Conference Program

Conference Program Booklet Download

Monday 15th May 2023

3pm-5pm Registration open 

Martin Lackmann Award for Translational Research

5.00pm Welcome and award presentation

Award plenary lecture

6.30pm Pre-dinner drinks

7.30pm Conference Dinner

Tuesday 16th May 2023

8.30am Scientific program opening address

Session 1: Signalling Pathways in Cancer

8.45am-10.30am 

Chair: Wayne Phillips, Peter MacCallum Cancer Centre, Melbourne

Bart Vanhaesebroeck University College London, United Kingdom

‘In search of novel ways to modulate the PI3K pathway for therapeutic benefit’

Kieran Harvey Monash University/Peter MacCallum Cancer Centre, Melbourne

‘A new subcellular location for Hippo signalling and its role in organogenesis’

Sabryn Hamila Monash University, Melbourne (Short talk selected from abstract)

‘A PI3K signalling regulator that promotes breast cancer-derived exosome release’

Andrew Cox Peter MacCallum Cancer Centre, Melbourne 

‘The Keap1-Nrf2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis’

10.30am-11.00am Morning tea

Session 2: Immunotherapies

11.00am-12.30pm

Chair: Mireille Lahoud, Monash University

Meredith O'Keeffe Monash University, Melbourne

‘Targeted kinase inhibitors affect dendritic cell function - with major differences from mouse to man’

Diego Chacon-Fajardo Garvan Institute of Medical Research, NSW (Short talk selected from abstracts)

‘Re-purposing Non-oncology Agent Itraconazole to Target the Dynamic Cellular Ecosystem of Pancreatic Cancer’

Misty Jenkins Walter and Eliza Hall Institute, Melbourne

‘Phosphoproteomic analysis of second generation chimeric antigen receptor signalling for the treatment of glioblastoma’

Maria Tanzer Walter and Eliza Hall Institute/MPIB (Short talk selected from abstract)

‘A proteomic perspective on signalling mechanisms of dead cell removal’

12.30pm-1.30pm Lunch

Session 3: Translational - Precision Oncology

1.30pm-3.15pm

Chair: Thierry Jardé, Monash University

Ron Firestein Hudson Institute, Melbourne 

‘Childhood Cancer Model Atlas’

Luc Furic Peter MacCallum Cancer Centre, Melbourne

‘PMR-116, a second generation RNA Pol I inhibitor’ 

Jaclyn Sceneay Biocurate Pty. Ltd

‘BioCurate –accelerating the translation and commercialisation of novel therapies’ 

Heather Murray Hunter Medical Research Institute, NSW (Short talk selected from abstracts)

‘Phospho-proteogenomic profiling of acute myeloid leukaemia uncovers novel therapeutic targets’

Dustin Flanagan Monash University, Melbourne 

‘Epithelial TGFβ moonlights as a bad actor in colorectal cancer’

3.15pm-3.45pm Afternoon Tea

Session 4: Paediatric Cancer

3.45pm-5.50pm

Chair: Jason Cain, Hudson Institute, Monash University

Paolo Salomoni German Center for Neurodegenerative Diseases (DZNE), Helmholtz

‘Investigating the Role of Onco-Histones and their Partners in Crime’

Emmy Fleuren Children's Cancer Institute, New South Wales

‘Multi-platform tyrosine kinase profiling reveals novel, actionable kinase expression signatures in paediatric sarcoma’

Raelene Endersby Telethon Kids Institute, Western Australia

‘Therapeutic targeting of the DNA damage response pathway enhances treatment efficacy in medulloblastoma’

Ruth Palmer Sahlgrenska Academy, Gothenburg University, Sweden

‘Regulation of ALK signaling pathways and therapeutic implications for neuroblastoma’

6.30pm Poster Session and pre-dinner drinks

7.30pm Social Dinner

Wednesday 17th May 2023

8.30am Announcement of poster awards

Session 5: Systems Biology

8.45am-10.30am

Chair: James Burchfield, Charles Perkins Centre, The University of Sydney

Mariko Okada Osaka University, Japan

'Encoding and decoding of NFBk transcriptional regulation'

David Croucher Garvan Institute of Medical Research, NSW

'Memory of stochastic single-cell apoptotic signalling promotes chemoresistance in neuroblastoma'

Sungyoung Shin Monash University (Short talk selected from abstracts)

'Integrated analyses prioritize therapies for PIK3CA-mutant breast cancer and reveal a pro-survival role for p21 in drug resistance'

Sean Humphrey Murdoch Children's Research Institute, Melbourne

'(de)coding functional signal transduction'

10.30am-11.00am Morning tea

Session 6: Emerging Technologies

11.00am-12.30pm

Chair: Sefi Rosenbluh, Monash University

Travis Ruan Garvan Institute of Medical Research, NSW

‘Targeting stromal cells to reverse immune suppression in human triple negative breast cancer’

Susan Woods SAHMRI, South Australia

‘Developing engineered bacteria for tumour detection and treatment’

Charlene Lam Monash University (Short talk selected from abstracts)

‘Novel Immediate Direct Targets of EPO Signalling in Human Erythropoiesis’

Paul Timpson Garvan Institute of Medical Research, NSW

‘Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status’

12.30pm-1.30pm Lunch

Session 7 Tumour Evolution

1.30pm-3.30pm

Chair: Margaret Centenera, South Australian Health and Medical Research Institute

Ramanuj Dasgupta ASTAR, Singapore

“Fetal echoes” in inflammatory liver disease and cancer

Delphine Merino Olivia Newton-John Cancer Research Institute, Victoria

TBA

Liz Caldon Garvan Institute of Medical Research, NSW (Short talk selected from abstracts)

‘Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of the P-Rex1/Rac1 signalling axis’

Charles Swanton Francis Crick Institute, UK

‘Mechanism of Action and Inflammatory Axis for Air Pollution Induced Non-Small Cell Lung Cancer’

3.30pm Thanks and farewell