Publications
RESEARCH PUBLICATIONS: Peer-reviewed Original Science Research
Obulapathi Ummadisetty, Anagha Gadepalli, Deepak Chouhan, Vinod Tiwari*. Development and validation of clinically Mimicable model of frostbite injury-induced chronic pain. Cellular Signalling 2024, p.111028. (Impact Factor- 4.31) *CORRESPONDING AUTHOR
Anagha Gadepalli, Obulapathi Ummadisetty, Akhilesh, Deepak Chouhan, Krushna Eknath Yadav, Vinod Tiwari* Peripheral Mu-Opioid Receptor Activation by Dermorphin [D-Arg2, Lys4] (1-4) Amide Alleviates Behavioral and Neurobiological Aberrations in Rat Model of Chemotherapy-Induced Neuropathic Pain, Neurotherapeutics (Just accepted) (Impact Factor- 5.7) *CORRESPONDING AUTHOR
Akhilesh, Deepak Chouhan, Obulapathi Ummadisetty, Nivedita Verma, Vinod Tiwari* Bergenin ameliorates chemotherapy-induced neuropathic pain in rats by modulating TRPA1/TRPV1/NR2B signalling. International Immunopharmacology 2023. (Impact Factor- 5.714) *CORRESPONDING AUTHOR
Kanchan Bharti, Deepika Manish Kumar, Abhishek Jha, Manjit, Akhilesh, Vinod Tiwari, Vikas Kumar, Brahmeshwar Mishra, Development and Evaluation of Amorphous Solid Dispersion of Riluzole with PBPK Model to Simulate the Pharmacokinetic Profile, AAPS PharmSciTech 2023, (Just accepted) (Impact Factor- 4)
Akhilesh, Uniyal A, Mehta A, Tiwari V*. Combined chemotherapy in rodents: A novel model for chemotherapy induced neuropathic pain and pharmacological screening. Metabolic Brain Disease 2023 (Just accepted) (Impact Factor- 3.965) ISSN: 1573-7365. *CORRESPONDING AUTHOR
Gadepalli, Anagha, Obulapathi Ummadisetty, Deepak Chouhan, and Vinod Tiwari*. "Loperamide, a peripheral Mu-Opioid receptor agonist, attenuates chemotherapy-induced neuropathic pain in rats." International Immunopharmacology 124 (2023): 110944. *CORRESPONDING AUTHOR
Shivani Jaiswal, Akhilesh, Vinod Tiwari, Senthil Raja Ayyannan. Anti-nociceptive potential of an isatin-derived dual fatty acid amide hydrolase-monoacylglycerol lipase inhibitor. Pharmacological Reports 2023 (Impact Factor- 4.4)
Waiker D K, Verma A, Akhilesh, Singh N, Roy A, Dilnashin H, Tiwari V, Kumar S T, Singh SP, Krishnamurthy S, Lama P, Vincent Jo D, Shrivastava S K *. Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands for Alzheimer’s Disease Therapy. ACS Chemical Neuroscience 2023 May 22, 2023 (Impact Factor- 5.780) ISSN: 1948-7193.
Namrata Prajapati, Dilip Sharma, Pankaj Ashok Bidve, Akhilesh, Deepak Chouhan, Meghana Allani, Sagarkumar Patel, Moumita Ghosh Chowdhury, Amit Shard, Tiwari V* Glucose Regulation by Newly Synthesized Boronic Acid Functionalized Molecules as Dipeptidyl Peptidase IV Inhibitor: A Potential Compound for Therapeutic Intervention in Hyperglycemia. J Biomol Struct Dyn. 2023 Just accepted (Impact Factor- 3.549) ISSN: 1538-0254. *CORRESPONDING AUTHOR
Jaiswal S, Akhilesh, Tiwari V, Ayyannan SR. Anti-nociceptive potential of an isatin-derived dual fatty acid amide hydrolase-monoacylglycerol lipase inhibitor. Pharmacological Reports 2023 Mar 13:1-9. (Impact factor: 3.9) ISSN: 2299-5684.
Jaiswal S, Akhilesh, Uniyal A, Tiwari V, and Ayyannan Raja S. Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. Bioorganic & Medicinal Chemistry 2022 (60): 116698. (Impact factor: 3.641) ISSN: 0968-0896.
Uniyal A, Akhilesh, Rathore AS, Keshri PS, Singh SP, Singh S, Tiwari V*. Inhibition of Pan-Aurora Kinase Attenuates Evoked and Ongoing Pain in Nerve Injured Rats via Regulating KIF17-NR2B Mediated Signaling. International Immunopharmacology 2022 (Impact Factor- 4.93) ISSN: 1567-5769. *CORRESPONDING AUTHOR
Uniyal A, Gadepalli A, Modi A, Tiwari V*. Modulation of KIF-17/NR2B Crosstalk by Tozasertib Attenuates Inflammatory Pain in Rats. Inflammopharmacology 2022. (Impact Factor- 4.47) ISSN: 1568-5608. *CORRESPONDING AUTHOR.
Kumar A, Kumar B, Kumar R, Kumar A, Singh M, Tiwari V, Trigunayat A, Paul P, Singh P. Acute and subacute toxicity study of ethanolic extract of Calotropis procera (Aiton) Dryand flower in Swiss albino mice. Phytomedicine Plus 2022 2(2): 100224. (5.34) ISSN: 2667-0313.
Akhilesh, Baidya ATK, Uniyal A, Das B, Kumar R, Tiwari V*. Structure-based virtual screening and molecular dynamics simulation for the identification of sphingosine kinase-2 inhibitors as potential analgesics. J Biomol Struct Dyn. 2021 Sep 14:1-19. (Impact Factor- 3.549) ISSN: 1538-0254. *CORRESPONDING AUTHOR
Uniyal A, Akhilesh, Tiwari V, Gadepalli A, Obulapathi U, Tiwari V*. Epigallocatechin-3-gallate Improves Chronic Alcohol-Induced Cognitive Dysfunction in Rats by Interfering with Neuro-inflammatory, Cell Death and Oxido-nitrosative Cascade. Metabolic Brain Disease 2021 Aug 12. (Impact Factor- 3.584) ISSN: 1573-7365. *CORRESPONDING AUTHOR
Uniyal A, Shantanu PA, Vaidya S, Belinskaia D.A, Shestakova N.N, Kumar R, Singh S, Tiwari V*. Tozasertib Attenuates Neuropathic Pain by Interfering with Aurora Kinase and KIF11 Mediated Nociception. ACS Chemical Neuroscience 2021 Jun 2;12(11):1948-1960. (Impact Factor- 4.418) ISSN: 1948-7193. *CORRESPONDING AUTHOR
Vaidya S, Shantanu P. A, Tiwari V*. Attenuation of ongoing neuropathic pain by peripheral acting opioid involves activation of central dopaminergic neurocircuitry Neuroscience Letters. 2021 Feb 18;135751. (Impact Factor- 3.046) ISSN: 0304-3940. *CORRESPONDING AUTHOR
Uniyal A, Mahapatra MK, Tiwari V, Sandhir R, Kumar R. Targeting SARS-CoV-2 main protease: structure based virtual screening, in silico ADMET studies and molecular dynamics simulation for identification of potential inhibitors. J Biomol Struct Dyn. 2020 Nov 23:1-17. (Impact Factor- 3.310) ISSN: 7391102
Prakash S, Rai U, Uniyal A, Tiwari V*, Singh S*. Sitagliptin mitigates oxidative stress and up-regulates Mitochondrial Biogenesis markers in Brown adipose tissues of High-Fat Diet fed obese mice through AMPK phosphorylation. Obesity Medicine 2020. September 19: 100265 (Impact Factor- 1.50) ISSN: 2451-8476. *CORRESPONDING AUTHOR
Tiwari V, He SQ, Huang Q, Liang L, Yang F, Chen Z, Tiwari V, Fujita W, Devi LA, Dong X, Guan Y, Raja SN. Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents. Pain. 2020 Apr; 161(4):842-855. (Impact Factor- 6.961) ISSN: 0304-3959
Prakash S, Rai U, Kosuru R, Tiwari V*, Singh S*. Amelioration of diet-induced metabolic syndrome and fatty liver with Sitagliptin via regulation of adipose tissue inflammation and hepatic Adiponectin/AMPK levels in mice. Biochimie. 2020 Jan; 168:198-209. (Impact Factor- 4.079) ISSN: 0300-9084 *CORRESPONDING AUTHOR
Rai U, Kosuru R, Prakash S, Tiwari V*, Singh S*. Tetramethylpyrazine alleviates diabetic nephropathy through the activation of Akt signalling pathway in rats. Eur J Pharmacol. 2019 Dec 15; 865:172763. (Impact Factor- 4.432) ISSN: 0014-2999 *CORRESPONDING AUTHOR
Rai U, Kosuru R, Prakash S, Singh SP, Birla H, Tiwari V*, Singh S*. Tetramethylpyrazine prevents diabetes by activating PI3K/Akt/GLUT-4 signalling in animal model of type-2 diabetes. Life Sci. 2019 Nov 1; 236:116836. (Impact Factor- 5.037) ISSN: 0024-3205 *CORRESPONDING AUTHOR
Sharma P, Tripathi A, Tripathi PN, Prajapati SK, Seth A, Tripathi MK, Srivastava P, Tiwari V, Krishnamurthy S, Shrivastava SK. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. Eur J Med Chem. 2019 Apr 1; 167:510-524. (Impact Factor- 6.514) ISSN: 0223-5234
Sharma D, Gondaliya P, Tiwari V, Kalia K. Kaempferol attenuates diabetic nephropathy by inhibiting RhoA/Rho-kinase mediated inflammatory signaling. Biomedicine & Pharmacotherapy 2019 Jan; 109:1610-1619. (Impact Factor- 6.529) ISSN: 0753-3322
Tiwari V, Anderson M, Yang F, Tiwari V, Zheng Q, He SQ, Zhang T, Shu B, Chen X, Grenald SA, Stephens KE, Chen Z, Dong X, Raja SN, Guan Y. Peripherally Acting μ-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats. Anesthesiology. 2018 Jun;128(6):1220-1236. (Impact Factor- 7.892) ISSN: 0003-3022
He SQ, Xu Q, Tiwari V, Yang F, Anderson M, Chen Z, Grenald S, Raja SN, Dong X, Guan Y*. Oligomerization of MrgC11 and μ-opioid receptors in sensory neurons enhances morphine analgesia. Science Signaling 2018 Jun 19;11(535). pii: eaao3134 (Impact Factor- 8.192) ISSN: 1937-9145
Sharma K, Sharma D, Sharma M, Sharma N, Bidve P, Prajapati N, Kalia K, Tiwari V*. Astaxanthin ameliorates behavioral and biochemical alterations in in-vitro and in-vivo model of neuropathic pain. Neuroscience Letters 2018 May 1; 674:162-170. (Impact Factor- 3.046) ISSN: 0304-3940. *CORRESPONDING AUTHOR
Fernandes V, Sharma D, Kalia K, Tiwari V. Neuroprotective effects of silibinin: an in silico and in vitro study. Int J Neurosci 2018 Oct;128(10):935-945. (Impact Factor- 2.292) ISSN: 1543-5245. *CORRESPONDING AUTHOR
Li Z, Tseng PY, Tiwari V, Xu Q, He SQ, Wang Y, Zheng Q, Han L, Wu Z, Blobaum AL, Cui Y, Tiwari V, Sun S, Cheng Y, Huang-Lionnet JH, Geng Y, Xiao B, Peng J, Hopkins C, Raja SN, Guan Y*, Dong X*. Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1996-E2005. (Impact Factor- 11.205) ISSN: 1091-6490. FIRST CO-AUTHOR.
Fei Yang, Qian Xu, Bin Shu, Tiwari V, Shao-Qiu He, Tiwari V, Louis P. Vera-Portocarrero, Xinzhong Dong, Bengt Linderoth, Srinivasa N. Raja, Yun Wang, Yun Guan*. Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation. PAIN 2016 Nov;157(11):2582-2593. (Impact Factor- 6.961) ISSN: 0304-3959
Tiwari V, Yang F, He SQ, Shechter R, Zhang C, Shu B, Zhang T, Tiwari V, Wang Y, Dong X, Guan Y, Raja SN*. Activation of Peripheral Mu-Opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) amide Leads to Modality-preferred Inhibition of Neuropathic Pain. Anesthesiology 2016 Mar;124(3):706-20. (Impact Factor- 7.892) ISSN: 0003-3022
Cao J, Wang PK, Tiwari V, Liang L, Lutz BM, Shieh KR, Zang WD, Kaufman AG, Bekker A, Gao XQ, Tao YX*. Short-term pre- and post-operative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception. Molecular Pain. 2015 Dec 2;11(1):73. (Impact Factor- 3.395) ISSN: 1744-8069
Li Z, He SQ, Tseng PY, Xu Q, Tiwari V, Yang F, Shu B, Zhang T, Tang Z, Raja SN, Wang Y, Dong X, Guan Y*. The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms. Neuroscience. 2015 Aug 6; 300:393-403. (Impact Factor- 3.590) ISSN: 0306-4522
Pang Z, Sakamoto T, Tiwari V, Kim YS, Yang F, Dong X, Güler AD, Guan Y, Caterina MJ*. Selective keratinocyte stimulation is sufficient to evoke nociception in mice. PAIN 2015 Apr;156(4):656-65. (Impact Factor- 6.961) ISSN: 0304-3959
Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X*. Tmem100 is a regulator of TRPA1-TRPV1 complex and contributes to persistent pain. Neuron. 2015 Feb 18;85(4):833-46. (Impact Factor- 17.173) ISSN: 0896-6273
Sdrulla AD, Xu Q, He SQ, Tiwari V, Yang F, Zhang C, Shu B, Shechter R, Raja SN, Wang Y, Dong X, Guan Y*. Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice. Pain. 2015 Jun;156(6):1008-17. (Impact Factor- 6.961) ISSN: 1532-2149
Yang F, Zhang C, Xu Q, Tiwari V, He SQ, Wang Y, Dong X, Vera-Portocarrero LP, Wacnik PW, Raja SN, Guan Y*. Electrical stimulation of dorsal root entry zone attenuates wide-dynamic range neuronal activity in rats. Neuromodulation. 2015 Jan;18(1):33-40; discussion 40. (Impact Factor- 4.722) ISSN: 1525-1403
Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, Tang Z, Han L, Chu YX, Wang Y, Hin N, Tsukamoto T, Slusher B, Guan X, Wei F, Raja SN, Dong X, Guan Y*. Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice. Pain. 2014 Aug;155(8):1613-21. (Impact Factor- 6.961) ISSN: 0304-3959
Xu Q, Cheong YK, He SQ, Tiwari V, Liu J, Raja SN, Li J, Guan Y, Li W*. Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury. Neuroscience Letters 2014 Apr 30; 566:194-9. (Impact Factor- 3.046) ISSN: 0304-3940
Xu Q, Cheong YK, Yang F, Tiwari V, Li J, Liu J, Raja SN, Li W, Guan Y*. Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury. Neuroscience Letters. 2014 Mar 20; 563:45-50. (Impact Factor- 3.046) ISSN: 0304-3940
Fan L, Guan X, Wang W, Zhao JY, Zhang H, Tiwari V, Hoffman PN, Li M, Tao YX*. Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons. Molecular Pain. 2014 Jan 29;10(1):8. [Epub ahead of print] (Impact Factor- 3.395) ISSN: 1744-8069
Yang F, Xu Q, Cheong YK, Shechter R, Sdrulla A, He S, Tiwari V, Dong X, Wacnik PW, Meyer RA, Raja SN, Guan Y*. Comparison of intensity-dependent inhibition of spinal wide-dynamic range neurons by dorsal column and peripheral nerve stimulation in a rat model of neuropathic pain. European Journal of Pain. 2014 Aug;18(7):978-88. (Impact Factor- 3.931) ISSN: 1532-2149
Xu JT, Zhao JY, Zhao X, Ligons D, Tiwari V, Atianjoh FE, Lee CY, Liang L, Zang W, Njoku D, Raja SN, Yaster M, Tao YX*. Opioid receptor–triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia. The Journal of Clinical Investigation 2014 Feb 3;124(2):592-603. (Impact Factor- 14.808) ISSN: 0021-9738
He SQ, Han L, Li Z, Xu Q, Tiwari V, Yang F, Guan X, Wang Y, Raja SN, Dong X, Guan Y*. Temporal changes in MrgC expression after spinal nerve injury. Neuroscience. 2013 Dec 25;261C:43-51. [Epub ahead of print] (Impact Factor- 3.590) ISSN: 0306-4522.
He SQ, Li Z, Chu Y-X, Han L, Xu Q, Li M, Yang F, Liu Q, Tang Z, Wang Y, Hin N, Tsukamato T, Slusher B, Tiwari V, Shechter R, Wei F, Raja SN, Dong X, Guan Y*. MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain. Pain. 2014 Mar;155(3):534-44. (Impact Factor- 6.961) ISSN: 0304-3959.
Zhao X, Tang Z, Zhang H, Atianjoh F, Zhao J, Liang L, Wang W, Guan X, Kao S, Tiwari V, Gao Y, Hoffman P, Cui H, Li M, Dong X, Tao YX*. A long noncoding RNA contributes to neuropathic pain by silencing Kv1.2 in primary afferent neurons. Nature Neuroscience 2013 Aug;16(8):1024-31. (Impact Factor- 24.884) ISSN: 1097-6256
Tiwari V, Chopra K*. Protective effect of curcumin against chronic alcohol-induced cognitive deficits and neuroinflammation in the adult rat brain. Neuroscience. 2013 Aug 6; 244:147-58. (Impact Factor- 3.590) ISSN: 0306-4522
Tiwari V, Chopra K*. Resveratrol Abrogates Alcohol-induced Cognitive Deficits by Attenuating Oxidative-Nitrosative Stress and Inflammatory Cascade in the Adult Rat Brain. Neurochemistry International 2013 May;62(6):861-9 (Impact Factor- 3.921) ISSN: 0197-0186
Tiwari V, Chopra K*. Attenuation of oxidative stress, neuroinflammation, and apoptosis by curcumin prevents cognitive deficits in rats postnatally exposed to ethanol. Psychopharmacology (Berl). 2012 Dec;224(4):519-35 (Impact Factor- 4.530) ISSN: 0033-3158
Tiwari V, Arora V, Chopra K*. Attenuation of NF-κβ Mediated Apoptotic Signaling by Tocotrienol Ameliorates Cognitive Deficits in Rats Postnatally Exposed to Ethanol. Neurochemistry International 2012 Aug;61(3):310-20 (Impact Factor- 3.921) ISSN: 0197-0186
Tiwari V, Kuhad A, Chopra K*. Neuroprotective Effect of Vitamin E Isoforms Against Chronic Alcohol-induced Peripheral Neurotoxicity: Possible Involvement of Oxidative-Nitrodative Stress. Phytotherapy Research 2012 Nov;26(11):1738-45 (Impact Factor- 5.878) ISSN: 1099-1573
Arora V, Kuhad A, Tiwari V, Chopra K*. Curcumin Ameliorates Reserpine-induced Pain Depression Dyad: Behavioral, Biochemical, Neurochemical and Molecular Evidences. Psychoneuroendocrinology 2011. Nov;36(10):1570-81 (Impact Factor- 4.905) ISSN: 0306-4530
Misra S, Tiwari V, Kuhad A, Chopra K*. Modulation of nitrergic pathway by sesamol prevents cognitive deficits and associated biochemical alterations in intracerebroventricular streptozotocin administered rats. European Journal of Pharmacology. 2011 Jun 1;659(2-3):177-86. (Impact Factor- 4.432) ISSN: 0014-2999
Tiwari V, Chopra K*. Resveratrol Prevents Alcohol-induced Cognitive Deficits and Brain Damage by blocking Inflammatory Signaling and Cell Death Cascade in Neonatal Rat Brain. Journal of Neurochemistry 2011 May;117(4):678-90. (Impact Factor- 5.372) ISSN: 1471-4159
Tiwari V, Kuhad A, Chopra K*. Emblica Officinalis Corrects Functional, Biochemical and Molecular Deficits in Experimental Diabetic Neuropathy by Targeting the Oxido-nitrosative Stress Mediated Inflammatory Cascade. Phytotherapy Research 2011 Oct;25(10):1527-36 (Impact Factor- 5.878) ISSN: 1099-1573
Tiwari V, Kuhad A, Chopra K*. Amelioration of functional, biochemical and molecular deficits by epigallocatechin gallate in experimental model of alcoholic neuropathy. European Journal of Pain. 2011 Mar;15(3):286-92. (Impact Factor- 3.931) ISSN: 1090-3801
Tiwari V, Kuhad A, Chopra K*. Epigallocatechin-3-gallate Ameliorates Alcohol-Induced Cognitive Dysfunctions and Apoptotic Neurodegeneration in the Developing Rat Brain. International Journal of Neuropsychopharmacology 2010 Sep;13(8):1053-66. (Impact Factor- 5.176) ISSN: 1461-1457)
Chopra K*, Tiwari V, Arora V, Kuhad A. Sesamol Suppresses Neuro-Inflammatory Cascade in Experimental Model of Diabetic Neuropathy. The Journal of Pain. 2010 Oct;11(10):950-7 (Impact Factor-4.820) ISSN: 1526-5900
Sachdeva AK, Kuhad A, Tiwari V, Arora V, Chopra K*. Protective effect of epigallocatechin gallate in murine water-immersion stress model of chronic fatigue syndrome. Basic & Clinical Pharmacology & Toxicology 2010 Jun; 106(6):490-6 (Impact Factor-4.080) ISSN: 1742-7843
Sachdeva AK, Kuhad A, Tiwari V, Chopra K*. Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and biochemical evidence. Behavioural Brain Research. 2009 Dec 28;205(2):414-20 (Impact Factor-3.332) ISSN: 0166-4328
Tiwari V, Kuhad A, Chopra K*. Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy. Pain. 2009 Sep;145(1-2):129-35 (Impact Factor- 6.961) ISSN: 0304-3959
Tiwari V, Kuhad A, Chopra K*. Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats. Behavioural Brain Research 2009 Nov 5;203(2):296-303 (Impact Factor-3.332) ISSN: 0166-4328
Tiwari V, Kuhad A, Bishnoi M, Chopra K*. Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats. Pharmacology Biochemistry and Behavior 2009 Aug;93(2):183-9 (Impact Factor-3.533) ISSN: 0091-3057
Kuhad A, Bishnoi M, Tiwari V, Chopra K*. Suppression of NF-κβ signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits. Pharmacology Biochemistry and Behavior 2009; 92(2):251-9) (Impact Factor-3.533) ISSN: 0091-3057
REVIEW ARTICLES: Peer Reviewed
Uniyal, A., Tiwari, V., Tsukamoto, T., Dong, X., Guan, Y. and Raja, S.N., 2023. Targeting sensory neuron GPCRs for peripheral neuropathic pain. Trends in Pharmacological Sciences. (Impact Factor – 17.63)
Nigam, M., Mishra, A.P., Deb, V.K., Dimri, D.B., Tiwari, V., Bungau, S.G., Bungau, A.F. and Radu, A.F., 2023. Evaluation of the association of chronic inflammation and cancer: Insights and implications. Biomedicine & Pharmacotherapy, 164, p.115015 (Impact Factor- 7.419)
Modi A, Pandey P, Akhilesh, Uniyal A, Chouhan D, Agrawal S, Allani M, Singh AK, Kumar S, Tiwari V*. Disentangling the enigmatic role of ephrin signaling in chronic pain: Moving towards future anti-pain therapeutics. Life Sciences. 2022 In-press (Impact Factor- 6.780) ISSN: 0024-3205. *CORRESPONDING AUTHOR
Naren, P, Cholkar, A, Kamble, S, Samim, K.S., Srivastava, S, Madan, Mehra, N, Tiwari, V, Singh, S.B. and Khatri, D.K. Pathological and Therapeutic Advances in Parkinson’s Disease: Mitochondria in the Interplay. Journal of Alzheimer's Disease, (Preprint), pp.1-30. 2022. (Impact factor: 9.423). ISSN: 1939-0041.
Shah, S, Famta, P, Tiwari, V, Kotha, A.K, Kashikar, R, Chougule, M.B, Chung, Y.., Steinmetz, N.F, Uddin, M, Singh, S.B. and Srivastava, S. Instigation of the epoch of nanovaccines in cancer immunotherapy. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, pp1870. 2022. (Impact factor: 9.423). ISSN: 1939-0041.
Roy T, Uniyal A, Akhilesh, Tiwari V*. Multifactorial Pathways in Burn Injury-induced Chronic Pain: Novel Targets and their Pharmacological Modulation. Molecular biology reports. 2022. (Impact factor: 2.6). ISSN: 0024-3205. *CORRESPONDING AUTHOR
2. Rani M, Uniyal A, Akhilesh, Tiwari V*. Decrypting the Cellular and Molecular Intricacies Associated with COVID-19-induced Chronic Pain. Metabolic brain disease. 2022. (Impact Factor- 3.584) ISSN: 1573-7365. *CORRESPONDING AUTHOR
3. Akhilesh, Uniyal A, Gadepalli A, Tiwari V, Allani M, Chouhan D, Ummadisetty O, Verma N, Tiwari V*. Unlocking the potential of TRPV1 based siRNA therapeutics for the treatment of chemotherapy-induced neuropathic pain. Life Sciences. 2022 Jan 1; 288:120187. (Impact Factor- 5.037) ISSN: 0024-3205. *CORRESPONDING AUTHOR
4. Naik GG, Uniyal A, Chouhan D, Tiwari V, Sahu AN. Natural Products and some semi- synthetic analogues as potential TRPV1 Ligands for attenuating Neuropathic pain. Current pharmaceutical biotechnology 2022. (Impact Factor- 2.6) ISSN: 1873-4316.
5. Gadepalli A, Akhilesh, Uniyal A, Modi A, Chouhan D, Ummadisetty O, Khanna S, Solanki S, Allani M, Tiwari V*. Multifarious Targets and Recent Developments in the Therapeutics for the Management of Bone Cancer Pain. ACS chemical neuroscience. 2021 Nov 1;12(22):4195-208. ACS Chem Neurosci. 2021 Aug 18;12(16):2956-2963. (Impact Factor- 4.418) ISSN: 1948-7193 *CORRESPONDING AUTHOR
6. Uniyal A, Tiwari V, Rani M, Tiwari V*. Immune-microbiome interplay and its implications in neurodegenerative disorders. Metabolic Brain Disease. 2021 Aug 6:1-21. (Impact Factor- 3.584) ISSN: 1573-7365. *CORRESPONDING AUTHOR
7. Uniyal A, Thakur V, Rani M, Tiwari V, Akhilesh, Gadepalli A, Ummadisetty O, Modi A, Tiwari V*. Kinesin Nanomotors Mediated Trafficking of NMDA-Loaded Cargo as A Novel Target in Chronic Pain. ACS Chem Neurosci. 2021 Aug 18;12(16):2956-2963. (Impact Factor- 4.418) ISSN: 1948-7193 *CORRESPONDING AUTHOR
8. Singh RS, Singh A, Kaur H, Batra G, Sarma P, Kaur H, Bhattacharyya A, Sharma AR, Kumar S, Upadhyay S, Tiwari V, Avti P, Prakash A, Medhi B. Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review. Phytother Res 2021 Jun 16. doi: 10.1002/ptr.7150. (Impact Factor- 4.087) ISSN: 1099-1573.
9. Thakur V, Uniyal A, Tiwari V*. A comprehensive review on pharmacology of efflux pumps and their inhibitors in antibiotic resistance. Eur J Pharmacol. 2021 May 5; 903:174151. (Impact Factor- 4.432) ISSN: 0014-2999 *CORRESPONDING AUTHOR
10. Tiwari V, Venugopala KN, Deb PK. Perspectives of In silico, In vitro and Integrated ADMET Profiling in the Drug Discovery and Development. Current Drug Metabolism 2021. (Impact Factor – 3.731)
11. Borah P, Deb PK, Venugopala KN, Al-Shar'i NA, Singh V, Deka S, Srivastava A, Tiwari V, Mailavaram RP. Tuberculosis: An Update on Pathophysiology, Molecular Mechanisms of Drug Resistance,Newer Anti-TB Drugs, Treatment Regimens and Host-Directed Therapies. Current Topics in Medicinal Chemistry 2021;21(6):547-570. (Impact Factor- 3.295) ISSN: 1873-4294
12. Dagamajalu S, Rex DAB, Gopalakrishnan L, Karthikkeyan G, Gurtoo S, Modi PK, Mohanty V, Mujeeburahiman M, Soman S, Raju R, Tiwari V, Prasad TSK. A network map of endothelin mediated signaling pathway. Journal of Cell Communication and Signaling 2021 Jun;15(2):277-282. (Impact Factor- 5.782) ISSN: 1873-9601
13. Shaw S, Uniyal A, Gadepalli A, Tiwari V, Belinskaia DA, Shestakova NN, Venugopala KN, Deb PK, Tiwari V*. Adenosine receptor signalling: Probing the potential pathways for the ministration of neuropathic pain. European Journal of Pharmacology, 2020 Oct 2;889:173619. (Impact Factor- 4.432) ISSN: 0014-2999 *CORRESPONDING AUTHOR
14. Chouhan D, Uniyal A, Gadepalli A, - A, Tiwari V, Agrawal S, Roy TK, Shaw S, Purohit N, Tiwari V*. Probing the Manipulated Neurochemical Drive in Alcohol Addiction and Novel Therapeutic Advancements. ACS Chem Neurosci. 2020, May 6;11(9):1210-1217. (Impact Factor- 4.418) ISSN: 1948-7193 *CORRESPONDING AUTHOR
15. Uniyal A, Gadepalli A, Akhilesh, Tiwari V*. Underpinning the Neurobiological Intricacies Associated with Opioid Tolerance. ACS Chem Neurosci. 2020, Mar 18;11(6):830-839. (Impact Factor- 4.418) ISSN: 1948-7193 *CORRESPONDING AUTHOR
16. Bidve P, Prajapati N, Kalia K, Tekade R, Tiwari V*. Emerging Role of Nanomedicine in the Treatment of Neuropathic Pain. J Drug Target. 2020 Jan;28(1):11-22. (Impact Factor- 3.121). ISSN: 1029-2330 *CORRESPONDING AUTHOR
17. P.A S, Sharma D, Sharma M, Vaidya S, Sharma K, Kalia K, Tao YX, Shard A, Tiwari V*. Kinesins: Motor Proteins as Novel Target for the Treatment of Chronic Pain. Molecular Neurobiology 2019 Jun;56(6):3854-3864. (Impact Factor- 5.590). ISSN: 1559-1182 *CORRESPONDING AUTHOR
18. Sharma D, Verma S, Vaidya S, Kalia K, Tiwari V*. Recent Updates on GLP-1 Agonists: Current Advancements & Challenges. Biomedicine & Pharmacotherapy 2018 Dec; 108:952-962 (Impact Factor- 6.529). ISSN: 1950-6007*CORRESPONDING AUTHOR
19. Fernandes V, Sharma D, Vaidya S, P A S, Guan Y, Kalia K, Tiwari V* Cellular and molecular mechanisms driving neuropathic pain: recent advancements and challenges. Expert Opinion on Therapeutic Targets 2018 Feb;22(2):131-142. (Impact Factor- 6.902). ISSN: 1744-7631*CORRESPONDING AUTHOR
20. Patel S, Sharma D, Kalia K, Tiwari V*. Crosstalk between Endoplasmic Reticulum Stress and Oxidative Stress in Schizophrenia: The Dawn of New Therapeutic Approaches. Neuroscience and Biobehavioral Reviews 2017 Dec; 83:589-603. (Impact Factor- 8.989). ISSN: 0149-7634*CORRESPONDING AUTHOR
21. Sharma D, Bhattacharya P, Kalia K*, Tiwari V*. Diabetic Nephropathy: New Insights into Established Therapeutic Paradigms and Novel Molecular Targets. Diabetes Research and Clinical Practice 2017 Jun; 128:91-108. (Impact Factor- 5.602) ISSN: 168-8227. *CORRESPONDING AUTHOR
22. Tiwari V, Tiwari V, He SQ, Zhang T, Raja SN, Dong X, Guan Y*. Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy. Advances in Experimental Medicine and Biology 2016; 904:87-103. (co-first author) (Impact Factor- 2.622) ISSN: 0065-2598.
23. Tiwari V*, Guan Y and Raja SN*. Modulating the Delicate Glial-Neuronal Interactions in Neuropathic Pain: Promises and Potential Caveats. Neuroscience & Biobehavioral Reviews 2014 Sep;45C:19-27. (Impact Factor- 10.284). ISSN: 0149-7634.*CORRESPONDING AUTHOR
24. Chopra K*, Tiwari V. Alcoholic Neuropathy: Possible Mechanisms and Future Treatment Possibilities. British Journal of Clinical Pharmacology 2012 Mar;73(3):348-62 (Impact Factor- 4.335) ISSN: 1365-2125.
25. Chopra K*, Tiwari V. Fetal Alcohol Spectrum Disorders: An Overview of Diverse Mechanisms Involved. Pharmacos 2010; 37:37-43. Chopra K*, Kuhad A, Tiwari V. Rheumatoid Arthritis: A Pathobiological Perspective. Pharmacos 2009; 36:26-31