Publications
Publications
From the Lahiri lab:
Stevenson SR, Tzokov SB, Lahiri I, Ayscough KR, Bullough PA. (2025) Cryo-EM reconstruction of yeast ADP-actin filament at 2.5 Å resolution. A comparison with vertibrate F-actin. Structure. S0969-2126(24)00543-4.
Kumari A, Yadav A, Lahiri I. (2022) Transient state kinetics of Plasmodium falciparum apicoplast DNA polymerase suggests the involvement of accessory factors for efficient and accurate DNA synthesis. Biochemistry. 61(21):2319-33.
Mondal AK, Sengupta N, Singh M, Biswas R, Lata K, Lahiri I, Dutta S, Chattopadhyay K. (2022) Glu289 residue in the pore-forming motif of Vibrio cholerae cytolysin is important for efficient β-barrel pore formation. J Biol Chem. 298(10):102441-56.
Fagan SP, Mukherjee P, Jaremko JJ, Nelson-Rigg R, Wilson RC, Dangerfield T, Johnson KA, Lahiri I#, Pata JD#. (2021) Pyrophosphate release acts as a checkpoint during high fidelity DNA replication by the Staphylococcus aureus replicative DNA polymerase PolC. Nucleic Acids Res. 49(14):8324-38.
From Indro's postdoc:
Gillies JP*, Reimer JM*, Krasmanis E*, Lahiri I, Htet ZM, Leschziner AE#, Reck-Peterson SL#. (2022) Structural basis for cytoplasmic dynein-1 regulation by Lis1. eLife. 11:e71229.
Sharon I J, Haque AS, Grogg M, Lahiri I, Leschziner AE, Hilvert D, Schmeing MT. (2021) Structures and functions of cyan-physic synthetase, a common amino acid polymerase. Nature Chem Biol. 17(10):1101-10.
Deniston CA*, Salogiannis J*, Mathea S*, Snead D, Lahiri I, Donosa O, Watanabe R, Bohning J, Shiau A, Knapp S, Villa E, Reck-Peterson SL#, Leschziner AE#. (2020) Parkinson’s Disease-linked LRRK2 structure and model for microtubule interaction. Nature. 588(7837):344-49.
Lahiri I, Xu J, Han BG*, Oh J*, Wang D, DiMaio F, Leschziner AE. (2019) 3.1Å structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids. J Struct Biol. 207(3):270-78.
Cianfrocco MA#, Lahiri I, DiMaio F, Leschziner AE#. (2018) cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud. J Struct Biol. 203(3):230-35.
Xu J*, Lahiri I*, Wang W, Wier A, Cianfrocco MA, Chong J, Hare A, Dervan PB, DiMaio F, Leschziner AE#, Wang D#. (2017) Structural Basis for Eukaryotic Transcription-Coupled DNA Repair Initiation. Nature. 551(7682):653-57.
From Indro's PhD:
Mukherjee P*, Wilson RC*, Lahiri I, Pata JD. (2014) Three residues of the interdomain linker determine the conformation and single-base deletion fidelity of Y-family translesion polymerases. J Biol Chem. 289(10):6323
Lahiri I*, Mukherjee P*, Pata JD. (2013) Kinetic Characterization of Exonuclease-Deficient Staphylococcus aureus PolC, a C-family Replicative DNA Polymerase. PLoS ONE. 8(5): e63489.
Mukherjee P*, Lahiri I*, Pata JD. (2013) Human polymerase kappa uses a template-slippage deletion mechanism, but can realign the slipped strands to favour base substitution mutations over deletions. Nucleic Acids Res. 41(9):5024-35.
* Equal contribution author # Co-corresponding author