CODE-M

Our kit utilizes molecular tools to detect the presence of Mycobacterium tuberculosis (MTB) in a given sample and check for drug resistance. We combined minimalistic features of LAMP amplification to amplify the target DNA using MTB-specific sequences, then use them to search for mutations by targeting SNPs in katG and rpoB genes using Cas14a1 and sgRNA complex and detecting fluorescence emission upon cleavage of FQ pair.