The instruction manual follows some principals of UDL as well as AEM. In terms of UDL, the instructions allow players choice- they can choose what color DNA player pawn they would like to use throughout the game. Players are also able to pick the individual gene they are trying to synthesis into a protein. There are also varying degrees of difficulty for the ?? Transcription cards that players can choose from. In terms of AEM instructions is typed in high-contrast fonts with accessible font sizes. There are clear visuals associated with each component of the game as well which could assist not only visually impaired, but also ESL students. The game board and rule book layout are designed for easy understanding and navigation, with clearly defined sections. The instructions are also linked as a google document which could easily be translated into a different language for the ESL students. The game design minimizes the need for complex physical dexterity. Simple game mechanics ensure that players with motor difficulties can participate fully. Adaptations like push-button dice rollers or card turners can be used. Game instructions and text use plain language to ensure understandability across age groups and cognitive abilities. Game tasks and instructions are organized in a logical, sequential manner that builds on previous knowledge, aiding in cognitive processing and learning.