Wednesday 2/4

Essential Understanding- 6.1 DNA and RNA Structure

DNA and RNA REVIEW

1. Create Plates

2. The Discovery of the Stru2cture of DNA Clip (2 min)

3. Rosalind Franklin: She's Worth Another Look (pdf)

• • • go on a tangent for 5 min and find something interesting about her life that was not discussed in this article

    • Rosalind Franklin vs. Watson & Crick - Science History Rap Battle

4. VIDEO: Topic 6.1: DNA & RNA Structure (video worksheet) print (12 min)

5. Purines and Pyrimidines Bonding and Structural Differences

• Purines (Guanine and Adenine) 2 Ring Structures

• Pyrimidines (Thymine, Uracil and Cytosine) 1 Ring Structure

6. So How is Bacteria Different?

• • Bacterial Genetics Clip (4 min)- video worksheet (print) 

7. Plate E.Coli (if its here, crossing fingers!)

HWK) Complete: Transformation Lab Scenarios (s9-s16) and Start Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due 2/6)

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Thursday 2/5 

1. Transformation Lab bead part

2. Take Progress Check 6.1

• After you finish the progress check, check this out:

  • DNA Interactive (spend a few minutes checking this out) 

Essential Understanding- 6.2 Replication

5) 6.2 Lecture Video (16 min) (Video Notes) (15 min)

6) Topoisomerase Activity- Rope; Clay

• video 1 (2 min) and video 2 (2 min)

• DNA Topology (8 min)- DO NOT TAKE NOTES

HWK: Finish Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due  tomorrow)

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Friday 2/6

Turn in Chapter 16 Book Work

1. Plate E.Coli

2. The End Replication Problem! Solution: Telomerase! Watch this video Telomere Replication (2 min)

• Cell Senescence Video (video worksheet) print (10 min) 

• Aging Discussion

3. Take 6.2 Progress Check 

Essential Understanding- 6.3 Transcription and RNA Processing

4. Topic 6.3: Transcription & RNA Processing (17 min) (Video Notes)

5. Exons, Introns, Poly A Tail, GTP Cap explained concisely (5 min)

6. Gene Expression-Transcription POGIL (key)

7. Take 6.3 Progress Check

• (6.1, 6.2 and 6.3 Quiz Tuesday) 

Homework: Gene Expression-Transcription POGIL will be due Tuesday, complete the 6.3 progress check and Start Chapter 17: From Gene to Protein BOOK WORK (Due 2/11)

Chapter 17

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Monday 2/9

1. Transformation Lab 

During Lab: work on Gene Expression-Transcription POGIL (due tomorrow)  

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Tuesday 2/10**

1. Finish Transformation Lab 

• Check Plates

• Discuss and answer analysis

Essential Understanding- 6.4 Translation

2. Translation POGIL (key) print 

3. Eukaryotic Translation (Protein Synthesis), Animation video (3 min)

• Watch on your own so you can rewind and pause. Take THOROUGH notes! 

  • Make sure to include: Initiation, Elongation, Termination, E Site, P Site, A Site 

*6.1, 6.2 and 6.3 Quizzes will be combined

Homework: Chapter 17 Book Work (Due tomorrow)  

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Wednesday 2/11

• Turn in Chapter 17 Book Work 

1) Tazswana Case Study (didn't print last page)

2) Section 6.1, 6.2 and 6.3 Quiz 

• finish Transformation Lab analysis if you have not already (skip question 5)

3) SO COOL: Watch: Central Dogma (3 min) 

4) Eukaryotic and Prokaryotic Differences in Transcription and Translation (3.5 min) 

Homework: Functional Components of Gene Expression- complete on Schoology 

also- Start Chapter 18

Chapter 18: Regulation of Gene Expression BOOK WORK (Due 2/26)

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Thursday 2/12 (Half Day)

1) Discuss/Check Functional Components of Gene Expression

2) Watch: Retroviruses Clip (4 min)- What is so different about them and HOW they behave in respect to DNA and RNA?

3) Take 6.4 Progress Check (FYI: 6.4, 6.5 and 6.6 Section Quizzes will be combined) 

• OPTIONAL (if you did not do well on that progress check, Watch Section 6.4 Daily Video 1 (8 min) and Video 2 (7 min)

Essential Understanding- 6.5 Regulation of Gene Expression

4) Regulatory Sequences

• Bozeman Gene Regulation (video worksheet) (print) (10 min) 

• Contols of Gene Expression in Prokaryotes POGIL (key)

• pHet Simulation Gene Expression (complete digitally) 

HWK: Complete up to the extension questions on pHet Simulation Gene Expression continue working on Chapter 18

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Tuesday 2/17

1. 20 minutes to finish pHet Simulation Gene Expression (whatever isn't finished after 20 minutes complete for homework)

2. Modeling Prokaryotic Operons with Pool Noodles (open digitally) 

• Look at the one that was created years ago and discuss 

• SKIPPING: Create your own digital presentation/simulation of a Gene Regulation Event (assigned groups of 4) 
  • • Good Example from Spring 2021
    • BE ABLE TO: 
    •    - Discuss PROG (Promoter, Regulator, Operon, Gene)
    •    - Connect to Gene Expression
    •    - Tie to Cell Communication

3. Epigenetics

• Gene Control- epigenetic tags come and go to change the shape of the gene - remember this

• Epigenetics- Insights from Identical Twins (Nature vs Nurture) (Pins and Ropes) (5 min) 1

4. Cell Specialization and Differentiation (17 min) 

• The phenotype of a cell or organism is determined by the combination of genes that are expressed and the levels at which they are expressed—

Homework: Watch the Section 6.5 Daily Video 1 (8 min) and Video 2 (6 min) and  take 6.5 Progress Check (Key)

Remember: Chapter 18: Regulation of Gene Expression BOOK WORK  (Due 2/26)

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Wednesday 2/18

6.5 2B- Both prokaryotes and eukaryotes have groups of genes that are coordinately regulated—

• WATCH on your own with headphones- Difference between Prokaryotic and Eukaryotic Gene Expression Video (10 min) 

• Create an Organizer to differentiate between Gene regulation and expression by Prokaryotes and Eukaryotes (teacher sample)

Essential Understanding- 6.6 Gene Expression and Cell Specialization

1.  VIDEO: Bozeman- Development: Timing & Coordination (video worksheet) print (13 min) (key)

2. Human Development (2 min) 

3. Embryology Quick Simulation Activity

4.  VIDEO: Bozeman- Mechanisms of Timing & Control (video worksheet) print (10 minutes) (key)

5. Drosophila Melanogaster Hox Genes Coloring 

• Background Video while you color: Genes Control Body Segmentation (PBS) (13 min)

6. Take the 6.6 Progress Check

Reminder: Chapter 18: Regulation of Gene Expression BOOK WORK  is due Wednesday

HMK: study for  6.4, 6.5, 6.6 quiz tomorrow

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Thursday 2/19

1. STEM CELLS

• Watch: The Nature of Stem Cells (3 min) 

• Watch: Unlocking Stem Cell Potential

• Spend 10 minutes clicking through the tabs on this Website

Essential Understanding- 6.7 Mutations (and Viruses)

2. Genetic Mutation POGIL (key) 

3. WATCH: Video- Bozeman: Mutations - Notes - add notes to this started note sheet (7 min)

4. Take 6.7 Progress Check 

Optional: Watch Section 6.7 Daily Video 1 (9 min), Section 6.7 Daily Video 2 (6 min) , Section 6.7 Daily Video 3 (6 min) 

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Friday 2/20

Turn in: Chapter 18: Regulation of Gene Expression BOOK WORK 

1. Section 6.4, 6.5, 6.6 Quiz

Essential Understanding- 6.8 Biotechnology (*check the exclusion statement) 

2. Create Gels for tomorrow's Lab

3. Fast Gels Student Lab (teacher version)

• Read the Background Information Pages and complete the pre-lab questions

• Practice and Get ready for tomorrow's Lab

• Worksheet

• Forensic Fish Scenario Gel Electrophoresis Lab

• Watch: Bozeman: DNA Fingerprinting (6 min)
• Read: Background on DNA Fingerprinting and PCR (read packet in groups) 

4. PCR, Gel Electrophoresis and Genome Maps

• • Bozeman: Molecular Biology (14 min)

  • Polymerase Chain Reaction (PCR): DNA Amplification (5 min) 

Homework: 

1- Watch Section 6.8 Daily Video (7 min) and Take Progress Check 6.8 (key) 

2-  Chapter 20 BOOK WORK (Due Monday 3/3)

Homework: Start Chapter 20 BOOK WORK  

Chapter 20: DNA Tools and Biotechnology (Due 3/3)

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Monday 2/23

1. Section 6.7  and 6.8 Quiz

2. Take 5 minutes to skim through Chapter 19 (Viruses) 

3.  Bozeman: Viruses- take notes (8 min)

4. Unit 6 Progress Checks

5. Practice Essays

6. Class time to work on Chapter 20 BOOK WORK 

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Tuesday 2/24

1. Fast Gels Student Lab (teacher version)

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Wednesday 2/25

Turn in Chapter 20 BOOK WORK 

Unit 6 Essay Test (key)  

Homework: Genomes and Their Evolution Chapter 21 Book Work (due 3/7)

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Thursday 2/26

Unit 6 Multiple Choice Test (key)

Homework: Genomes and Their Evolution Chapter 21 Book Work (due 3/7)