森川雅行

略歴

2022年4月 徳島文理大学, 薬学部, 助教 

2016年4月 徳島文理大学, 香川薬学部, 助教 

専門分野

生物物理化学　構造生物化学

所属学会

日本薬学会 

日本化学会 

日本光医学・光生物学会 

日本環境変異原学会

日本分子生物学会 

担当授業

物理・化学実習

薬学専門研究

薬学演習

基礎有機化学1

 有機化学演習

研究内容

損傷塩基修復酵素hOGG1による塩基除去反応の触媒機構解析

業績

詳細はResearchmap(外部サイト)をご覧ください

1. Masaki Unno*,†, Masayuki Morikawa†, Vladimír Sychrovský, Masataka Koga, Nozomi Minowa, Saki Komuro, Mami Shimizu, Mariko Fukuta, Fuuka Tsuyuguchi, Haruka Mano, Yusuke Ochi, Katsuyuki Nakashima, Yasuko Okamoto, Tomohide Saio, Yoshikazu Hattori*, Yoshiyuki Tanaka* Capturing a glycosylase reaction intermediate in DNA repair by freeze-trapping of a pH-responsive hOGG1 mutant. Nucleic Acids Research, 53, (2025) in press. (DOI: 10.1093/nar/gkaf718)

2. N′1,N′4-bis(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene)succinohydrazide, Taishu Kawada, Katsuhito Kino, Yoshihiko Matsuzawa, Masayuki Morikawa, Yasuko Okamoto, Takanobu Kobayashi, Yoshiyuki Tanaka, Molbank 2022(3) M1436-M1436 2022年8月30日

3. Physicochemical Characterization of the Catalytic Unit of Hammerhead Ribozyme and Its Relationship with the Catalytic Activity, Yoshiyuki Tanaka, Daichi Yamanaka, Saori Morioka, Taishi Yamaguchi, Masayuki Morikawa, Takashi S. Kodama, Vladimír Sychrovský, Chojiro Kojima, Yoshikazu Hattori, Biophysica 2(3) 221-239 2022年8月25日

4. Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by DNA polymerases., Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima, Hiroshi Miyazawa, Genes Environ. 44(1) 7-7 2022年2月15日

5. Considering Existing Factors That May Cause Radiation Hormesis at <100 mSv and Obey the Linear No-Threshold Theory at ≥100 mSv., Katsuhito Kino, Takayuki Ohshima, Hajime Takeuchi, Takanobu Kobayashi, Taishu Kawada, Masayuki Morikawa, Hiroshi Miyazawa, Challenges 12(2) 33-33 2021年12月4日

6. Products of Oxidative Guanine Damage Form Base Pairs with Guanine., Katsuhito Kino, Taishu Kawada, Masayo Hirao-Suzuki, Masayuki Morikawa, Hiroshi Miyazawa, Int. J. Mol. Sci. 21(20) 7645 2020年10月15日

7. Design and concise synthesis of novel vitamin D analogues bearing a functionalized aromatic ring on the side chain., Toshie Fujishima, Takuro Komatsu, Yuri Takao, Wataru Yonamine, Tsutomu Suenaga, Hiroaki Isono, Masayuki Morikawa, Keisuke Takaguchi, Tetrahedron 75(8) 1098-1106 2019年2月

8. Generation, repair and replication of guanine oxidation products., Kino K, Hirao-Suzuki M, Morikawa M, Sakaga A, Miyazawa H., Genes Environ. 39(21) 1-8 2017年8月

9. Contiguous 2,2,4-triamino-5(2H)-oxazolone obstructs DNA synthesis by DNA polymerases α, β, η, ι, κ, REV1 and Klenow Fragment exo-, but not by DNA polymerase ζ., Suzuki M, Kino K, Kawada T, Oyoshi T, Morikawa M, Kobayashi T, Miyazawa H, J. Biochem. 159(3) 323-329 2016年3月

10. グアニンの1電子酸化反応, 喜納 克仁, 鈴木 雅代, 森川 雅行, 放射線生物研究 50(4) 305-320 2015年12月

11. G-Quadruplex DNA- and RNA-Specific-Binding Proteins Engineered from the RGG Domain of TLS/FUS., Kentaro Takahama, Arisa Miyawaki, Takumi Shitara, Keita Mitsuya, Masayuki Morikawa, Masaki Hagihara, Katsuhito Kino, Ayumu Yamamoto, Takanori Oyoshi, ACS Chem. Biol. 10(11) 2564-2569 2015年11月

12. Calculation of the HOMO localization of Tetrahymena and Oxytricha telomeric quadruplex DNA., Masayuki Morikawa, Katsuhito Kino, Takanori Oyoshi, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, Bioorg. Med. Chem. Lett. 25(16) 3359-3362 2015年8月

13. Analysis of Nucleotide Insertion Opposite 2,2,4-Triamino-5(2H)-oxazolone by Eukaryotic B- and Y-Family DNA Polymerases., Masayo Suzuki, Katsuhito Kino, Taishu Kawada, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, Chem. Res. Toxicol. 28(6) 1307-1316 2015年6月

14. Transcriptional Regulation of Tal2 Gene by All-trans Retinoic Acid (atRA) in P19 Cells., Takanobu Kobayashi, Masayo Suzuki, Masayuki Morikawa, Katsuhito Kino, Sei-ichi Tanuma, Hiroshi Miyazawa, Biol. Pharm. Bull. 38(2) 248-256 2015年2月

15. Chlorella virus pyrimidine dimer glycosylase and Escherichia coli endonucleases IV and v have incision activity on 2,2,4-triamino- 5(2H)-oxazolone., Katsuhito Kino, Masayo Suzuki, Masayuki Morikawa, Takanobu Kobayashi, Shigenori Iwai, Hiroshi Miyazawa, Genes and Environment 37(1) 1-6 2015年

16. Effects of stability of base pairs containing an oxazolone on DNA elongation., Masayo Suzuki, Kazuya Ohtsuki, Katsuhito Kino, Teruhiko Kobayashi, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, Journal of Nucleic Acids 2014(178350) 1-9 2014年12月7日

17. N'-[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide., Masayuki Morikawa, Katsuhito Kino, Eriko Asada, Kosuke Katagiri, Kanami Mori-Yasumoto, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, MolBank 2014(4) 1-5 2014年10月28日

18. Calculating Distortions of Short DNA Duplexes with Base Pairing Between an Oxidatively Damaged Guanine and a Guanine, Masayo Suzuki, Katsuhito Kino, Masayuki Morikawa, Takanobu Kobayashi, Hiroshi Miyazawa, MOLECULES 19(8) 11030-11044 2014年8月

19. Formation of a Flavin-Linked Peptide, Masayuki Morikawa, Katsuhito Kino, Takeshi Senda, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, MOLECULES 19(7) 9552-9561 2014年7月

20. Analysis of guanine oxidation products in double-stranded DNA and proposed guanine oxidation pathways in single-stranded, double-stranded or quadruplex DNA, Masayuki Morikawa, Katsuhito Kino, Takanori Oyoshi, Masayo Suzuki, Takanobu Kobayashi, Hiroshi Miyazawa, Biomolecules 4(1) 140-159 2014年3月1日

21. Product analysis of photooxidation in isolated quadruplex DNA; 8-oxo-7,8-dihydroguanine and its oxidation product at 3’-G are formed instead of 2,5- diamino-4H-imidazol-4-one, Masayuki Morikawa, Katsuhito Kino, Takanori Oyoshi, Masayo Suzuki, Takanobu Kobayashia, Hiroshi Miyazawa, RSC Advances 3(48) 25694-25697 2013年

22. Calculation of the Stabilization Energies of Oxidatively Damaged Guanine Base Pairs with Guanine, Masayo Suzuki, Katsuhito Kino, Masayuki Morikawa, Takanobu Kobayashi, Rie Komori, Hiroshi Miyazawa, MOLECULES 17(6) 6705-6715 2012年6月

23. Oxidation of 8-oxoguanine with iodine and proposed mechanisms, Masayuki Morikawa, Katsuhito Kino, Masayo Suzuki, Takanobu Kobayashi, Rie Komori, Hiroshi Miyazawa, Iodine: Characteristics, Sources and Health Implications  121-134 2012年

24. DNA損傷の発生と細胞への影響に関する化学的視点, 森川 雅行, 喜納 克仁, 宮澤 宏, 放射線生物研究 45(3) 268-285 2010年9月

25. The oxidation of 8-oxo-7,8-dihydroguanine by iodine., Katsuhito Kino, Masayuki Morikawa, Teruhiko Kobayashi, Takanobu Kobayashi, Rie Komori, Yoshihisa Sei, Hiroshi Miyazawa, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(12) 3818-3820 2010年6月

26. The oxidation of 2'-deoxy-8-oxoguanosine by iodine., Morikawa M, Kobayashi T, Kobayashi T, Komori R, Sei Y, Miyazawa H, Kino K, Nucleic acids symposium series (2004) (53) 219-220 2009年