Welcome to the Zhang Group
We comprise a diverse team of professionals spanning chemistry, chemical engineering, materials science, veterinary medicine, and clinical practice.
Our primary focus lies in the development of stimuli-responsive hydrogels (bio-adhesive), targeted drug delivery systems, and portable devices aimed at tackling critical biomedical challenges that play critical roles in human life.
Bio-Adhesive
Nature Communications. 2021, 12, 1670
Precision Drug Delivery
U.S. Provisional Patent Application No. 62/848,432
Biomedical Device
Advanced Science. 2023, 2203943
Targeted Challenges
Skin Problem
GI Issue
Lung Disease
Cancer
Our research accomplishments include a timed delayed pulsatile drug delivery system for scarless wound healing, a fluorescent nanodiamond based portable sensor for long-term continuous blood glucose monitoring, multi-responsive nanoparticles for drug delivery, and a novel nano-composite bio-scaffold. We will continuously develop novel hydrogels, nanoparticles and devices to address biomedical problems that can result in treatment failures and adverse effects.
Research Philosophy
To anticipate the in vivo efficacy of our innovations, we prioritize initial experimentation with predictive in vitro models, such as organoid systems, to analyze and refine our methodologies. Subsequently, we engage with a variety of animal models, ranging from small to large, to corroborate our research strategies and evaluate treatment outcomes. Additionally, we collaborate with bioinformatics experts and data analysts to comprehensively analyze data, forecast outcomes, and optimize our approach.
Our laboratory's overarching objective is to translate our research discoveries into clinical trials, ultimately contributing to advancements in both human and animal healthcare.
