2024/2025 AP BIOLOGY - Unit 6: Gene Expression and Regulation

Unit 6: Gene Expression and Regulation

Friday 2/7

Essential Understanding- 6.1 DNA and RNA Structure

DNA and RNA REVIEW

1) Create Plates

2) The Discovery of the Structure of DNA Clip (2 min)

3) Rosalind Franklin: She's Worth Another Look (pdf)

- - go on a tangent for 5 min and find something interesting about her life that was not discussed in this article
  - Rosalind Franklin vs. Watson & Crick - Science History Rap Battle

4) VIDEO: Bozeman- DNA & RNA - Part 1 (we already watched this in Unit 4) (13 min)

5) VIDEO: Bozeman- DNA & RNA - Part 2(video worksheet) print (10 min)

6) Purines and Pyrimidines Bonding and Structural Differences

Purines (Guanine and Adenine) 2 Ring Structures
Pyrimidines (Thymine, Uracil and Cytosine) 1 Ring Structure

7) So How is Bacteria Different?

- Bacterial Genetics Clip (4 min)- video worksheet (print)

8) Plate E.Coli

HWK) Complete: Transformation Lab Scenarios (s9-s16) and Start Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due 2/11)

Optional Resources:Book Power PointClicker Power PointBook Power PointClicker QuestionsPower pointLecture I and IIChapter 16 Reading GuideChapter 16 Practice Test. CHECK THIS OUT!!

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Monday 2/10

1) Transformation Lab

During Lab: Swap Scenarios with your neighbor- discuss

*6.1, 6.2 and 6.3 Quizzes will be combined

HWK: Finish Chapter 16: The Molecular Basis of Inheritance BOOK WORK (Due tomorrow)

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Tuesday 2/11

Turn in Chapter 16 Book Work

Check Plates

1) Transformation Lab bead part

2) Watch AP Central's 6.1 Daily Video (8 min) as a class and pause to do the questions together

Take Progress Check 6.1 (Key)
After you finish the progress check, check this out:
- DNA Interactive (spend a few minutes checking this out)

Essential Understanding- 6.2 Replication

CHECK EXCLUSION STATEMENT

4) DNA Replication worksheet (print)

do as much as you can and then fill in the rest while watching the following video

5) 6.2 Lecture Video (16 min) Take Notes

6) Topoisomerase Activity- Rope; Clay

video 1 (2 min) and video 2 (2 min)
DNA Topology (8 min)

7) The End Replication Problem! Solution: Telomerase! Watch this video Telomere Replication (2 min)

Cell Senescence Video (video worksheet) print (10 min)
Aging Discussion

8) Take 6.2 Progress Check (key)

Homework: Start Chapter 17: From Gene to Protein BOOK WORK (Due 2/19)

Chapter 17

Optional ResourcesTranslation (mRNA to Protein) Stages of Translation Book Power PointClicker QuestionsPower pointLecture I and II and IIIChapter 17 Reading Guide REVIEW: DNA Replication and RNA Transcription and Translation

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Wednesday 2/12

1) Finish Transformation Lab

Check Plates

Discuss and answer analysis

Essential Understanding- 6.3 Transcription and RNA Processing

2) 6.3 Transcription and RNA Processing - AP Biology (14 min) Take Notes

3) Exons, Introns, Poly A Tail, GTP Cap explained concisely (5 min)

SKIPPING: DNA Transciption Processing Video (11 min) (Video Handout) print

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Thursday 2/13 (half day)

1) Gene Expression-Transcription POGIL (key)

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Friday 2/14 HAPPY VALENTINE'S DAY

Monday 2/17- President's Day

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Tuesday 2/18- Substitute

Take 6.3 Progress Check

(6.1, 6.2 and 6.3 Quiz tomorrow)

Watch 6.3 Daily Video 1 and Video 2 (Watch them on CollegeBoard. It tells me if you've watched them)

Watch: Crash Course: DNA and Protein Synthesis (14 min)

Essential Understanding- 6.4 Translation

Translation POGIL (key) print
Eukaryotic Translation (Protein Synthesis), Animation video (3 min)

Watch on your own so you can rewind and pause. Take THOROUGH notes!
- Make sure to include: Initiation, Elongation, Termination, E Site, P Site, A Site

Homework: Chapter 17 Book Work (Due tomorrow)

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Wednesday 2/19

Turn in Chapter 17 Book Work

1) Tazswana Case Study

2) Section 6.1, 6.2 and 6.3 Quiz

finish Transformation Lab analysis if you have not already (skip question 5)

3) SO COOL: Watch: Central Dogma (3 min)

4) Eukaryotic and Prokaryotic Differences in Transcription and Translation (3.5 min)

Homework: Functional Components of Gene Expression- complete on Schoology

also- Start Chapter 18

Chapter 18: Regulation of Gene Expression BOOK WORK (Due 2/26)

Optional Resources:Book Power PointClicker QuestionsLecture

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Thursday 2/20

1) Discuss/Check Functional Components of Gene Expression

2) Watch: Retroviruses Clip (4 min)- What is so different about them and HOW they behave in respect to DNA and RNA?

3) Take 6.4 Progress Check (FYI: 6.4, 6.5 and 6.6 Section Quizzes will be combined)

OPTIONAL (if you did not do well on that progress check, Watch Section 6.4 Daily Video 1 (8 min) and Video 2 (7 min)

Essential Understanding- 6.5 Regulation of Gene Expression

4) Regulatory Sequences

Bozeman Gene Regulation (video worksheet) (print) (10 min)
Contols of Gene Expression in Prokaryotes POGIL (key)
pHet Simulation Gene Expression (complete digitally)

HWK: Complete up to the extension questions on pHet Simulation Gene Expression continue working on Chapter 18

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Friday 2/21

20 minutes to finish pHet Simulation Gene Expression (whatever isn't finished after 20 minutes complete for homework)
Modeling Prokaryotic Operons with Pool Noodles (open digitally)

Look at the one that was created years ago and discuss
SKIPPING: Create your own digital presentation/simulation of a Gene Regulation Event (assigned groups of 4)
- - Good Example from Spring 2021
  - BE ABLE TO:
  - - Discuss PROG (Promoter, Regulator, Operon, Gene)
  - - Connect to Gene Expression
  - - Tie to Cell Communication

Epigenetics

Gene Control- epigenetic tags come and go to change the shape of the gene - remember this
Epigenetics- Insights from Identical Twins (Nature vs Nurture) (Pins and Ropes) (5 min) 1

Cell Specialization and Differentiation (17 min)

The phenotype of a cell or organism is determined by the combination of genes that are expressed and the levels at which they are expressed—

Homework: Watch the Section 6.5 Daily Video 1 (8 min) and Video 2 (6 min) and take 6.5 Progress Check (Key)

Remember: Chapter 18: Regulation of Gene Expression BOOK WORK (Due 2/26)

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Monday 2/24

6.5 2B- Both prokaryotes and eukaryotes have groups of genes that are coordinately regulated—

WATCH on your own with headphones- Difference between Prokaryotic and Eukaryotic Gene Expression Video (10 min)
Create an Organizer to differentiate between Gene regulation and expression by Prokaryotes and Eukaryotes (teacher sample)

Essential Understanding- 6.6 Gene Expression and Cell Specialization

VIDEO: Bozeman- Development: Timing & Coordination (video worksheet) print (13 min) (key)
Human Development (2 min)

Skipping) QUICK SCAN OF THIS VIDEO: Early embryogenesis- Cleavage, Blastulation, Gastrulation, and Neurulation- you DO NOT need to know it on this scale (12 min)