Research

Currently, people are encountering with significant healthcare challenges. Advances in molecular biology have provided us with a deeper comprehension of the intricate molecular processes that influence human health and contribute to various diseases. Our research primarily focuses on molecular biomarkers associated with different diseases, notably cancer and infectious diseases. 

Our investigation includes the identification and characterization of genes/proteins that potentially wield important roles in diverse diseases. Furthermore, we delve into the exploration of multidrug resistance mechanisms within both cancer and infectious diseases. In practical terms, our work involves the development of applications that encompass the identification and characterization of drug targets, as well as the identification of proteins for diagnostic and prognostic applications.

Cancer Biomarkers

In the post-genomic era, omics techniques have emerged as vital tools in identifying biomarkers associated with the development of various cancers and infectious diseases. Our research is centered on the search for molecular biomarkers that drive the progression of specific diseases, particularly nasopharyngeal carcinoma and cholangiocarcinoma, which are prevalent in Thailand. Utilizing a range of omics methodologies, our investigation aims to uncover potential biomarkers, subjecting them to thorough validation at the levels of molecules, cells, and organisms. The biomarkers identified through our comprehensive research hold the potential to unravel the complex mechanisms behind disease development, offering valuable insights into molecular targets that could significantly improve the accuracy of diagnosis, the precision of prognosis, and the effectiveness of treatment strategies within the clinical domain.

AMR: a case of Clostridioides difficile 

The burden of antimicrobial resistance (AMR) is rising significantly in Asia and worldwide. The impact of resistance is immense, characterized by increased cost, length of hospital stays and mortality. East and Southeast Asia, including Thailand are particularly important as they are regarded as a high-risk region for the emergence and dissemination of AMR. Each year, increasing numbers of people are infected with AMR pathogens, causing a great deal of socioeconomic loss. Therefore, there is an urgent and overwhelming need to establish a forefront research focused upon finding alternative approaches to tackle AMR. Our research will deliver alternative, non-antibiotic therapies to combat AMR pathogens, focusing on an urgent threat Clostridioides difficile. Replacing antibiotics with alternative products promises to delay the resistance and restore the activity of antibiotics that are no longer effective due to resistance.

AgriTech research

Innovation, research, and development stand as pivotal drivers for the ongoing success of not only our country's food and agriculture industries but also those extending to global horizons. Recently, we secured funding earmarked for the advancement of high-value AgriTech products. The central goal of our research collective is to shape the future trajectory of food and agriculture systems, an ambition we pursue through an integrated and multidisciplinary approach. This concerted effort ensures that our discoveries seamlessly transition into practical applications. At present, our focus revolves around two key areas: the refinement of valuable commodities derived from agricultural byproducts and the cultivation of cultured meat, both representing pivotal endeavors in our pursuit of innovation.


Funding supports