Prohibited Substances and Doping Control
Unit 2
Unit 2
How substances become prohibited
For a substance or method to be prohibited, it must meet two of the following three conditions:
1.The substance or method has the potential to enhance, or does enhance performance in sport.
2.The substance or method has the potential to risk the athlete’s health.
3.WADA has determined that the substance or method violates the spirit of sport.
The World Anti-Doping Prohibited List identifies substances and methods that athletes cannot take or use, and presents them in a number of categories.
It is important to understand that the Prohibited List is not exhaustive in that several categories of substances are ‘open’. For example, some categories include ‘other substances with a similar chemical structure or similar biological effect(s)’.
Every year there are hundreds, if not thousands, of new or modified substances developed in laboratories, or new products released onto the market or black market. There are also people willing to push the boundaries with experimental substances and methods which have not been clinically tested or approved for human use.
Athletes are ultimately responsible for any substance found in their bodies, regardless of how it got there. The presence of a prohibited substance may result in an anti-doping rule violation, whether its use was intentional or unintentional. WADA’s advice to athletes and support personnel is to use caution when considering the use of a particular substance or product as it may lead to a possible anti-doping rule violation.
Steroids
Steroids are a class of hormones. Synthetic or man-made steroids are artificially produced substances. They can be taken to artificially boost the growth of muscles.
Health consequences of steroid use include: psychological dependence, increased aggression, mood swings, increased risk of liver disease and cardiovascular disease, high blood pressure, acne, and sexual side effects.
Drugs commonly referred to as steroids can be classified as anabolic (anabolic-androgenic) steroids or corticosteroids.
Corticosteroids, such as cortisone or prednisone, are drugs that doctors often prescribe to help control inflammation in the body. Corticosteroids are not the same as the anabolic steroids that are often linked with illegal use in sports.
Anabolic Steroids
Anabolic steroids (anabolic-androgenic steroids) are synthetic versions of the male hormone testosterone. They are a class of drugs that are legally available only by prescription and are prescribed to treat a variety of conditions that cause a loss of lean muscle mass.
Non-medical use of anabolic steroids is illegal and banned by most major sports organizations.
Anabolic steroids are testosterone derivatives that help the body metabolize ingested proteins and facilitate the synthesis of skeletal muscle. They also delay fatigue and may create a feeling of euphoria.
Anabolic steroids are illegal due to their proven health risks for individuals who take them. As a powerful hormone, they can cause unexpected and unwanted side effects for individuals who abuse them beyond a doctor's prescription.
Side effects of steroids include:
Infertility and impotence in men
Breast development and testicular shrinkage in men
Excessive face and body hair development in women
Deepened voice, menstrual irregularities, and reduced breast size in women
Acne, oily scalp, mood swings, and baldness in both men and women
Increased risk of high cholesterol, liver disease, liver cancer, and heart attack
Steroids Intake
Steroids are taken in either pill form or injections. The most common dosing is done in cycles of weeks or months, with a short break between. This is called "cycling."
"Stacking" refers to the use of several different types of steroids at the same time.
"Pyramiding," involves slowly increasing the number, the amount, or the frequency of steroids to reach a peak and then gradually tapering the amount and frequency of the drug.
Anabolic steroids are sometimes used by bodybuilders, athletes, and sports fanatics to help their muscles grow.
What are synthetic steroids?
a) Naturally occurring hormones
b) Artificially produced substances
c) Vitamins used in sports
d) Herbal supplements
Which of the following is a health consequence of steroid use?
a) Improved immunity
b) Better sleep
c) Increased aggression
d) Faster healing without risks
What is the main difference between corticosteroids and anabolic steroids?
a) Corticosteroids are illegal in sports
b) Corticosteroids are used to build muscle
c) Corticosteroids are prescribed to reduce inflammation
d) Anabolic steroids are used to treat infections
What does the term “stacking” mean?
a) Taking steroids only once
b) Using steroids in pill form
c) Taking breaks between doses
d) Using several different steroids at the same time
What are anabolic steroids?
Why is the non-medical use of anabolic steroids illegal?
List three health risks associated with steroid abuse.
In what forms can steroids be taken?
Corticosteroids and anabolic steroids are the same type of drug.
Anabolic steroids can delay fatigue and create feelings of euphoria.
Steroid use can cause health problems in both men and women.
Cycling refers to increasing steroid doses without taking breaks.
A. Corticosteroids
B. Anabolic steroids
C. Cycling
D. Stacking
E. Pyramiding
___ Gradually increasing and then decreasing steroid dosage
___ Prescribed drugs used to control inflammation
___ Synthetic testosterone used to build muscle
___ Using steroids in repeated periods with breaks
___ Using multiple steroids at the same time
Cannabinoids
Cannabinoids include marijuana, hashish, and related substances. Some athletes take cannabinoids to enhance sensory perception and chemically decrease nervous tension and fear.
A common perception of marijuana is that its use impairs physical activity, including exercise performance.
Marijuana can decrease hand-eye coordination and distort spatial perception, there are other effects that can be performance-enhancing for some athletes and sports disciplines.
Cannabis can cause muscle relaxation and reduce pain during post-workout recovery. It can also decrease anxiety and tension, resulting in better sports performance under pressure. In addition, cannabis can increase focus and risk-taking behaviors, allowing athletes to forget bad falls or previous trauma in sports, and push themselves past those fears in competition.
The use of cannabinoids can result in psychological and physical dependence, including withdrawal symptoms, loss of memory, attention, and motivation, and weakening of the immune system. For long-term use, they can cause respiratory diseases such as bronchitis, lung cancer, and throat cancer.
Which of the following substances is a cannabinoid?
a) Cortisone
b) Testosterone
c) Marijuana
d) Insulin
Why do some athletes take cannabinoids?
a) To increase muscle size
b) To improve heart function
c) To reduce nervous tension and fear
d) To speed up bone healing
Which effect of marijuana can negatively affect sports performance?
a) Increased focus
b) Muscle relaxation
c) Improved recovery
d) Decreased hand-eye coordination
What is one possible long-term health consequence of cannabinoid use?
a) Improved immunity
b) Better lung capacity
c) Reduced anxiety permanently
d) Respiratory diseases
What are cannabinoids - give two examples.
How can cannabis help some athletes perform better under pressure?
Name two negative effects of cannabinoid use on the body or mind.
How can cannabis affect post-workout recovery?
Cannabinoids include marijuana and hashish.
Marijuana always improves physical performance.
Cannabis can reduce pain and anxiety in some athletes.
Long-term use of cannabinoids can weaken the immune system.
A. Muscle relaxation
B. Reduced anxiety
C. Impaired coordination
D. Increased focus and risk-taking
E. Long-term respiratory problems
___ Helps athletes recover after workouts
___ Can distort spatial perception
___ May improve performance under pressure
___ Can push athletes past fear and previous trauma
___ Includes bronchitis and lung cancer
Stimulants
Stimulants include ephedrine, amphetamines, and cocaine. Stimulants can increase alertness, reduce fatigue, activate the cardiovascular system, and change the mood. A variety of stimulants are available over the counter, legally and illegally and they are not intended for healthy athletes. WADA’s prohibited list bans more than 60 stimulants. Stimulants are banned in competition.
The use of stimulants can result in psychological and physical dependence including withdrawal symptoms, increased anxiety and aggression, increased blood pressure, as well as increased and irregular heartbeat. In fact, even at a young age, it can result in a heart attack and a stroke.
Athletes can take stimulants orally or by muscle injection. The injection will guarantee the stimulation for 30 minutes, while the oral intake increases the effect to up to four hours.
Which of the following is an example of a stimulant?
a) Marijuana
b) Ephedrine
c) Cortisone
d) Testosterone
What effect do stimulants have on the body?
a) They reduce heart activity
b) They increase alertness and reduce fatigue
c) They improve immunity
d) They slow down mood changes
How many stimulants are banned by WADA?
a) Fewer than 10
b) About 30
c) More than 60
d) Exactly 100
How long can the effect of orally taken stimulants last?
a) 30 minutes
b) 1 hour
c) 2 hours
d) Up to four hours
Name three stimulants mentioned in the text.
Why are stimulants not intended for healthy athletes?
List three health risks associated with stimulant use.
What are the two ways athletes can take stimulants?
Stimulants can be sold legally or illegally.
Stimulants are allowed during competition.
The use of stimulants can lead to dependence.
Even young athletes can suffer serious heart problems from stimulant use.
A. Stimulants
B. WADA prohibited list
C. Oral intake
D. Injection
E. Side effects
___ Method that increases stimulant effects for up to four hours
___ Includes anxiety, aggression, and irregular heartbeat
___ Substances that increase alertness and reduce fatigue
___ Method that guarantees stimulation for about 30 minutes
___ Official list banning more than 60 stimulants in competition
Blood Doping
Blood doping is the misuse of certain techniques and substances to increase red blood cell mass. This allows the body to transport more oxygen to the muscles, increasing stamina and performance in training and competition.
Because such blood cells carry oxygen from the lungs to the muscles, a higher concentration in the blood can improve an athlete’s aerobic capacity and endurance.
The three widely used types of blood doping are:
blood transfusions
injections of erythropoietin (EPO)
injections of synthetic oxygen carriers
Blood transfusions
Most commonly this involves the removal of two units of the athlete’s blood several weeks prior to competition. The blood is then frozen until 1-2 days before the competition when it is thawed and injected back into the athlete. This is known as autologous blood doping.
Homologous doping is the injection of fresh blood, removed from a second person, straight into the athlete.
EPO
EPO is a hormone that is produced naturally by the human body. EPO stimulates red blood cell production, which improves the amount of oxygen the blood can carry to the muscles. EPO can be taken to artificially boost the effectiveness of performance in training and competition.
The use of EPO can result in increased blood viscosity or thickness and stickiness of the blood, blood clots that prevent the blood flow to the lungs, increased blood pressure and increased risk of heart attack and stroke, and general weakness.
Synthetic Oxygen Carriers
Another method of blood doping involves the use of artificial oxygen carriers. These are chemicals or purified proteins which have the ability to carry oxygen.
They have been developed for therapeutic use, however, are now being misused as performance enhancers.
At the heart of blood doping are endurance sports such as cycling, cross–country skiing, biathlon, triathlon, long–distance races, etc.
What is the main purpose of blood doping?
a) To reduce muscle fatigue permanently
b) To increase red blood cell mass
c) To strengthen bones
d) To speed up recovery from injuries
How does blood doping improve athletic performance?
a) By increasing muscle size
b) By improving coordination
c) By transporting more oxygen to the muscles
d) By reducing heart rate
Which of the following is an example of autologous blood doping?
a) Injecting blood from another person
b) Injecting synthetic oxygen carriers
c) Reinjecting the athlete’s own stored blood
d) Taking EPO tablets
Which sport is most associated with blood doping?
a) Gymnastics
b) Weightlifting
c) Sprinting
d) Cycling
What is blood doping and why do athletes use it?
Name the three widely used types of blood doping.
What is EPO and what effect does it have on the body?
List three health risks linked to the use of EPO.
Blood doping increases the amount of oxygen the blood can carry.
Homologous blood doping uses the athlete’s own blood.
Artificial oxygen carriers were originally developed for medical use.
Blood doping is mainly used in endurance sports.
A. Blood doping
B. Autologous transfusion
C. Homologous transfusion
D. Erythropoietin (EPO)
E. Artificial oxygen carriers
___ Injection of blood taken from another person
___ Hormone that stimulates red blood cell production
___ Misuse of techniques to increase red blood cell mass
___ Reinfusion of the athlete’s own stored blood
___ Substances that chemically carry oxygen
Human Growth Hormone
Some people turn to a substance called Human Growth Hormone (hGH) in hopes that it will keep them feeling and looking youthful.
hGH, produced by the pituitary gland, spurs growth in children and adolescents. It also helps to regulate body fluids, muscle and bone growth, sugar and fat metabolism, and heart function.
Human Growth Hormone (hGH) is produced naturally by the pituitary gland. hGH contributes to the bone, muscle, and organ growth. Dopers take hGH to stimulate muscle growth and boost their athletic performance.
The use of hGH may result in abnormal enlargement of the hands and feet, and growth of the facial bones leading to a protruding forehead, brow, skull, and jaw, severe headaches, loss of vision, high blood pressure, and heart failure, diabetes and tumors, crippling arthritis, heart enlargement, and liver and thyroid damage.
Where is Human Growth Hormone (hGH) produced in the body?
a) The liver
b) The heart
c) The pituitary gland
d) The kidneys
Why do some people and athletes use hGH?
a) To reduce pain
b) To slow heart rate
c) To feel younger and boost performance
d) To improve coordination
What is one normal function of hGH in the body?
a) Improving vision
b) Regulating muscle and bone growth
c) Preventing disease
d) Increasing blood pressure
Which of the following is a possible side effect of hGH abuse?
a) Improved immunity
b) Reduced bone size
c) Enlargement of hands and feet
d) Faster reaction time
What is Human Growth Hormone (hGH) and what gland produces it?
How does hGH normally help the human body?
Why do dopers take hGH?
List three serious health risks linked to the misuse of hGH.
hGH is naturally produced by the human body.
hGH is only important for children and has no effect on adults.
Misuse of hGH can cause serious damage to organs.
hGH abuse can affect bone and facial structure.
A. Pituitary gland
B. hGH
C. Athletic misuse
D. Physical side effects
E. Organ damage
___ Gland that produces Human Growth Hormone
___ Hormone that supports bone, muscle, and organ growth
___ Use of hGH to stimulate muscle growth and performance
___ Includes enlarged hands, feet, and facial bones
___ Includes heart, liver, and thyroid damage
Doping Control
Doping control is an essential part of anti-doping programs to promote and protect the integrity of sport and the health of athletes.
Testing is carried out in accordance with the World Anti-Doping Code and a series of international standards.
The doping control officer, also known as a DCO, plays a major role in protecting your rights in the doping control process, which consists of five phases: athlete selection, athlete notification, sample collection, sample analysis, and results management.
How can you be selected for testing? Testing can be conducted in two situations – in competition and out of competition. For in-competition testing, the selection may occur in a number of ways, including: by random selection, based on finishing position, or by targeting for a particular reason. For out-of-competition testing, you can be tested anytime and anywhere with no advance notice.
If you’ve been identified in the Register Testing Pool, you’ll be required to provide whereabouts information. You may be tested at home, at your training location, or other relevant locations.
How will you be notified? The notification process is the same for both in- and out-of-competition testing. If you’re selected for testing, the chaperone will show you their DCO accreditation to demonstrate that they are authorized to conduct testing. They will also explain your rights and responsibilities in the doping control process and ask you to sign a form. Once you’ve been notified, you must report immediately to the doping control station. You may request a delay for valid reason such as: you’re taking part in a medal ceremony, you must attend a press conference, you require medical treatment.
Upon notification, a DCO or chaperone will stay at your side at all times until the testing process has been completed.
What is the sample collection process?
During this process, you also have specific rights, such as having a representative with you, as well as certain responsibilities. The chaperone will first ask you for a valid photo ID to confirm your identity. You’ll be asked to provide one or more urine samples and/or blood samples. When you’re ready to provide a urine sample, a doping control official of the same gender as you will witness the passing of the sample and will stay with you until you provide a sample that meets all requirements. You will then be asked to divide the urine sample into B and A bottles and then seal them. Throughout the process, you will be the only one to handle the sample collection equipment unless you require assistance. Finally, you’ll be asked to review and sign the doping control form. The samples and the copy of the form that does not disclose your identity will be sent to a WADA-accredited laboratory, while the other copies will go to the other relevant doping organizations. A copy of the form will also be provided to you.
How are the samples analyzed?
Once your sample arrives at the laboratory, it will be opened and analyzed. The B sample will be securely stored. Should the A sample reveal adverse analytical findings, the B sample will be analyzed to confirm the result.
How are the results managed?
The lab will report the results to the anti-doping organization, responsible for results management. A copy will be sent to WADA to ensure the accountability of the process. In the event of adverse analytical findings, your rights include requesting and attending the B sample analysis within set deadlines, a fair hearing, and the right to appeal.
As an essential deterrent, a standard doping control process across all countries helps protect the right of athletes to compete on a level plane field in the true spirit of sport.
The Stages of Doping Control
Doping Control – Your urine and/or blood can be collected anytime and anywhere for doping control.
Athlete Selection – You will be notified by a doping control officer (DCO) or chaperone about your selection for doping control. You will be asked to sign a form confirming that you understand your rights and responsibilities.
Report Station – You will report to the doping control station as soon as possible.
Choose vessel – You will choose a collection vessel from the selection provided.
Provide Sample – A minimum amount of 90 ml of urine will need to be provided. You will disrobe from knees to navel and from your hands to elbow to provide a clear view of the passing of the sample. A DCO or a chaperone of the same gender will observe the urine leaving your body.
Split the Sample – Choose a sample collection kit from the selection provided. Split the sample in the A and B bottles. Pour urine up to the line in the B bottle first. Next, fill the A bottle and leave a small portion in the collection vessel.
Seal the Sample – Seal the A and B bottles.
Specific Gravity – The DCO will measure the specific gravity of the sample to ensure it is not too diluted to analyze. If it is too dilute, you may be required to provide additional samples.
Sign the Form – You will complete the doping control form by: providing personal information; noting any substances you may be taking: prescription medication, over the counter medication and supplements; noting concerns and comments, if you have any, about the doping control; confirming the information, recorded numbers and sample code are correct; signing and receiving your copy of the doping control form.
Sample Analysis – Samples will be sent to a WADA accredited laboratory in strict confidentiality. Your A sample will be analyzed and your B sample will be securely stored for further testing if required. The laboratory will send the results to the responsible anti-doping organization (ADO) and WADA.
Athlete's Rights and Responsibilities
Athlete's Rights
You have the right to:
- have a representative and, if available, an interpreter;
- ask for additional information about the sample collection process;
- request a delay in reporting to the Doping Control Station for valid reasons;
- if you are an athlete with a disability, to request modifications to the sample collection procedure
Athlete's Responsibilities
You have a responsibility to:
- remain within the direct observation of the DCO/chaperone at all times from the point of notification until the completion of the sample collection process;
- produce appropriate identification;
- comply with sample collection procedures (failure to do so is an anti-doping rule violation);
- report immediately for doping control, unless there are serious reasons for the delay