(a) Applying the currently as-developed implantable biodisintegratable hydrogel microelectrode arrays for diagnosis and treatment on various soft organs/tissues, such as brain tissues regarding epilepsy, stroke, or traumatic brain injury; spinal cords regarding paralysis; heart and blood vessels regarding cardiovascular diseases; intestines and stomach regarding digestive system disorders.

(b) Based on (a), while our research effort has so far been focused in developing degradable implanted electronics, we will put emphasis on the clinical translational strategies.

(c) Development of biodisintegratable penetrating electrodes which can be further applied in the deep brain area for investigating more deep brain-related diseases and disorders such as Parkinson’s diseases, Alzheimer's disease, and depression.

(d) Development of ultra-compliant implanted electrodes and integrated circuit system with multi-modals including biochemical sensing, intracranial pressure sensing, programable drug delivery, stem cell delivery, and optogenetic technology.

(e) Development of skin-compliant non-invasive wearable electronic devices using cost-effective and eco-friendly biomaterials/microfabrication process. The types of devices include EEG/ECG/PPG sensors, continuous transdermal/sweat glucose sensors, controlled drug delivery electrode.

(f) Integrating soft materials into the powering and signal processing systems of electronic devices. Before that, finding practical, scalable, and cost-effective connecting methods to overcome the interface mismatch between soft sensor and integrated circuit systems.