The CMT Lab at IISER Berhampur is committed to unraveling the molecular and metabolic underpinnings of cancer metastasis to drive innovative therapeutic strategies. Our research spans the full spectrum of cancer biology, with a core emphasis on metastatic progression, metabolic reprogramming, the role of dietary habits in shaping the tumor microenvironment, and rational drug discovery.
Metastasis remains the leading cause of cancer-related mortality, yet its mechanistic basis is only partially understood. At CMT, we strive to bridge this knowledge gap by integrating cutting-edge approaches from cell biology, molecular oncology, epigenetics, and systems biology. We focus particularly on how obesity, diabetes, and other metabolic syndromes leave a lasting "memory" in tumor cells and drives metastasis.
Our lab explores how organelles like mitochondria, endoplasmic reticulum, and ribosomes regulate cellular stress responses and metastatic competence. Using a combination of cell lines, animal models, multi-omics platforms (metabolomics, transcriptomics, proteomics, epigenomics), and drug discovery pipelines, we seek to decode complex interactions within the tumor microenvironment.
Our long-term vision is to contribute to next-generation, non-invasive diagnostics and targeted therapeutics that are accessible, affordable, and culturally sensitive especially for underserved populations.
Join us as we advance the frontier of cancer research with curiosity, compassion, and a commitment to real-world impact.