Dr. Charles Moen Rice III (born 1952)

Charles Moen Rice (born August 25, 1952) is an American virologist and Nobel Prize laureate whose main area of research is the Hepatitis C virus. He is a professor of virology at the Rockefeller University in New York City and an adjunct professor at Cornell University and Washington University School of Medicine. At the time of the award he was a faculty at Rockefeller.

Rice is a Fellow of the American Association for the Advancement of Science, member of the National Academy of Sciences and was president of the American Society for Virology from 2002 to 2003. He received the 2016 Lasker-DeBakey Clinical Medical Research Award, jointly with Ralf F. W. Bartenschlager and Michael J. Sofia.[1][2] Along with Michael Houghton and Harvey J. Alter, he was awarded the 2020 Nobel Prize in Physiology or Medicine "for the discovery of Hepatitis C virus."[3][4]

Early life and education

Charles Moen Rice was born on August 25, 1952, in Sacramento, California.[5][6]

Rice graduated Phi Beta Kappa [7] with a BS in zoology from University of California, Davis, in 1974. In 1981, he received his PhD in biochemistry from the California Institute of Technology, where he studied RNA viruses in the laboratory of James Strauss.[8] He remained at Caltech for four years to do postdoctoral research.[9][10]

Career

After his postdoctoral work, Rice moved with his research group to the Washington University School of Medicine in 1986, where he remained until 2001.[3]

Rice has been the Maurice R. and Corinne P. Greenberg Professor at Rockefeller University since 2001. He is also an adjunct professor at Washington University School of Medicine and Cornell University. He has served on committees for the Food and Drug Administration, National Institutes of Health, and World Health Organization.[9]

He was the editor of Journal of Experimental Medicine from 2003 to 2007, Journal of Virology from 2003 to 2008, and PLoS Pathogens from 2005 to present. He has been an author of over 400 peer-reviewed publications.[9]

Research

Nobel Prize in Physiology or Medicine 2020: Seminal experiments by HJ Alter, M Houghton and CM Rice leading to the discovery of HCV as the causative agent of non-A, non-B hepatitis.

While at Caltech, he was involved in researching the genome of Sindbis virus and the establishment of flaviviruses as their own family of viruses. The strain of yellow fever virus he used for this work was eventually used for the development of the yellow fever vaccine. While exploring Sindbis virus at Washington University in St. Louis, Rice described how he produced infectious flavivirus RNA in the laboratory in a 1989 paper published in The New Biologist. The paper attracted the attention of Stephen Feinstone who was studying hepatitis C virus and suggested that Rice use the technique to develop a vaccine for hepatitis C. In 1997, Rice cultured the first infectious clone of hepatitis C virus for use in studies on chimpanzees in whom the virus was also endemic. In 2005, Rice was also part of a team that showed that a strain of an acute form of the virus identified in a human patient can be forced to replicate in a laboratory setting. Rice's contribution to hepatitis C research has earned him many awards.[6]

Awards

1986 Pew Charitable Trust scholarship[11]
2004 Elected fellow, American Association for the Advancement of Science [12]
2005 Elected member, National Academy of Sciences [13]
2005 Elected fellow, American Academy of Microbiology [14]
2007 M.W. Beijerinck Virology Prize [15]
2015 Robert Koch Prize [16]
2016 Artois-Baillet Latour Health Prize [17]
2016 Lasker Award [10]
2020 Nobel Prize in Physiology or Medicine [3]

References

^ "The Rockefeller University » Scientists & Research". rockefeller.edu. Retrieved November 16, 2016.
^ "2016 Lasker~DeBakey Clinical Medical Research Award: Hepatitis C replicon system and drug development". The Lasker Foundation. 2016. Retrieved November 18, 2016.
a b c "Press release: The Nobel Prize in Physiology or Medicine 2020". Nobel Foundation. Retrieved October 5, 2020.
^ Wu, Katherine J.; Victor, Daniel (October 6, 2020). "Nobel Prize in Medicine Awarded to Scientists Who Discovered Hepatitis C Virus". The New York Times. ISSN 0362-4331. Retrieved October 7, 2020.
^ Freund, Alexander (October 5, 2020). "Nobelpreis für Medizin geht an Hepatitis-C-Entdecker". Deutsche Welle. Retrieved October 5, 2020.
a b Nair, P. (April 18, 2011). "Profile of Charles M. Rice". Proceedings of the National Academy of Sciences. 108 (21): 8541–8543. Bibcode:2011PNAS..108.8541N. doi:10.1073/pnas.1105050108. PMC 3102406. PMID 21502493.
^ @PhiBetaKappa [Phi Beta Kappa] (October 5, 2020). "Congratulations to #PBKmember Charles M. Rice on being awarded the 2020 #NobelPrize in Physiology or Medicine! Dr. Rice was inducted at @ucdavis in 1974. #PBKPride". Twitter. Retrieved October 6, 2020.
^ Rice, Charles Moen, III (1981). Studies on the Structural Proteins of Sindbis Virus (Ph.D. thesis). California Institute of Technology. OCLC 437056699. ProQuest 303097358.
a b c Rice, Charles M. (January 31, 2016). "Curriculum Vitae: Charles M. Rice" (PDF). Fonds Baillet Latour. Archived from the original (PDF) on February 14, 2019. Retrieved October 6, 2020.
a b "Charles M. Rice wins Lasker Award for groundbreaking work on the hepatitis C virus". The Rockefeller University. September 13, 2016. Retrieved April 20, 2018.
^ "Charles M. Rice, Ph.D." Pew Trusts. Retrieved October 6, 2020.
^ "Elected Fellows". AAAS.org. Retrieved October 6, 2020.
^ "Charles Rice". National Academy of Sciences.
^ "Nobel Prize Awarded to Power Trio of ASM Contributors". ASM.org. October 5, 2020. Retrieved October 6, 2020.
^ "CHARLES RICE". KNAW. Retrieved October 6, 2020.
^ "Robert-Koch-Preis". Robert Koch Stiftung. Retrieved October 6, 2020.
^ "THE BAILLET LATOUR HEALTH PRIZE - 2018 HISTORICAL BACKGROUND" (PDF). FRNS. Retrieved December 11, 2017.

Born: August 25, 1952 (age 70)Sacramento California

Awards And Honors: Nobel Prize (2020)

Subjects Of Study: hepatitis C virus Sindbis virus

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Charles M. Rice, in full Charles Moen Rice III,

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Name : Charles Moen Rice III / [Charles M Rice III]
Birth Date : Aug 1952
Residence Date : 2015-2020
Address : 12 Rockledge Ln 16 / New Milford, Connecticut, USA / 06776
Second Residence Date : 1998-2020
Second Address : 1230 York Ave / New York, New York, USA / 10065
Third Residence Date : 1998-2017
Third Address : 1161 York Ave Apt 12f / New York, New York, USA / 10065
Fourth Residence Date : 2011
Fourth Address : 3909 Berrendo Dr / Sacramento, California, USA / 95864

2016 (May 31) - TWIV show

Hosted by : Dr. Vincent Raimondi Racaniello (born 1953)

Included : Dr. Laura Dean Kramer (born 1946) / Dr. Michael S. Diamond (born 1964) / Dr. Charles Moen Rice III (born 1952) /

May 31, 2016 - TWIV (This Week in Virology): ZIKA VIRUS LIVE STREAMBitchute / Odysee / Rumble

2020 (Oct 05) - UCDavis.edu : "Alumnus Charles Rice Wins Nobel Prize for Medicine"

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Charles M. Rice, who earned his undergraduate degree from the University of California, Davis, is a recipient of the 2020 Nobel Prize in physiology or medicine announced this morning (Oct. 5).

“I’m delighted to see the work of one of our alumni honored with a Nobel Prize,” UC Davis Chancellor Gary S. May said. “On behalf of the entire UC Davis family, I offer my heartfelt congratulations to Professor Rice. His research and dedication inspire us. This is who we are.”

Rice, who is the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University in New York, shares the prize with Harvey J. Alter, National Institutes of Health, and Michael Houghton of the University of Alberta, Canada, for the discovery of the hepatitis C virus.

“In the midst of the current pandemic, Professor Rice’s work reminds us of how challenging viral diseases are to eradicate and how revealing basic biological mechanisms of disease is critical to designing treatments,” said Mark Winey, dean of the UC Davis College of Biological Sciences. “The college is so proud to have contributed to the education of this scientist.”

Majored in zoology

Rice graduated from UC Davis in 1974 with a bachelor’s degree in zoology. Originally part of the College of Letters and Science, the zoology program became part of the Division — now the College — of Biological Sciences when it was formed in 1970. He went on to earn his doctorate from the California Institute of Technology.

Globally, some 71 million people are living with hepatitis C infection, according to an estimate by the World Health Organization. The virus causes liver inflammation and cirrhosis and is the leading cause of liver cancer in the United States.

Hepatitis C virus is transmitted through blood and other body fluids. Prior to its identification, hepatitis C was contracted by people receiving contaminated blood transfusion, organ transplants, or other blood products such as clotting factors used to treat hemophilia, said Christopher Bowlus, chief of gastroenterology and hepatology, UC Davis Department of Internal Medicine. The identification of the virus by Rice, Alter, Houghton and their colleagues enabled rapid testing for the virus in donated blood, removing the risk of transmission.

1st to culture hepatitis C virus

Rice was the first scientist to succeed in culturing hepatitis C virus, said James Letts, assistant professor of molecular and cellular biology at UC Davis. Being able to grow the virus in a laboratory has enabled research leading to medicines that can cure the disease, potentially saving millions of lives.

Letts worked in Rice’s laboratory for three months as a graduate student at The Rockefeller University before moving to another laboratory where he completed his Ph.D. “He’s a great scientist and mentor,” Letts said.

Rice visited UC Davis in 2014 to give a Tracy and Ruth Storer Lecture in Life Sciences for the College of Biological Sciences.

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Name:

Charles M Rice Rd

[Charles Rice Rd]

Birth Date:

25 Aug 1952

Phone Number:

531-8702

Address:

4304 Maryland Ave

Residence:

Saint Louis, MO

Postal Code:

63108-2704

Second Phone Number:

531-8702

Second Address:

4304 Maryland Ave

Second Residence:

Saint Louis, MO

Second Postal Code:

63108-2704

Third Residence Date:

1986

Third Phone Number:

531-8702

Third Address:

660 S Euclid Ave # 8093

Third Residence:

Saint Louis, MO

Third Postal Code:

63110-1010

Fourth Residence Date:

1986

Fourth Phone Number:

531-8702

Fourth Address:

660 S Euclid Ave # 8093

Fourth Residence:

Saint Louis, MO

Fourth Postal Code:

63110-1010