Mandatory Course Key Areas / Depth of Knowledge Required
Mandatory Course Key Areas / Depth of Knowledge Required
Structure of DNA
Nucleotides (deoxyribose sugar, phosphate and base), sugar–phosphate backbone, base pairing (adenine - thymine and guanine - cytosine), by hydrogen bonds and double stranded antiparallel structure, with deoxyribose and phosphate at 3' and 5' ends of each strand respectively, forming a double helix.
The base sequence of DNA forms the genetic code.
Organisation of DNA
Prokaryotes have a single, circular chromosome and smaller circular plasmids.
Eukaryotes all have linear chromosomes, in the nucleus, which are tightly coiled and packaged with associated proteins.
The associated proteins are called histones.
They also contain circular chromosomes in their mitochondria and chloroplasts.
Yeast is a special example of a eukaryote as it also has plasmids.