Wednesday 2/4

Essential Understanding- 6.1 DNA and RNA Structure

DNA and RNA REVIEW

1. Create Plates

2. The Discovery of the Stru2cture of DNA Clip (2 min)

3. Rosalind Franklin: She's Worth Another Look (pdf)

• • • go on a tangent for 5 min and find something interesting about her life that was not discussed in this article

    • Rosalind Franklin vs. Watson & Crick - Science History Rap Battle

4. VIDEO: Topic 6.1: DNA & RNA Structure (video worksheet) print (12 min)

5. Purines and Pyrimidines Bonding and Structural Differences

• Purines (Guanine and Adenine) 2 Ring Structures

• Pyrimidines (Thymine, Uracil and Cytosine) 1 Ring Structure

6. So How is Bacteria Different?

• • Bacterial Genetics Clip (4 min)- video worksheet (print) 

7. Plate E.Coli (if its here, crossing fingers!)

HWK) Complete: Transformation Lab Scenarios (s9-s16) and Start Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due 2/6)

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Thursday 2/5 

1. Transformation Lab bead part

2. Take Progress Check 6.1

• After you finish the progress check, check this out:

  • DNA Interactive (spend a few minutes checking this out) 

Essential Understanding- 6.2 Replication

5) 6.2 Lecture Video (16 min) (Video Notes) (15 min)

6) Topoisomerase Activity- Rope; Clay

• video 1 (2 min) and video 2 (2 min)

• DNA Topology (8 min)- DO NOT TAKE NOTES

HWK: Finish Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due  tomorrow)

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Friday 2/6

Turn in Chapter 16 Book Work

1. Plate E.Coli

2. The End Replication Problem! Solution: Telomerase! Watch this video Telomere Replication (2 min)

• Cell Senescence Video (video worksheet) print (10 min) 

• Aging Discussion

3. Take 6.2 Progress Check 

Essential Understanding- 6.3 Transcription and RNA Processing

4. Topic 6.3: Transcription & RNA Processing (17 min) (Video Notes)

5. Exons, Introns, Poly A Tail, GTP Cap explained concisely (5 min)

6. Gene Expression-Transcription POGIL (key)

7. Take 6.3 Progress Check

• (6.1, 6.2 and 6.3 Quiz Wednesday)

Homework: Gene Expression-Transcription POGIL will be due Tuesday, complete the 6.3 progress check and Start Chapter 17: From Gene to Protein BOOK WORK (Due 2/11)

Chapter 17

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Monday 2/9

1. Transformation Lab 

During Lab: work on Gene Expression-Transcription POGIL (due tomorrow)  

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Tuesday 2/10

1. Turn in Transcription POGIL

2. Transformation Lab 

• Check Plates

Essential Understanding- 6.4 Translation

3. Translation POGIL (key) print 

4. Look at this FRQ (minimum number of nucleotides for a certain length polypeptide)

5. Eukaryotic Translation (Protein Synthesis), Animation video (3 min)

• Watch on your own so you can rewind and pause. Take THOROUGH notes! 

  • Make sure to include: Initiation, Elongation, Termination, E Site, P Site, A Site 

*Take 6.3 Progress Check... 6.1, 6.2 and 6.3 Quizzes will be tomorrow

Homework: Chapter 17 Book Work (Due tomorrow)  

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Wednesday 2/11

• Turn in Chapter 17 Book Work 

1. Transformation Lab 

• Check Plates

2. Tazswana Case Study (didn't print last page)

3. Section 6.1, 6.2 and 6.3 Quiz 

• finish Transformation Lab analysis if you have not already (skip question 5)

4. SO COOL: Watch: Central Dogma (3 min) 

5. Eukaryotic and Prokaryotic Differences in Transcription and Translation (3.5 min) (printout)

Homework: Functional Components of Gene Expression- complete on Schoology 

also- Start Chapter 18

Chapter 18: Regulation of Gene Expression BOOK WORK (Due 2/26)

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Thursday 2/12 (Half Day)

1) Discuss/Check Functional Components of Gene Expression

2) Watch: Retroviruses Clip (4 min)- What is so different about them and HOW they behave in respect to DNA and RNA?

3) Take 6.4 Progress Check (FYI: 6.4, 6.5 and 6.6 Section Quizzes will be combined) 

• If you didn't do well on progress check, watch this: 6.4 Translation - AP Biology (Poser Video)

Essential Understanding- 6.5 Regulation of Gene Expression

4) Regulatory Sequences

• Bozeman Gene Regulation (video worksheet) (print) (10 min) 

• Contols of Gene Expression in Prokaryotes POGIL (key)

Homework: Complete Contols of Gene Expression in Prokaryotes POGIL and continue working on Chapter 18

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Tuesday 2/17

1. pHet Simulation Gene Expression (complete digitally) 

2. Show off: Modeling Prokaryotic Operons with Pool Noodles (open digitally) 

• Look at the one that was created years ago and discuss 

3. Create your own digital presentation/simulation of a Gene Regulation Event (assigned groups of 4) 

• • • Example
    • BE ABLE TO: 
    •    - Discuss PROG (Promoter, Regulator, Operon, Gene)
    •    - Connect to Gene Expression
    •    - Tie to Cell Communication

4. Cell Specialization and Differentiation (17 min) (handout)

• The phenotype of a cell or organism is determined by the combination of genes that are expressed and the levels at which they are expressed

Homework: Take 6.5 Progress Check 

Remember: Chapter 18: Regulation of Gene Expression BOOK WORK  (Due 2/26)

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Wednesday 2/18

1. Finish: Cell Specialization and Differentiation (17 min) (handout) from yesterday (we stopped at 13 min)

2. Epigenetics

• Gene Control- epigenetic tags come and go to change the shape of the gene - remember this

• Epigenetics- Insights from Identical Twins (Nature vs Nurture) (Pins and Ropes) (5 min)

• Skim through this website: Nutrition & the Epigenome

• Your Environment, Your Epigenome worksheet

3. 6.5 2B- Both prokaryotes and eukaryotes have groups of genes that are coordinately regulated—

• WATCH on your own with headphones- Difference between Prokaryotic and Eukaryotic Gene Expression Video (10 min) 

• Create an Organizer to differentiate between Gene regulation and expression by Prokaryotes and Eukaryotes (teacher sample)

Essential Understanding- 6.6 Gene Expression and Cell Specialization

4. VIDEO: Bozeman- Development: Timing & Coordination (video worksheet) print (13 min) (key)

5. Human Development (2 min) 

6. Embryology Quick Simulation Activity (After you select the right animal, click to see the embryo develop for each of the 4 examples)

7. Drosophila Melanogaster Hox Genes Coloring 

• Background Video while you color: Genes Control Body Segmentation (PBS) (13 min)

8. PoseKnows: 6.6 Gene Expression and Cell Specialization video (7 min) (worksheet)

9. Take the 6.6 Progress Check

Reminder: Chapter 18: Regulation of Gene Expression BOOK WORK  is due Friday

HMK: study for  6.4, 6.5, 6.6 quiz tomorrow

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Thursday 2/19

1. PoseKnows: 6.6 Gene Expression and Cell Specialization video (7 min) (worksheet)

2. STEM CELLS

• Watch: The Nature of Stem Cells (3 min) 

• Watch: Unlocking Stem Cell Potential

3. Take the 6.6 Progress Check

Essential Understanding- 6.7 Mutations (and Viruses)

4. Genetic Mutation POGIL (key) 

5. WATCH: Video- Bozeman: Mutations - Notes - add notes to this started note sheet (7 min)

6. Take 6.7 Progress Check 

Optional: Watch Section 6.7 Daily Video 1 (9 min), Section 6.7 Daily Video 2 (6 min) , Section 6.7 Daily Video 3 (6 min) 

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Friday 2/20

Turn in: Chapter 18: Regulation of Gene Expression BOOK WORK 

1. Section 6.4, 6.5, 6.6 Quiz

Essential Understanding- 6.8 Biotechnology (*check the exclusion statement) 

2. Create Gels for tomorrow's Lab

3. Fast Gels Student Lab (teacher version)

• Read the Background Information Pages and complete the pre-lab questions

• Practice and Get ready for tomorrow's Lab

• Worksheet

• Forensic Fish Scenario Gel Electrophoresis Lab

• Watch: Bozeman: DNA Fingerprinting (6 min)
• Read: Background on DNA Fingerprinting and PCR (read packet in groups) 

4. PCR, Gel Electrophoresis and Genome Maps

• • Bozeman: Molecular Biology (14 min)

  • Polymerase Chain Reaction (PCR): DNA Amplification (5 min) 

Homework: Take Progress Check 6.8 

Homework: Start Chapter 20 BOOK WORK  due (3/3)

Chapter 20: DNA Tools and Biotechnology (Due 3/3)

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Monday 2/23

Flexible Instructional Day Musetti Zoom Link

9:00-9:15 Synchronous Homeroom/Check-In/Attendance on Zoom

9:20-9:50 A Block

9:55-10:25 B Block

10:25-10:45 Screen Break

10:45-11:15 C Block

11:20-11:50 D Block

1. Take 2 minutes to skim through Chapter 19 (Viruses) skipping bookwork 

2.  Bozeman: Viruses- take notes (8 min)

3. Practice Essays

• tutorial

4. On your own: Watch Unit 6 Review (42 min) and take Unit 6 Progress Checks

Homework: Chapter 20 BOOK WORK  due Wednesday

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Tuesday 2/24

5. Fast Gels Student Lab (teacher version)

6. During down time: Section 6.7  and 6.8 Quiz

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Wednesday 2/25

Turn in Chapter 20 BOOK WORK (key)

Unit 6 Essay Test (print portion)

Homework: Genomes and Their Evolution Chapter 21 Book Work (due 3/3)

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Thursday 2/26

Unit 6 Multiple Choice Test (key)

Homework: Genomes and Their Evolution Chapter 21 Book Work (due 3/3)

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Friday 2/27

ASSEMBLY/RALLY BLOCK (end of day)

HR: 7:45 – 7:55 (10 minutes)
A: 7:59 – 9:05 (66 minutes)
B: 9:09 – 10:15 (66 minutes)
L & L: 10:15 – 11:15 (60 minutes)
C: 11:19 – 12:25 (66 minutes)
D: 12:29 – 1:35 (66 minutes)
Rally: 1:35 – 2:45 (70 minutes)

1. Finish Fast Gels Student Lab (teacher version) (GEL PICTURE)

Essential Understanding- 7.1 Introduction to Natural Selection

2. ACTIVITY: Beetle Bonanza (printable version of activity) (Teacher Key) ; Alternative Assignment

3. What is Natural Selection? What drives it? (presentation)

4. VIDEO: Bozeman: Natural Selection 10 min (complete worksheet) (print) 

5. DEMO: Peppered Moths

6. ACTIVITY: Natural Selection Scenario Activity (complete digitally) 

Homework: finish all work from today (also Chapter 21 Book Work due 3/3)