DASGUPTA LABORATORY

Recreating the lost RNA World of primordial life

 Illuminating the hidden RNA World of modern life

The DasGupta Laboratory opened its doors in March 2024. 

We aspire to be a vibrant group driven by curiosity and camaraderie. Together we will take on some of science's hardest but foundational questions such as:

How did life emerge 4 billion years ago?   How can we make chemical systems evolve?  What are the structural principles underlying catalytic function in the earliest enzymes made of RNA? How do RNA enzymes acquire new functions through evolutionary adaptation?

We won't just look at the past, we will also look into the future. 

Using evolutionary approaches, we will develop new technologies to investigate poorly understood areas of RNA Biology. Initially, we will focus on RNAs with terminal modifications.

We are excited about all things RNA (and nucleic acids) - so bring your own ideas, and let's explore!