Publications

22. Roh SH, Mendez-Vazquez H, Sathler MF, Doolittle MJ, Zaytseva A, Brown H, Sainsbury M, Kim S. Prenatal exposure to valproic acid reduces synaptic δ-catenin levels and disrupts ultrasonic vocalization in neonates. Neuropharmacology. 2024 Aug 1;253:109963. doi: 10.1016/j.neuropharm.2024.109963. Epub 2024 Apr 23. PubMed PMID: 38657945; PubMed Central PMCID: PMC11127754.

21. Zaytseva A, Bouckova E, Wiles MJ, Wustrau MH, Schmidt IG, Mendez-Vazquez H, Khatri L, Kim S. Ketamine's rapid antidepressant effects are mediated by Ca(2+)-permeable AMPA receptors. Elife. 2023 Jun 26;12. doi: 10.7554/eLife.86022. PubMed PMID: 37358072; PubMed Central PMCID: PMC10319435.

20. Mendez-Vazquez H, Roach RL, Nip K, Chanda S, Sathler MF, Garver T, Danzman RA, Moseley MC, Roberts JP, Koch ON, Steger AA, Lee R, Arikkath J, Kim S.The autism-associated loss of δ-catenin functions disrupts social behavior. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2300773120. doi: 10.1073/pnas.2300773120. Epub 2023 May 22. PubMed PMID: 37216537.

19. Sathler MF, Doolittle MJ, Cockrell JA, Nadalin IR, Hofmann F, VandeWoude S, Kim S. HIV and FIV glycoproteins increase cellular tau pathology via cGMP-dependent kinase II activation. J Cell Sci. 2022 Jun 15;135(12). doi: 10.1242/jcs.259764. Epub 2022 Jun 21. PubMed PMID: 35638570; PubMed Central PMCID: PMC9270957.

18. Pensalfini A, Jiang Y, Kim S, Nixon RA. Assessing Rab5 Activation in Health and Disease. Methods Mol Biol. 2021;2293:273-294. doi: 10.1007/978-1-0716-1346-7_20. PubMed PMID: 34453725.

17. Sathler MF, Khatri L, Roberts JP, Schmidt IG, Zaytseva A, Kubrusly RCC, Ziff EB, Kim S. Phosphorylation of the AMPA receptor subunit GluA1 regulates clathrin-mediated receptor internalization. J Cell Sci. 2021 Sep 1;134(17). doi: 10.1242/jcs.257972. Epub 2021 Sep 7. PubMed PMID: 34369573; PubMed Central PMCID: PMC8445600.

16. Tran TM, Sherwood JK, Doolittle MJ, Sathler MF, Hofmann F, Stone-Roy LM, Kim S. Loss of cGMP-dependent protein kinase II alters ultrasonic vocalizations in mice, a model for speech impairment in human microdeletion 4q21 syndrome. Neurosci Lett. 2021 Aug 10;759:136048. doi: 10.1016/j.neulet.2021.136048. Epub 2021 Jun 12. PubMed PMID: 34126178; NIHMSID:NIHMS1714892.

15. Roberts JP, Stokoe SA, Sathler MF, Nichols RA, Kim S. Selective coactivation of α7- and α4β2-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction. J Biol Chem. 2021 Jan-Jun;296:100402. doi: 10.1016/j.jbc.2021.100402. Epub 2021 Feb 9. PubMed PMID: 33571523; PubMed Central PMCID: PMC7961090.

14. Pensalfini A, Kim S, Subbanna S, Bleiwas C, Goulbourne CN, Stavrides PH, Jiang Y, Lee JH, Darji S, Pawlik M, Huo C, Peddy J, Berg MJ, Smiley JF, Basavarajappa BS, Nixon RA. Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease. Cell Rep. 2020 Nov 24;33(8):108420. doi: 10.1016/j.celrep.2020.108420. PubMed PMID: 33238112; PubMed Central PMCID: PMC7714675. 

13. Sun JL, Stokoe SA, Roberts JP, Sathler MF, Nip KA, Shou J, Ko K, Tsunoda S, Kim S. Co-activation of selective nicotinic acetylcholine receptors is required to reverse beta amyloid-induced Ca2+ hyperexcitation. Neurobiol Aging. 2019 Dec;84:166-177. doi: 10.1016/j.neurobiolaging.2019.09.005. Epub 2019 Sep 19. PubMed PMID: 31629115; PubMed Central PMCID: PMC6960326. 

12. Shou J, Tran A, Snyder N, Bleem E, Kim S. Distinct Roles of GluA2-lacking AMPA Receptor Expression in Dopamine D1 or D2 Receptor Neurons in Animal Behavior. Neuroscience. 2019 Feb 1;398:102-112. doi: 10.1016/j.neuroscience.2018.12.002. Epub 2018 Dec 8. PubMed PMID: 30537522. 

11. Sztukowski K, Nip K, Ostwald PN, Sathler MF, Sun JL, Shou J, Jorgensen ET, Brown TE, Elder JH, Miller C, Hofmann F, VandeWoude S, Kim S. HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model. PLoS Biol. 2018 Jul;16(7):e2005315. doi: 10.1371/journal.pbio.2005315. eCollection 2018 Jul. PubMed PMID: 30052626; PubMed Central PMCID: PMC6082575. 

10. Kim S, Shou J, Abera S, Ziff EB. Sucrose withdrawal induces depression and anxiety-like behavior by Kir2.1 upregulation in the nucleus accumbens. Neuropharmacology. 2018 Mar 1;130:10-17. doi: 10.1016/j.neuropharm.2017.11.041. Epub 2017 Nov 27. PubMed PMID: 29191750. 

9. Farooq M, Kim S, Patel S, Khatri L, Hikima T, Rice ME, Ziff EB. Lithium increases synaptic GluA2 in hippocampal neurons by elevating the δ-catenin protein. Neuropharmacology. 2017 Feb;113(Pt A):426-433. doi: 10.1016/j.neuropharm.2016.10.025. Epub 2016 Oct 25. PubMed PMID: 27793771; PubMed Central PMCID: PMC5434258. 

8. Park JY, Dus M, Kim S, Abu F, Kanai MI, Rudy B, Suh GSB. Drosophila SLC5A11 Mediates Hunger by Regulating K(+) Channel Activity. Curr Biol. 2016 Aug 8;26(15):1965-1974. doi: 10.1016/j.cub.2016.05.076. Epub 2016 Jul 7. PubMed PMID: 27397890; PubMed Central PMCID: PMC4980193. 

7. Kim S, Pick JE, Abera S, Khatri L, Ferreira DD, Sathler MF, Morison SL, Hofmann F, Ziff EB. Brain region-specific effects of cGMP-dependent kinase II knockout on AMPA receptor trafficking and animal behavior. Learn Mem. 2016 Aug;23(8):435-41. doi: 10.1101/lm.042960.116. Print 2016 Aug. PubMed PMID: 27421896; PubMed Central PMCID: PMC4947234. 

6. Kim S, Sato Y, Mohan PS, Peterhoff C, Pensalfini A, Rigoglioso A, Jiang Y, Nixon RA. Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease. Mol Psychiatry. 2016 May;21(5):707-16. doi: 10.1038/mp.2015.97. Epub 2015 Jul 21. PubMed PMID: 26194181; PubMed Central PMCID: PMC4721948. 

5. Kim S, Violette CJ, Ziff EB. Reduction of increased calcineurin activity rescues impaired homeostatic synaptic plasticity in presenilin 1 M146V mutant. Neurobiol Aging. 2015 Dec;36(12):3239-3246. doi: 10.1016/j.neurobiolaging.2015.09.007. Epub 2015 Sep 18. PubMed PMID: 26455952; PubMed Central PMCID: PMC4641803. 

4. Kim S, Titcombe RF, Zhang H, Khatri L, Girma HK, Hofmann F, Arancio O, Ziff EB. Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca2+-permeable AMPA receptors. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3122-7. doi: 10.1073/pnas.1417498112. Epub 2015 Feb 23. PubMed PMID: 25713349; PubMed Central PMCID: PMC4364185. 

3. Kim S, Ziff EB. Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors. PLoS Biol. 2014 Jul;12(7):e1001900. doi: 10.1371/journal.pbio.1001900. eCollection 2014 Jul. PubMed PMID: 24983627; PubMed Central PMCID: PMC4077568. 

2. Wincott CM, Kim S, Titcombe RF, Tukey DS, Girma HK, Pick JE, Devito LM, Hofmann F, Hoeffer C, Ziff EB. Spatial memory deficits and motor coordination facilitation in cGMP-dependent protein kinase type II-deficient mice. Neurobiol Learn Mem. 2013 Jan;99:32-7. doi: 10.1016/j.nlm.2012.10.003. Epub 2012 Oct 24. PubMed PMID: 23103773; PubMed Central PMCID: PMC3541678. 

1. Kim S, Lapham AN, Freedman CG, Reed TL, Schmidt WK. Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme. J Biol Chem. 2005 Jul 29;280(30):27481-90. doi: 10.1074/jbc.M414192200. Epub 2005 Jun 8. PubMed PMID: 15944156.