Feasibility
Studies currently in Feasibility
Studies currently in Feasibility
Last content update - 27th April 2026
Please contact the Cancer Research Team for more information
All Specialties
BLADDER
BREAST
COLORECTAL
GYNAE
Specialty: Gynae
PI: Prof. Dennis Hadjiyiannakis
CPMS No: 68839
Estimated Opening: April 2026
Description: A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment With or Without Bevacizumab Versus Standard of Care After Second-line Platinum-based Doublet Chemotherapy in Participants With Platinum-sensitive Recurrent Ovarian Cancer (TroFuse-022/ENGOT-ov84/GOG-3103)
Specialty: Gynae
PI: Prof. Dennis Hadjiyiannakis
CPMS No: 72651
Estimated Opening: June 2026
Description: A Phase I/Ib, Multi-centre, Open-label Study to Evaluate the Safety, Tolerability, and Immunogenicity of Cryptivax-1001, a mRNA Lipid Nanoparticle Therapeutic Cancer Vaccine, in Participants with FIGO Stage III–IV High-Grade Serous or Predominantly Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Following Optimal Primary/Interval Debulking Surgery and First-Line Platinum-Based Chemotherapy (OVACT Study)
Head & Neck
Lung
Specialty: Lung
PI: Dr Sin Lau
CPMS No: 66899
Estimated Opening: May/June 2026
Description: A Phase Ib/II, multi-site, open-label, three-part trial to evaluate the efficacy, safety, pharmacokinetics, and recommended combination dose of BNT324 with BNT327 in participants with advanced lung cancer
Multiple Specialties
Specialty: Multiple
PI: n/a (PIC site)
IRAS No: 355684
Estimated Opening: Summer 2026
Description: Chemotherapy-Induced Hearing Loss and Health Inequality
PROSTATE
Speciality: Prostate
PI: Mr Michal Smolski
CPMS No: 63289
Estimated Opening: TBC 2026
Description: A randomised controlled trial comparing the clinical and cost-effectiveness of lymph node removal in patients undergoing curative surgery for localised high-risk Prostate Cancer.
RADIOTHERAPY
RENAL
Speciality: Renal
PI: Dr Natalie Charnley
CPMS No: 69744
Estimated Opening: April 2026
Description: Acrus Phase 3 ccRCC study: PEAK-1 will be a double-blind study investigating Casdatifan (AB521; HIF-2α inhibitor) in combination with cabozantinib (cabo) vs. placebo + cabo in patients with advanced or metastatic ccRCC whose cancer has progressed following prior anti-PD-1/PD-L1 therapy.
SKIN
Supportive and Palliative Care
Teens & Young Adults (TYA)
UPPER GI
Specialty: Upper GI
PI: Dr Catherine Mitchell
IRAS: 329646
Estimated Opening: May 2026
Description: A Randomised Phase 2 Trial Comparing Proton versus Photon Based Neoadjuvant Chemoradiation, followed by Adjuvant Immunotherapy, in Oesophageal Cancer.