hardware, including the main magnet, gradient coil and radio frequency (RF) coil.
1) MAIN MAGNET
This main magnet uses a large amount of ferromagnetic shielding which makes it heavy and relatively large system size with high installation cost. For information, superconductor magnets are made of multiple solenoid coils and insulated coils. It is a highly magnetic combination using a combination of an iron core and a superconductor coil. The cryogenic system is used to keep the superconductor wire in a safe condition.
The MRI has been specially designed including a 0.7T whole body plane, a 1.5T whole body cylinder, a 7.0T animal MRI system and a 9.41T whole cylinder.
Because open MRI has advantages, it can be used using interventions. The shape of the magnetic field depends on the Yoke and Pole, and the magnetic source coi.
It is an essential component of standard MRI scanning that produces a linear gradient magnetic field superimposed on a strong uniform magnetic field. The gradient of the magnetic field produced by the gradient coil is desired to be as linear as possible. It is especially important in high-field and fast imaging when all coil parameters must be highly optimized.
There are three types of gradient coils which are x,y and z coils. The red and blue colors show the current flowing clockwise and counterclockwise. Three axes are fixed by epoxy resin in an encapsulated assembly.
There is also a cooling device and Shim tray installed. Part of the resin prevents the vibration of the gradient coil which prevents twisting and deformation under the strong Lorentz force.
4) RF Coil
The RF coil is a key component of the MRI system that functions as a transmitter and receiver in the final image formation.
There are many types of coils that can be classified, but all coils can basically be considered as two types of coils which are surface and volume. A common surface coil is used as a receiver, this is because the field it produces is not homogeneous and will be detrimental to the imaging
Volumetric coils may be used in ultra-high fields. It can be realized through circuit types such as coaxial lines, strip lines, microstrips or waveguides. A volume coil can be thought of as a toroidal arrangement of many transmission line elements
Health care provision can be evaluated through several structures in the body using MRI including the brain, nervous tissue, heart, bile ducts and all internal organs.Most of the human body has water molecules made up of hydrogen and oxygen
In every atom there are smaller particles called protons and they are very sensitive to magnetic fields. So when the patient lies under the scanner's magnet, the protons will also go in the same direction.It also helps to distinguish between different types of tissue in the body because protons in different types of tissue realign at different speeds.
the entire exam usually takes 30 to 50 minutes to complete. Your healthcare provider will be able to give you a more exact time range based on the specific reason for your scan.
REFERENCES
www.nobelprize.org/prizes/medicine/2003/lauterbur/facts/
8www.intechopen.com/chapters/69058
my.clevelandclinic.org/health/diagnostics/4876-magnetic-resonance-imaging-mri
www.gehealthcare.com/insights/article/when-and-why-was-mri-invented
lemelson.mit.edu/award-winners/raymond-damadian
www.nhs.uk/conditions/mri-scan/
mri-q.com/who-invented-mri.html