Relevant Articles

Written by Nobel Prize Winner Eric Kandel, this review provides a great overview of the biological and mechanical processes behind the formation of memories in the mammalian brain. 

Kandel, E. R.; Dudai, Y.; Mayford M. R. The Molecular and Systems Biology of Memory. Vol 157,1 (2014). 163-186. doi:https://doi.org/10.1016/j.cell.2014.03.001. 

This review outlines general plasticity in the hippocampus and the process of tagging. This forms the framework of synaptic interactions in different scenarios, and it explains the underlying cellular mechanisms enabling the linking of short- and long-term memories over time.

Bin Ibrahim, M. Z.; Benoy, A.; Sajikumar, S. Long-term plasticity in the hippocampus: maintaining within and 'tagging' between synapses.” The FEBS journal vol. 289,8 (2022): 2176-2201. doi:10.1111/febs.16065.

This overview by Eric Klann outlines the role of protein synthesis in memory formation, specifically regarding long-term memory.  It also gives a detailed description of the consolidation of memory, a critical step in long-term memory formation. 

Klann, E. R.; J David S. Altered protein synthesis is a trigger for long-term memory formation. Neurobiology of learning and memory vol. 89,3 (2008): 247-59. doi:10.1016/j.nlm.2007.08.009.

This paper by Michael A. Sutton looks at translation in the dendrites of neurons themselves and explores their critical role in learning and memory. 

Sutton, M. A.; Schuman, E. M. Dendritic protein synthesis, synaptic plasticity, and memory. Vol. 127,1 (October 06, 2006): 49-58. doi: https://doi.org/10.1016/j.cell.2006.09.014.