Research Area
•Natural products driven medicinal chemistry, Metabolic Dysfunction-Associated Diseases.
•Extraction, isolation and structure elucidation of pure molecules from natural sources by using different chromatographic and spectroscopic techniques, qualitative and quantitative analysis of natural products by HPLC, preparation of enriched and standardized fraction based on marker compounds, as well as interpretation of NMR spectra (1H, 13C, HSQC, COSY, HMBC, NOESY etc), LC-MS/MS, GC-MS, FTIR for structure elucidation of small molecules.
• Work is focused on translational research towards the development of phytopharmaceuticals and ASU drug and/or lead molecules from ethno-medicinal plants for treatment of Metabolic Dysfunction-associated Diseases with special emphasis on diabetes, MASH, WAT Browning (UCP1) and diabetic nephropathy (developing SGLT2 inhibitors) followed by study of underlying mechanism of action.
•Regulatory for herbals and phytopharmaceuticals: cGMP, QCQA and drug testing (Herbals & Phytopharmaceuticals).
Our group is working on preclinical evaluation of selected medicinal plants based on Indian Systems of Medicine (ISM) used for the treatment of Metabolic Dysfunction-Associated Diseases with an aimed for the development of phytopharmaceuticals and ASU drugs.