Thursday 2/15 (half day)

Create Plates

Plate E.Coli

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Tuesday 2/20

• Skim: Unit 6: Gene Expression and Regulation

Essential Understanding- 6.1 DNA and RNA Structure

DNA and RNA REVIEW

1) The Discovery of the Structure of DNA Clip (2 min)

2) Rosalind Franklin: She's Worth Another Look Reading (pdf)

• • • go on a tangent for 5 min and find something interesting about her life that was not discussed in this article

    • Rosalind Franklin vs. Watson & Crick - Science History Rap Battle

3) VIDEO: Bozeman- DNA & RNA - Part 1  (we already watched this in Unit 4)

4) VIDEO: Bozeman- DNA & RNA - Part 2(video worksheet) print

5) Purines and Pyrimidines Bonding and Structural Differences

• Purines (Guanine and Adenine) 2 Ring Structures

• Pyrimidines (Thymine, Uracil and Cytosine) 1 Ring Structure

5) So How is Bacteria Different?

• • Bacterial Genetics Clip (4 min)- video worksheet (print) 

6) Complete: Transformation Lab Scenarios (s9-s16) 

HWK) Start Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due 2/22)

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Wednesday 2/21

1) Swap Scenarios with your neighbor- discuss

2)  Transformation Lab bead part

3) Transformation Lab 

*6.1, 6.2 and 6.3 Quizzes will be combined (next Friday 3/3) 

HWK: Finish Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due  tomorrow)

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Thursday 2/22

Turn in Chapter 16 Book Work

Check Plates

1) Watch AP Central's 6.1 Daily Video (8 min) as a class and pause to do the questions together

•  Take Progress Check 6.1 (Key)

• After you finish the progress check, check this out:

  • DNA Interactive (spend a few minutes checking this out) 

Essential Understanding- 6.2 Replication

2) DNA Replication worksheet (print) 

• do as much as you can and then fill in the rest while watching the following video

3) 6.2 Lecture Video (16 min) Take Notes

4) Topoisomerase Activity- Rope; Clay

• video 1 and video 2

• DNA Topology

5) The End Replication Problem! Solution: Telomerase! Watch this video Telomere Replication

• Cell Senescence Video (video worksheet) print

• Aging Discussion

6) Take 6.2 Progress Check (key) 

Homework: Start Chapter 17: From Gene to Protein BOOK WORK (Due 2/28)

Chapter 17

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Friday 2/23

Essential Understanding- 6.3 Transcription and RNA Processing

Homework Check- Telomers

1) 6.3 Transcription and RNA Processing - AP Biology  (14 min) Take Notes

2) Exons, Introns, Poly A Tail, GTP Cap explained concisely

3) Gene Expression-Transcription POGIL (key)

4)  Tazswana Case Study (Key) complete verbally by reading digitally as a class

Homework: Finish Gene Expression-Transcription POGIL

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Monday 2/26

• Check Plates

1) Finish Tazswana Case Study

Take 6.3 Progress Check

• (6.1, 6.2 and 6.3 Quiz tomorrow) 

• Optional Homework: Watch 6.3 Daily Video 1 and  Video 2  and 

2) Watch: Crash Course: DNA and Protein Synthesis (14 min)

Essential Understanding- 6.4 Translation

3) Translation POGIL (key) print 

pushed to tomorrow:  Eukaryotic Translation (Protein Synthesis), Animation video (3 min)

• Watch on your own so you can rewind and pause. Take THOROUGH notes! 

  • Make sure to include: Initiation, Elongation, Termination, E Site, P Site, A Site 

Homework: Work on: Chapter 17: From Gene to Protein BOOK WORK (Due 2/28)

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Tuesday 2/27

1) Section 6.1, 6.2 and 6.3 Quiz 

• finish Transformation Lab analysis if you have not already (skip question 5)

• Watch: Eukaryotic Translation (Protein Synthesis), Animation video (3 min)

• • Watch on your own so you can rewind and pause. Take THOROUGH notes! 
  • Make sure to include: Initiation, Elongation, Termination, E Site, P Site, A Site 

2) SO COOL: Watch: Central Dogma (3 min) 

3) Eukaryotic and Prokaryotic Differences in Transcription and Translation

4) Functional Components of Gene Expression- complete together in groups of 3/4 (not printing) 

5) Retroviruses Clip (4 min)- What is so different about them and HOW they behave in respect to DNA and RNA?

6) Remaining Class time, work on Chapter 17: From Gene to Protein BOOK WORK

HWK:  Chapter 17 Book Work (Due tomorrow)  and Take 6.4 Progress Check (FYI: 6.4, 6.5 and 6.6 Section Quizzes will be combined) 

OPTIONAL: Watch Section 6.4 Daily Video 1 (8 min) and Video 2 (7 min)

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Wednesday 2/28

• Turn in Chapter 17 Book Work 

Essential Understanding- 6.5 Regulation of Gene Expression

Describe the types of interactions that regulate gene expression

1) Regulatory Sequences

• Bozeman Gene Regulation (video worksheet) (print) (10 min) 

• Contols of Gene Expression in Prokaryotes POGIL (key)** 

• pHet Simulation Gene Expression (complete digitally) 

2) Epigenetics

• Gene Control- epigenetic tags come and go to change the shape of the gene - remember this

• Epigenetics- Insights from Identical Twins (Nature vs Nurture) (Pins and Ropes) (5 min) 

HWK: Start Chapter 18

Chapter 18: Regulation of Gene Expression BOOK WORK (Due 3/6)

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Thursday 2/29 (LEAP YEAR!)

1) Modeling Prokaryotic Operons with Pool Noodles (open digitally) 

• Look at last years and improve/fix

2) Control Mechanism -lac and trp operons worksheet (teacher copy) print

3) Create your own digital presentation/simulation of a Gene Regulation Event (assigned groups of 4) 

• • • Good Example from Spring 2021

    • BE ABLE TO: 

    •    - Discuss PROG (Promoter, Regulator, Operon, Gene)

    •    - Connect to Gene Expression

    •    - Tie to Cell Communication

Remember: Chapter 18: Regulation of Gene Expression BOOK WORK  (Due 3/6)

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Friday 3/1

1) Look at another groups digital PROG presentation from yesterday

• • •    - Discuss PROG (Promoter, Regulator, Operon, Gene)

    •    - Connect to Gene Expression

    •    - Tie to Cell Communication

2) The phenotype of a cell or organism is determined by the combination of genes that are expressed and the levels at which they are expressed—

• Cell Specialization and Differentiation (17 min) 

3) March Madness 

Homework: Watch the Section 6.5 Daily Video 1 (8 min) and Video 2 (6 min) and  then Take 6.5 Progress Check (Key)

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Monday 3/4

1) 6.5 2B- Both prokaryotes and eukaryotes have groups of genes that are coordinately regulated—

• WATCH - Difference between Prokaryotic and Eukaryotic Gene Expression Video (10 min) and  Create an Organizer to differentiate between Gene regulation and expression by Prokaryotes and Eukaryotes (teacher sample)

Essential Understanding- 6.6 Gene Expression and Cell Specialization

2) VIDEO: Bozeman- Development: Timing & Coordination (video worksheet) print (13 min) 

3)  Human Development (2 min) 

4) Embryology Quick Simulation Activity

5) Watch the Section 6.6 Daily Video (6 min)  and then take the  Progress Check 6.6 (key)  and study for  6.4, 6.5, 6.6 quiz tomorrow

6) if there is time at the end, start homework (remember Chapter 18: Regulation of Gene Expression BOOK WORK  is due Wednesday) 

HMK: study for  6.4, 6.5, 6.6 quiz tomorrow

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Tuesday 3/5

1) VIDEO: Bozeman- Mechanisms of Timing & Control (video worksheet) print (10 minutes) 

2) VIDEO: Genes Control Body Segmentation (PBS) (13 min)

• FOR NEXT YEAR: Drosophila Melanogaster Hox Genes Coloring 

3) Section 6.4, 6.5, 6.6 Quiz

After Quiz- 

• Read and Annotate- The genetic basis of adaptive melanism in pocket mice

Homework: Finish Annotating The genetic basis of adaptive melanism in pocket mice

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Wednesday 3/6

• Turn in: Chapter 18: Regulation of Gene Expression BOOK WORK 

1) STEM CELLS

• Watch: The Nature of Stem Cells (3 min) 

• Watch: Unlocking Stem Cell Potential

• Spend 10 minutes clicking through the tabs on this Website

Essential Understanding- 6.7 Mutations (and Viruses)

2) Genetic Mutation POGIL (key) 

3) WATCH: Video- Bozeman: Mutations - Notes - add notes to this started note sheet (7 min)

4) Pocket Mice!

• Play with the scroll on this simulation- Pocket Mice

• discuss annotated paper: The genetic basis of adaptive melanism in pocket mice

• Watch portion of Natural Selection and the Rock Pocket Mouse (7min- 9:30) 

5) Optional: Watch Section 6.7 Daily Video 1 (9 min), Section 6.7 Daily Video 2 (6 min) , Section 6.7 Daily Video 3 (6 min) 

6) Take 6.7 Progress Check 

Homework: Start Chapter 20 BOOK WORK  and Take Progress Check 6.7

Chapter 20: DNA Tools and Biotechnology (Due 3/11)

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Thursday 3/7

Essential Understanding- 6.8 Biotechnology (*check the exclusion statement) 

1) Gel Electrophoresis Simulation website

• Worksheet

• Forensic Fish Scenario Gel Electrophoresis Lab

• Watch: Bozeman: DNA Fingerprinting (6 min)
• Read: Background on DNA Fingerprinting and PCR (read packet in groups) 

2) PCR

• • PCR (11 min) 

  • Bozeman: Molecular Biology (14 min)

3) READ: Restriction Enzyme Hand Out (look over digitally) (Legacy Project; retype) 

Homework: 

1- Watch Section 6.8 Daily Video (7 min) and Take Progress Check 6.8 (key) 

2-  Chapter 20 BOOK WORK (Due 3/11)

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Friday 3/8

1) Section 6.7  and 6.8 Quiz

2) Take 5 minutes to skim through Chapter 19 (Viruses) 

3) Bozeman: Viruses- take notes (8 min)

4) Unit 6 Progress Checks

5) Practice Essays

6) Class time to work on Chapter 20 BOOK WORK 

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Monday 3/11

• Turn in Chapter 20 BOOK WORK 

Unit 6 Essay Test (key)  

Homework: Genomes and Their Evolution Chapter 21 Book Work (due 3/15)

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Tuesday 3/12

Unit 6 Multiple Choice Test (key)

Homework: Genomes and Their Evolution Chapter 21 Book Work (due 3/15)