Kinomica offers KinoScan™, a powerful combination of advanced proprietary bioinformatics and LC-MS/MS phospho-proteomics to investigate global cellular signalling activities and reprogramming of biochemical network circuitries, for a range of applications, including:
- Basic Research
- determination of disease mechanisms
- improve drug target & biomarker identification
- Drug Discovery
- improved monitoring of drug molecular efficacy and response (i.e. reveal mode of action / identify mechanism of resistance) in preclinical models
- improve compound selection and optimisation at preclinical stage, to de-risk downstream therapeutic R&D pipelines
- Drug Development & Post Launch
- improved monitoring of drug molecular efficacy and response (i.e. reveal mode of action / identify mechanism of resistance) in human tissue / biopsies
- discover & validate appropriate patient selection biomarkers for companion diagnostics
- identify likely responders to therapy / improve and enhance patient stratification