The topics below cover Integrity issues that you might encounter, and some tips on how to address them. If you suspect any of such or similar issues, please contact the editor in chief immediately.
Many resources and text on this page are directly from or based on resources provided by COPE (Committee on Publication Ethics)
Link to Guidelines for detecting LLM text
Authors must declare any use of AI tools in their data collection, data analysis, writing, and editing process, including the use of LLM tools such as ChatGPT.
Authors under-report AI use (study presented at Peer Review Congress Presentation 2025, preprint)
sounds too perfect
neutral or overly balanced tone
lacks a real voice or emotion
no grammatical, mechanical, or idiomatic errors; no idiosyncratic phrases
lacks depth, precision, and cohesion
only sounds compelling when read superficially, but arguments do not hold up under scrutiny
lacks coherence across sentences and sections (semantic inconsistencies, logical errors) (Uchendu et al. 2023)
repeats the same idea without developing it further
use general terms instead of effectively tailored information relevant to the specific problem context
frequently commit factual and common-sense reasoning errors, which are easily noticed by humans (Jawahar, Abdul-Mageed, and Lakshmanan 2020)
verbose yet generic
nothing new: reads stylish and smooth, but fails to provide fresh insights or a clear main message upon closer reading (Ma et al. 2023)
not really relevant: loads of text touches on the topic, but appears irrelevant upon closer reading (Dugan et al. 2023)
uses filler phrases and meta dialogue (talks about the issue without ever getting to the issue)
describes and talks about the topic in a superficial way without sufficient detail and nuance, and without ever taking a stance on the topic; in contrast, human authors often write lengthy paragraphs that weighs arguments (Desaire et al. 2023), using terms such as “but,” “however,” and “although.”
uses loads of adjectives and bloated descriptors that can be omitted without loss of meaning
nonsensical jargon
uses nonsensical paraphrases terms for technical jargon (see article with examples)
'chest growth' instead of 'breast tumor', 'flat variable' instead of 'categorical variable'
fabricated content, including fabricated references
LLM-generated and -edited text often contains factual errors, including fabricated data and fabricated citations (see section of 'fabricated citations').
This list has been constructed based on an article by Wu, Junchao, et al. "A survey on llm-generated text detection: Necessity, methods, and future directions." Computational Linguistics 51.1 (2025): 275-338.
Resources
LLM text detection methods - a review by Wu et al. (2025) - citation: Wu, Junchao, et al. "A survey on llm-generated text detection: Necessity, methods, and future directions." Computational Linguistics 51.1 (2025): 275-338.
The Scholarly Kitchen about a taxonomy for describing use of GenAI in articles (GAIDeT)
How to detect LLM generated text (published by the Association for Computing Machinery)
Recommended action
If there is strong evidence that the manuscript was written using LLM tools yet authors did not disclose the use of LLM, please contact the editor in chief and the managing editor about your concern.
What will happen next:
The editor will contact the author about their possible use of GenAI tools and request that the authors disclose any such use using the GAIDeT tool (see Scholarly Kitchen article linked in the Resources of this section).
The editor will invite a report by one of ICB's publication integrity reviewers.
The editor's decision letter will point out areas where the writing needs to be revised to enhance clarity (see list of LLM indicators)
Link to decision flowchart on inappropriate image manipulation
Authors must declare any use of AI tools in their data collection, data analysis, writing, and editing process, including the use of tools to enhance and manipulate images.
Authors under-report AI use, and image manipulation is becoming a major concern for publication integrity (study presented at Peer Review Congress Presentation 2025, article)
The most commonly affected images are Western blots and microscope images of stained cells or tissue (see resources in this section).
Resources
Cardenuto, João Phillipe, Daniel Moreira, and Anderson Rocha. "Strengthening Scientific Integrity: Digital Forensics for Biomedical Research Imaging." Conference on Graphics, Patterns and Images (SIBGRAPI). SBC, 2025. DOI: https://doi.org/10.5753/sibgrapi.est.2025.38268
see also ICB editor webpage on Research Integrity with a section on data integrity
Recommended action
If there is strong evidence that the manuscript contains figures that were generated or editing using GenAI tools yet authors did not disclose their use, please contact the editor in chief and the managing editor about your concern.
What will happen next:
The editor will contact the author about their possible use of GenAI tools and request that the authors disclose any such use using the GAIDeT tool (see Scholarly Kitchen article linked in the Resources of this section).
The editor will invite a report by one of ICB's publication integrity reviewers.
The editor's decision letter will point out areas where the writing needs to be revised to ensure scientific integrity.
Image manipulation that violate publication ethics will result in the rejection of the manuscript.
The editor will inform the author's institution, where necessary.
What is citation fabrication?
Citation fabrication can occur when authors use genAI tools such as ChatGPT to generate or edit their references.
Fabrications by genAI tools are sometimes called hallucinations, use of this term is discouraged because it anthropomorphizes these tools.
Where does it occur in the manuscript?
Fabricated citations can occur in the main text of the manuscript and the Reference list.
What does it look like?
Fabricated citations run the full spectrum from small omissions and addition (missing or added author name) and changes (slight deviations in the wording of the article title or journal name) over combining elements from multiple existing citations (title, author list and/or journal from different real references) to whole-cloth fabrications of journals, titles, and authors.
Some bibliographic resources have become infected by fabricated articles.
Recommended action
If you suspect that the manuscript contains fabricated references, immediately contact the editor in chief and the managing editor about your concern.
What will happen next:
Initial steps, the journal will ask the reviewer for evidence and investigating the concerns.
The editor will invite a report by one of ICB's publication integrity reviewers.
The editor will then contact the authors to discuss concerns about citation fabrication, allowing them an opportunity to respond or clarify before proceeding with any formal actions or decisions.
Potential actions based on the journal’s findings include notifying relevant parties, rejecting the manuscript, or reporting to the authors’ institutions, depending on the severity of the misconduct identified.
ICB does not allow peer reviewers to use GenAI tools to perform peer reviews. In particular, it is a breach of confidentiality to enter any part of a submitted manuscript, including peer reviews, into a LLM. Peer reviewers may use editing tools such as Grammarly to edit their reviews.
What does it look like?
Please refer to the section on LLM-generated and -edit manuscript for tips on how to spot LLM text.
Resources
Case study - Editor suspects LLM-generated peer review
see also ICB editor webpage on Peer Review
Recommended action
If you suspect that a peer review contains LLM text, immediately contact the editor in chief and the managing editor about your concern.
What will happen next:
The editor will reach out to the whistle blower to inquire about the possible misconduct.
If there is evidence for misconduct, the managing editor will rescind the invitation to review and will invite another peer reviewer.
The editor will contact the reviewer in cases of clear peer review misconduct, explaining the journal’s process and next steps.
The editor will inform the reviewer's institution, where necessary.
Visit COPE (Committee on Publication Ethics) for more information
Contact the editor in chief and managing editor