Providing excellence in clinical research delivery
Providing excellence in clinical research delivery
The National Institute for Health and Care Research (NIHR) Sheffield Clinical Research Facility (CRF) is part of the NIHR and hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with the University of Sheffield.
The NIHR funds, enables and delivers world-leading health and social care research that improves people’s health and wellbeing and promotes economic growth.
NIHR Clinical Research Facilities (CRFs) are purpose-built facilities in NHS hospitals where researchers can conduct studies. The NIHR has awarded £161 million over 5 years to 28 CRF facilities across England, to support early-phase and complex studies.
In 2022, the NIHR Sheffield CRF was awarded £7.9m in funding which will support the development and testing of new treatments for diseases, many of which currently have no cure. This funding award covers 2022 to 2027.
News & events
An innovative trial of a 'pill-on-a-thread' test which could lead to a new screening programme for oesophageal cancer has arrived in Sheffield.
The BEST4 Screening trial will find out if a new ‘pill-on-a-thread’ test could be used to screen people with heartburn for Barrett’s oesophagus – a condition that can lead to oesophageal cancer.
The trial is being led in Sheffield by Gastroenterology Consultant Professor Andrew Hopper and is backed by £6.4 million of funding from Cancer Research UK and the National Institute for Health and Care Research (NIHR).
For more information please visit the Sheffield Teaching Hospitals news page.
(August 2025)
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