Publications

Research papers

1. Kar R, Chattopadhyay S, Sharma A, Sharma K, Sinha S, Arimbasseri GA, and Patil VS,  2024. Single-cell transcriptomic and T cell antigen receptor analysis of human cytomegalovirus (hCMV)-specific memory T cells reveals effectors and pre-effectors of CD8+- and CD4+-cytotoxic T cells. Immunology.172 (3); 420-439. DOI: https://doi.org/10.1111/imm.13783

2. Yadav P, Rana K, Nardini V, Khan A, Pani T, Kar A, Jain D, Chakraborty R, Singh R, Jha SK, Mehta D, Sharma H, Sharma RD, Deo SVS , Sengupta S, Patil VS, Faccioli LH, Dasgupta U, Bajaj A, 2024. Engineered nanomicelles inhibit the tumour progression via abrogating the prostaglandin-mediated immunosuppression. Journal of Controlled Release 368, 548-565

3. Kar A, Jain D, Kumar S, Rajput K, Pal S, Rana K, Kar R, Jha Sk, Medatwal N, Yavvari PS, Pandey N, Mehta D, Sharma S, Bhattacharya D, Pradhan MK, Sharma RD, Srivastava A, Agrawal U, Mukhopadhyay A, Sengupta S, Patil VS, Bajaj A, Dasgupta U, 2023,  A localized hydrogel-mediated chemotherapy causes immunogenic cell death via activation of ceramide-mediated unfolded protein response. Science Advances 9 (26), eadf2746 . DOI: 10.1126/sciadv.adf2746 

4. Verma P, Arora A, Rana K, Mehta D, Kar R, Verma V, Srikanth CV, Patil VS, Bajaj A, 2022, Gemini lipid nanoparticle (GLNP)-mediated oral delivery of TNF-α siRNA mitigates gut inflammation via inhibiting the differentiation of CD4+ T cells. Nanoscale,  14(39), 14717-14731 

5. Rana K, Pani T, Jha SK, Mehta D, Yadav P, Jain D, Pradhan MK, Mishra S, Kar R, Reshma GB, Srivastava A, Dasgupta U, Patil VS*, and Bajaj A*, 2022, Hydrogel-mediated Topical Delivery of Steroids Can Effectively Alleviate Psoriasis via Attenuating the Autoimmune Responses. Nanoscale  https://doi.org/10.1039/D1NR06001E. *co-corresponding author

6. Kumar S, Pal S, Thakur J, Rani P, Rana K, Kar A, Kar R, Mehta D, Jha SM, Pradhan MS, Jain D, Rajput K, Mishra S, Ganguli M, Srivastava A, Dasgupta U, Patil VS, Bajaj A. 2021. Nonimmunogenic Hydrogel-Mediated Delivery of Antibiotics Outperforms Clinically Used Formulations in Mitigating Wound Infections ACS Applied Materials & Interfaces.

7. Pal S, Soni V, Kumar S, Jha SM, Medatwal N, Rana K, Yadav P, Mehta D, Jain D, Sharma P, Kar R, Srivastava A, Patil VS, Dasgupta U, Nandicoori VK, Bajaj A. 2021. A hydrogel-based implantable multidrug antitubercular formulation outperforms oral delivery. Nanoscale, 13 (31), 13225-13230.

8.  *Zhang Q, *ChaoT, *Patil VS, Qin Y , Tiwari SK , Chiou J , Dobin A, Tsai C, Li1 Z , Dang J , Gupta S, Urdah K , Nizet V, Gingeras TR, Gaulton K and Rana TM. 2019. The long noncoding RNA ROCKI regulates inflammatory gene expression.  The Embo J  38:e100041/2019 (*Joint 1st author) .

9. Patil VS, Madrigal A, Schmiedel BJ, Clarke J, O'Rourke P, deSilva AD, Harris E, Peters B, Seumois G, Weiskopf D, Sette A and Vijayanand P, 2018. Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis. Science Immunology 3, eaan8664 (2018). (featured article rotate).

10. Tian Y, Babor M, Lane J, Schulten V, Patil VS, Seumois G, Burel J, De Silva AD, Premawansa S, Premawansa G, Wijewickrama A, Vijayanand P, Weiskopf D, Sette A, Peters B. 2017. Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA. Nature Communications 8, 1473 (DOI: 10.1038/s41467-017-01728-5).

11. Dang J, Tiwari, SK, Gianluigi Lichinchi, Yue Qin, Patil VS, Alexey M. Eroshkin, and Tariq M. Rana. 2016. Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3. Cell Stem Cell 19, 1–8, July 7, 2016.

12. *Patil VS,*Anand A, Chakrabarti A, and Kai T. 2014. The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster. BMC Biology, 12:61 (*Joint 1st author). Comments in: Yang Z and Pillai RS. 2014. Fly piRNA biogenesis: tap dancing with Tej. BMC Biology, 12:77.

13. *Sakurai K, *Talukdar I, *Patil VS, Dang J, Li Z, Chang KY, Lu CC, Delorme-Walker V, Dermardirossian C, Anderson K, Hanein D, Yang CS, Wu D, Liu Y, Rana TM. 2014. Kinome-wide functional analysis highlights the role of cytoskeletal remodeling in somatic cell reprogramming. Cell Stem Cell. 2014;14(4):523-34 (*Joint 1st author). Comments in: David L, Hirsch CL. 2014. How Tets and cytoskeleton dynamics MET in reprogramming. Cell Stem Cell. 2014 Apr 3;14(4):417-8.

14. Li Z, Chao TC, Chang KY, Lin N, Patil VS, Shimizu C, Head SR, Burns JC, Rana TM. 2014. The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proc Natl Acad Sci U S A. Jan 21;111(3):1002-7. 

15. Patil VS and Kai, T. 2010. Repression of Retroelements in the Drosophila Germline via piRNA Pathway by the Tudor Domain Protein Tejas. Current Biology 20: 734-730.

Reviews

1. Patil VS, Zhou R, Rana TM. 2014. Gene regulation by non-coding RNAs. Crit Rev Biochem Mol Biol. Jan-Feb;49(1):16-32. 

2. *Pek, JW, *Patil VS and Kai, T. 2012. piRNA pathway and the potential processing site the nuage, in the Drosophila germline. Develop. Growth Differ. 54, 66–77. (*Joint 1st author).