PUBLICATIONS

2025

Avogo EW#, Burlingame NA#, Badenahalli Narasimhaiah S#, Delorme-Axford E* (#OU student; *corresponding author). 2025. Bioinformatics analysis identifies Mot2 protein as a potential regulator of autophagy in Saccharomyces cerevisiae. microPublication Biology. doi: 10.17912/micropub.biology.001698

2023

Delorme-Axford E*, Tasmi TA#, Klionsky DJ  (*corresponding author; #OU student). The Pho23-Rpd3 histone deacetylase complex regulates the yeast metabolic transcription factor Stb5. microPublication Biology. 2023. doi: 10.17912/micropub.biology.00094

Delorme-Axford E*, Wen X, and Klionsky DJ* (*co-corresponding author). The yeast transcription factor Stb5 acts as a negative regulator of autophagy by modulating cellular metabolism. Autophagy. 2023 Oct;19(10):2719-2732. Epub 2023 Jul 2. doi: 10.1080/15548627.2023.2228533  

2022

González-Rodríguez P, Delorme-Axford E, Bernard A, Keane L, Stratoulias V, Grabert K, Engskog-Vlachos P, Füllgrabe J, Klionsky DJ, Joseph B. SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome-lysosome fusion. Cell Death Dis. 2022 Nov 12;13(11):953. doi: 10.1038/s41419-022-05381-9.

Lahiri V, Metur SP, Hu Z, Song X, Mari M, Hawkins WD, Bhattarai J, Delorme-Axford E, Reggiori F, Tang D, Dengjel J, Klionsky DJ. Post-transcriptional regulation of ATG1 is a critical node that modulates autophagy during distinct nutrient stresses. Autophagy. 2022 Jul;18(7):1694-1714. doi: 10.1080/15548627.2021.1997305. 

2021

Klionsky DJ et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th ed.). Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. 

2020

Delorme-Axford E and Klionsky DJ. Highlights in the fight against COVID-19: Does autophagy play a role in SARS-CoV-2 infection? Autophagy. 2020 Dec;16(12):2123-27. doi: 10.1080/15548627.2020.1844940. 

Delorme-Axford E and Klionsky DJ. The LC3-conjugation machinery specifies cargo loading and secretion of extracellular vesicles. Autophagy. 2020 Jul;16(7):1169-71. doi: 10.1080/15548627.2020.1760057.

2019

Delorme-Axford E, Popelka H, Klionsky DJ. TEX264 is a major receptor for mammalian reticulophagy. Autophagy. 2019 Oct;15(10):1677-81. doi: 10.1080/15548627.2019.1646540.

Delorme-Axford E and Klionsky DJ. On the edge of degradation: Autophagy regulation by RNA decay. Wiley Interdisciplinary Reviews RNA. 2019 May;10(3):e1522. doi: 10.1002/wrna.1522. 

Delorme-Axford E and Klionsky DJ. Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain. Autophagy. 2019 Jan;15(1):1-3. doi: 10.1080/15548627.2018.1539585. 

2018

Delorme-Axford E, Abernathy E, Lennemann NJ, Bernard A, Ariosa A, Coyne CB, Kirkegaard K, Klionsky DJ. The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. Autophagy. 2018;14(5):898-912. doi: 10.1080/15548627.2018.1441648. **Selected for journal cover image.

Delorme-Axford E and Klionsky DJ. Transcriptional and post-transcriptional regulation of autophagy in the yeast Saccharomyces cerevisiae. Journal of Biological Chemistry. 2018 Apr 13;293(15):5396-5403. oi: 10.1074/jbc.R117.804641. 

Delorme-Axford E and Klionsky DJ. Secretory autophagy holds the key to lysozyme secretion during bacterial infection of the intestine. Autophagy. 2018;14(3):365-67. doi: 10.1080/15548627.2017.1401425. 

2016

McConkey CA, Delorme-Axford E, Nickerson CA, Kim KS, Sadovsky Y, Boyle JP, Coyne CB. A three-dimensional co-culture system for the modeling of placental syncytiotrophoblast function and microbial resistance. Science Advances. 2016 Mar 4;2(3):e1501462. doi: 10.1126/sciadv.1501462.

Klionsky DJ et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356.

2015

Delorme-Axford E and Klionsky DJ. A missing piece of the puzzle: Atg11 functions as a scaffold to activate Atg1 for selective autophagy. Autophagy. 2015;11(12):2139- 41. doi: 10.1080/15548627.2015.1116672.

Yao Z, Delorme-Axford E, Backues SK, Klionsky DJ. Atg41/Icy2 regulates autophagosome formation. Autophagy. 2015;11(12):2288-99. doi: 10.1080/15548627.2015.1107692.

Bernard A, Jin M, González-Rodríguez P, Füllgrabe J, Delorme-Axford E, Backues SK, Joseph B, Klionsky DJ. Rph1/KDM4 mediates nutrient-limitation signaling that leads to the transcriptional induction of autophagy. Current Biology. 2015 Mar2;25(5):546-55. doi: 10.1016/j.cub.2014.12.049. 

Delorme-Axford E, Guimaraes RS, Reggiori F, Klionsky DJ. The yeast Saccharomyces cerevisiae: an overview of methods to study autophagy progression. Methods. 2015 Mar;75:3-12. doi: 10.1016/j.ymeth.2014.12.008. 

Guimaraes RS, Delorme-Axford E, Klionsky DJ, Reggiori F. Assays for the biochemical and ultrastructural measurement of selective and nonselective types of autophagy in the yeast Saccharomyces cerevisiae. Methods. 2015 Mar;75:141-50. doi: 10.1016/j.ymeth.2014.11.023. 

Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y. Human placental trophoblasts confer resistance to viruses implicated in perinatal infection. American Journal of Obstetrics and Gynecology. 2015 Jan;212(1):71.e1-8. doi: 10.1016/j.ajog.2014.07.060. 

2014

Delorme-Axford E, Morosky S, Bomberger J, Stolz DB, Jackson WT, Coyne CB. BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery. mBio. 2014 Dec 9;5(6):e02147. doi: 10.1128/mBio.02147-14.

Delorme-Axford E, Sadovsky Y, Coyne CB. The placenta as a barrier to viral infections. Annual Review of Virology. 2014 Nov;1(1):133-46. doi: 10.1146/annurev-virology-031413-085524.

2013

Delorme-Axford E, Bayer A, Sadovsky Y, Coyne CB. Autophagy as a mechanism of antiviral defense at the maternal-fetal interface. Autophagy. 2013 Dec;9(12):2173-4. doi: 10.4161/auto.26558. 

Delorme-Axford E, Sadovsky Y, Coyne CB. Lipid-raft- and SRC family kinase-dependent entry of coxsackievirus B into human placental trophoblasts. Journal of Virology. 2013 Aug;87(15):8569-81. doi: 10.1128/JVI.00708-13. 

Delorme-Axford E*, Donker RB*, Mouillet JF, Chu T, Bayer A, Ouyang Y, Wang T, Stolz DB, Sarkar SN, Morelli AE, Sadovsky Y, Coyne CB (*first co-author). Human placental trophoblasts confer viral resistance to recipient cells. Proc Natl Acad Sci U S A.  2013 Jul 16;110(29):12048-53. doi: 10.1073/pnas.1304718110. **Cozzarelli Prize in Biomedical Sciences.

2012

Bozym RA, Delorme-Axford E, Harris K, Morosky S, Ikizler M, Dermody TS, Sarkar SN, Coyne CB. Focal adhesion kinase is a component of RIG-I-like receptor antiviral signaling. Cell Host & Microbe. 2012 Feb 16;11(2):153-66. doi: 10.1016/j.chom.2012.01.008.

2011

Delorme-Axford E and Coyne CB. The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses. 2011 Dec;3(12):2462-77. doi: 10.3390/v3122462. 

Mukherjee A, Morosky SA, Delorme-Axford E, Dybdahl-Sissoko N, Oberste MS, Wang T, Coyne CB. The Coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type interferon and apoptotic signaling. PLoS Pathogens. 2011 Mar;7(3):e1001311. doi: 10.1371/journal.ppat.1001311. 

2008

Cook LB, Delorme-Axford EB, Robinson K. Caveolae as potential mediators of MCH signaling pathways. Biochemical and Biophysical Research Communications. 2008 Oct 31;375(4):592-5. doi: 10.1016/j.bbrc.2008.08.038.