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14. Young-Pil Kim, Jeong Min Lee, Duc Loc Sai, Eun Song Lee. "Method for rapid selection of DNA aptamers using gold nanoparticle-facilitated assembly of supernatant transfer". (환경부 50%, BRL 50%)
; PCT Patent Application No. PCT/KR2024/016809 (Oct 30, 2024).
13. Young-Pil Kim, Jeonju Lee, Kyung-Min Kim. "Method for cyclic protein and uses thereof". (중견고리형 100%)
; PCT Patent Application No. PCT/KR2023/018396 (Nov 15, 2023).
12. Young-Pil Kim, Eun Song Lee, Tae-Wuk Kim. "Method for screening target-specific aptamers based on gold nanoparticle-assisted SELEX". (INST 중점 50%, 기초융 중점 50%)
; PCT Patent Application No. PCT/KR2020/010534 (Aug 10, 2020).
11. Young-Pil Kim, Eun Hye Kim. "A Composition for cancer cell death and its use" (중견발광 100%)
; PCT Patent Application No. PCT/KR2019/013900 (Oct 22, 2019).
; PCT Publication No. WO 2019/013900 (Apr 30, 2020).
10. Young-Pil Kim, Eun Song Lee, Miso Kim, Chang-Hwan Park, Eun-Hye Lee, Jin Saem Lee. "Astrocyte-specific nucleic acid aptamer and use thereof" (바이오의료기술사업 100%).
; PCT Patent No. PCT/KR2019/013539 (Oct 15, 2019)
; PCT Publication No. WO 2020/080809 (Apr 23, 2020)
; US Patent No. US 12,221,611 B2 (Feb 11, 2025)
9. Young-Pil Kim, Vinayakumar Gedi, Jin Oh Lee, Eun Hye Kim. "Mutant Gaussia Luciferase with Enhanced Bioluminescence Intensity". (중견연구 100%)
; PCT Patent Application No. PCT/KR2018/003023 (Mar 15, 2018)
; PCT Publication No. WO 2018/169317 A1 (Sep 20, 2018)
8. Young-Pil Kim, Myung Chan Gye, Eunsong Lee, Gye Baik Kim. "Methods for detecting endocrine disruptors using dual modes of colorimetric and fluorometric analysis". (환경호르몬 100%)
; US Patent Application No. US 15/884,868 (Jan 31, 2018)
; US Publication No. US 2018/0217062 A1 (Aug 02 2018)
; US Patent No. US 10,801,960 B2 (Oct 13, 2020)
7. Young-Pil Kim, Jin-Won Lee, Jin Oh Lee, Yoon-Mo Yang, Tae-Wuk Kim. "Composition for detection of biothiols comprising redox-regulating proteins". (삼성미래기술육성사업 100%)
; PCT Patent Application No. PCT/KR2017/012344 (Nov 02, 2017)
; US Patent Application No. US 16/347,321 (May 3, 2019)
; China Patent (CN) Application No. 201780082078.4 (Jul 3, 2019)
; CN Publication No. CN 110168367 A (Aug 23, 2019)
6. Jin-Won Lee, Myung Chan Gye, Su-Hyun Ryu, Young-Pil Kim. "Genetically modified bacterial strain for the detection of estrogenic compounds, and detection method for estrogenic compounds using the strain". (환경호르몬 100%)
; PCT Patent Application No. PCT/KR2017/001713 (Feb 16, 2017)
; US Patent Application No. US 16/146,677 (Sep 28, 2018)
5. Young-Pil Kim, Jin Oh Lee, Gae Baik Kim, Butaek Lim. "Phosphatase or Kinase Activity Detection Composition and Detection Method". (중견핵심 50%+나노원천 50%)
; PCT Patent Application No. PCT/KR2015/013849 (Dec 17, 2015)
; PCT Publication No. WO 2016099167 (Jun 23, 2016)
; US Patent Application No. US 15/624,018 (Jun 15, 2017)
; US Publication No. US 2017/0350881 A1 (Dec 7, 2017)
; US Patent No. US 10,718,761 B2 (Jul 21, 2020)
4. Hong Suk Kim, Myoung Jong Kwon, SeungJin Oh, Yungho Gwak, Young-Pil Kim, Ji-In Park, and EonSeon Jin. "Antifreeze Member".
; European Patent (EP) Application No. EP 15153358.5 (Jan 30, 2015)
; EP Publication No. EP 2921539 A1 (Sep 23, 2015)
; EP Patent No. EP 2921539 B1 (May 24, 2017)
; US Patent Application No. 14/657,443 (Mar 13, 2015)
; US Publication No. US 20150267100 A1 (Sep 24, 2015)
; US Patent No. US 9816021 B2 (Nov. 14, 2017)
3. Young-Pil Kim and Tae Geol Lee. "Bio-chip for Secondary Ion Mass Spectroscopy and Method of Fabricating the Same".
; US Patent No. US 8742336 B2 (Jun 03, 2014)
2. Hak-Sung Kim, Young-Pil Kim, Eunkeu Oh, Mi-Young Hong, Dohoon Lee, Tae Geol Lee, Dae Won Moon. "Construction of gold nanoparticle-based peptide chip, and assaying enzyme activity and inhibitor effect using secondary ion mass spectrometric analysis thereof".
; US Patent No. US 07951572 (May 31, 2011)
1. Jong Man Park, Hyung Joo Kim, Hee Jin Yang, Moon Sik Hyun, Young-Pil Kim, Tae Woo Cho. "Composite electrode for electrochemical COD measurement".
; WIPO(PCT) Patent No. WO 04/025672 (3/25, 2004)
; AU(Australia) Patent No. AU 2003261001 (4/30, 2004)
Domestic Patent (Application)
12. Kyung-Min Kim, Young-Pil Kim, Jeonju Lee, Chae Yeon Kim. 아연집게단백질 매개 금나노입자 비색법 및 이를 이용한 표적분자 검출 (Method for zinc finger protein-mediated gold nanoparticle colorimetry and its application to target molecule detection). (우선권 주장 가출원, 10-2024-0064016 (May 16, 2024). KR Patent Application (출원) 10-2025-0063834 (May 16, 2025).(한독과제 40%; BRL 40%; 환경부 20%)
11. Young-Pil Kim, Jeong Min Lee, Duc Loc Sai, Eun Song Lee. 금나노입자 연속첨가 및 응집을 이용한 초고속 DNA 압타머 선별법 (Method for rapid selection of DNA aptamers using gold nanoparticle-facilitated assembly of supernatant transfer). (우선권 주장 가출원, 10-2022-0152335, Oct 31, 2023) KR Patent Application (출원) 10-2024-0150905 (Oct 30, 2024). (환경부 50%, BRL 50%)
10. Young-Pil Kim, Jeonju Lee, Kyung-Min Kim. 고리형 단백질의 제조방법 및 이의 응용 (Method for cyclic protein and uses thereof). (우선권 주장 가출원, 10-2022-0152335, Nov 15, 2022) KR Patent Application (출원) 10-2023-0158140 (Nov 15, 2023). (중견고리형 100%)
9. Joonseok Lee, Dong Yun Lee, Young-Pil Kim, Dongkyu Kang, Hyung Shik Kim. 긴-수명을 가지는 근적외선 이미징 및 물 분자를 국소적으로 가열하기 위한 다기능성 입자 (Local water heating and near-Infrared long-ligetime imaging nanoparticles). KR Patent Application (출원) 10-2023-0061567 (May 12, 2023).
8. Young-Pil Kim, Joonseok Lee, Soo Hyun Han, Sung Hyeon Park. Sang Woo Park. 암표적 광역학치료용 단백질-상향변환 나노입자 복합체 및 이의 제조 방법 (Protein-upconversion nanoparticle complex for cancer-targeted photodynamic therapy and preparation method thereof). (우선권 주장 가출원, No. 10-2022-0057861, May 11, 2022) KR Patent Application (출원) 10-2023-0059637 (May 09, 2023). (중견고리형 40%, 바이오의료 40%, BRL 20%)
7. Young-Pil Kim, Hea Jin Kim, Jeong Min Lee, Hyo Il Jung, Kyung Yeon Lee. 디에틸헥실프탈레이트 검출용 압타머 및 이를 이용한 검출용 키트 (Aptamer for detection of diethylhexyl phthalate and kit for detecting using thereof). (우선권 주장 가출원, No. 10-2021-0146410, Oct 29, 2021) KR Patent Application (출원) 10-2022-0141010 (Oct 28, 2022). (환경부 100%)
6. Young-Pil Kim, Eun Song Lee. 비스페놀 A 특이적 핵산 압타머 및 이의 용도 (Bisphenol A-specific nucleic acid aptamer and using thereof). KR Patent Application (출원) 10-2020-0076675 (Jun 23, 2020). (INST 50%, 기초융 50%)
5. Young-Pil Kim, Kyung Jin Lee. 생물발광기반 활성산소 유도 융합단백질을 유효성분으로 포함하는 암전이 억제용 약학적 조성물 (Pharmaceutical composition for inhibiting cancer metastasis comprising bioluminescence based reactive oxygen species induced fusion protein as an active ingradient). KR Patent Application (출원) 10-2020-0022983 (Feb 25, 2020).
4. Jin-Won Lee, Myung Chan Gye, Young-Pil Kim, Su-Hyun Ryu. 비스페놀 A와의 결합력이 향상된 돌연변이 에스트로겐 수용체 단백질 및 이를 이용한 박테리아 균주 (Mutant estrogen receptor protein having improved binding capacity for bisphenol A and bacterial strain using the same). KR Patent Application (출원) No. 10-2018-0069808 (Jun 18, 2018). (환경호르몬 100%)
3. Jin-Won Lee, Myung Chan Gye, Young-Pil Kim, Su-Hyun Ryu, Yoo-Rae Kim. TIF2 공동조절인자 단백질을 이용한 박테리아 기반 바이오센서 및 이를 이용한 에스트로겐성 화합물의 검출 방법 (Bacteria-based biosensor using TIF2 protein and detecting method for estrogenic compounds using the same). KR Patent Application (출원) No. 10-2018-0043818 (Apr 16, 2018). (환경호르몬 100%)
2. Young-Pil Kim, Vinayakumar Gedi, Gae Baik Kim. CA125 특이적 압타머 (Cancer Antigen 125 Specific Aptamer). (우선권 주장 가출원 10-2017-0021069, Feb 16, 2017); KR Patent Application (출원) No. 10-2017-0066151 (May 29, 2017). (나노원천 50%+중점연구소 50%).
1. Houng Suk Kim, Myoung Jong Kwon, SeungJin Oh, Yungho Gwak, Young-Pil Kim, Ji-In Park, and EonSeon Jin. 결빙방지 부재 (Antifreeze Member). KR Patent Application (출원) No. 10-2014-0031677 (Mar 18, 2014). (착상저감 삼성과제 100%)
Domestic Patent (Registration)
28. Young-Pil Kim, Miso Kim. 광감작단백질 및 기질을 이용한 항산화물질 스크리닝 조성물 및 이의 방법 (A Composition for antioxidant screening using protein based photosensitizer and substrate and method thereof). KR Patent Application (출원) 10-2020-0041787 (Apr 06, 2020). KR Patent (등록) No. 10-2530047 (May 02, 2023) (베트남 과제 100%)
27. Young-Pil Kim, Jin-Won Lee, Jin Oh Lee, Yoon-Mo Yang, Tae-Wuk Kim. 산화환원조절 단백질을 포함한 바이오티올 검출용 조성물 (Composition for detection of biothiols comprising redox-regulating proteins). (우선권 주장 가출원 10-2016-0146831, Nov 04, 2016); KR Patent Application (출원) No. 10-2017-0144833 (Nov 01, 2017). KR Patent (등록) No. 10-2451039 (Sep 29, 2022) (삼성미래기술육성사업과제 100%)
26. Young-Pil Kim, Eun Song Lee, Tae-Wuk Kim. 금나노입자-SELEX에 기초한 표적특이적 압타머 선별법 (Method for screening target-specific aptamers based on gold nanoparticle-assisted SELEX). (우선권 주장 가출원, No. 10-2019-0099881, Aug 14, 2019). KR Patent Application (출원) 10-2020-0099798 (Aug 10, 2020). KR Patent (등록) No. 10-2442161 (Sep 05, 2022) (INST 중점 50%, 기초융 중점 50%)
25. Young-Pil Kim, Eun Hye Kim. 암세포 사멸 조성물 및 이의 용도 (A Composition for cancer cell death and its use). (우선권 주장 가출원 No. 10-2018-0126301, Oct 22, 2018). KR Patent Application (출원) 10-2019-0131285 (Oct 22, 2019). KR Patent Application (분할출원) 10-2021-0107105 (Aug13, 2021). KR Patent (등록) No. 10-2395704 (May 03, 2022) (중견생물발광 과제 100%)
24. Young-Pil Kim, Myung Chan Gye, Eunsong Lee, Gye Baik Kim. 비색-형광 혼합 모드를 이용한 환경호르몬 검출 방법 (Methods for detecting endocrine disruptors using dual modes of colorimetric and fluorometric analysis). (우선권 주장 가출원 Jan 31, 2017. No. 10-2017-0013847 (1차) / Jun 05, 2017. No. 10-2017-0069609 (2차)), KR Patent Application (출원) No. 10-2018-0012278 (Jan 31, 2018). KR Patent (등록) No. 10-2256570 (May 20, 2021) (환경호르몬 100%)
23. Young-Pil Kim, Eun Song Lee, Miso Kim, Chang-Hwan Park, Eun-Hye Lee, Jin Saem Lee. 신규 성상교세포 특이적 핵산 앱타머 및 이의 용도 (Astrocyte-specific nucleic acid aptamer and use thereof). (우선권 주장 가출원 No. 10-2018-0122835, Oct 15, 2018). KR Patent Application (출원) 10-2019-0108924 (Sep 03, 2019). KR Patent (등록) No. 10-2218267 (Feb 16, 2021) (바이오의료기술사업 100%)
22. Young-Pil Kim, Myung Chan Gye, Ju Tae Seo, Jin Oh Lee, Long Duc Nguyen. 루시페라아제 발광프로브를 이용한 효소 활성 분석법 (Method for analyzing proteinase activity using luciferase). (우선권 주장 가출원, No. 10-2018-0026770, Mar 07, 2018) KR Patent Application (출원) No. 10-2019-0005222 (Jan 15, 2019). KR Patent (등록) No. 10-2121863 (Jun 05, 2020) (보건부 저출산대응 의료기술개발과제 100%)
21. Jin-Won Lee, Myung Chan Gye, Young-Pil Kim, Su-Hyun Ryu. 에스트로겐성 화합물의 검출능을 갖는 아데닐레이트 사이클레이스 기반의 박테리아 균주 및 이를 이용한 에스트로겐성 화합물의 검출 방법 (Adenylate cyclase-based bacterial strain for the detection of estrogenic compounds and a method for detecting estrogenic compounds using the same). (우선권 주장 가출원 No. 10-2017-0043810 (Apr 16, 2017) KR Patent Application (출원) No. 10-2018-0068888 (Jun 15, 2018). KR Patent (등록) No. 10-2083729 (Feb 25, 2020) (환경호르몬 100%).
20. Young-Pil Kim, Hawon Lee. 프로테아제 활성 분석용 프로브 및 이를 이용한 분석 방법 (A probe for analyzing the protease activity and detection method of protease using the same). ((우선권 주장 출원 No. 10-2017-0043695 (Apr 04, 2017), KR Patent Application (출원) No. 10-2018-0039131 (Apr 04, 2018). KR Patent (등록) No. 10-2018249 (Sep 04, 2019) (중견연구(공명) 100%).
19. Young-Pil Kim, Vinayakumar Gedi, Jin Oh Lee, Eun Hye Kim. 생물발광 강도가 증폭된 변이 가우시아 루시퍼라아제 (Mutant Gaussia Luciferase with Enhanced Bioluminescence Intensity). KR Patent Application (출원) No. 10-2017-0032655 (Mar 15, 2017). KR Patent (등록) No. 10-2018248 (Aug 29, 2019). (중견연구(공명) 100%).
18. Young-Pil Kim, Hawon Lee, Haiwon Lee, Soo-Young Yun, Kyung-Cheol Moon. 핵산 효소를 이용한 전립선암 유발 유전자 검출용 프라이머 세트, 검출용 조성물 및 이를 이용한 전립선암 바이오마커의 검출 방법 (Primer set for detecting PCA3 and PSA using DNAzyme, and composition, method using the same). KR Patent Application (출원) No. 10-2017-0015457 (Feb 03, 2017). KR Patent (등록) No. 10-1975412 (Apr 29, 2019). (나노원천 50%+중점연구소 50%).
17. Young-Pil Kim, Myung Chan Gye, Bomi Choi, Hoseok Choi, Ju Tae Seo. 정자의 활성 측정방법 (Method for detecting sperm activeness). KR Patent Application (출원) No. 10-2016-0060357 (May 17, 2016). KR Patent (등록) No. 10-1969445 (Apr 10, 2019). (보건부 저출산대응 의료기술개발과제 100%)
16. Jin-Won Lee, Myung Chan Gye, Su-Hyun Ryu, Young-Pil Kim. 에스트로겐성 화합물의 검출을 위한 유전자 변이 박테리아 균주 및 이를 이용한 에스트로겐성 화합물의 검출 방법 (Genetically modified bacterial strain for the detection of estrogenic compounds, and detection method for estrogenic compounds using the strain). KR Patent Application (출원) No. 10-2016-0038444 (Mar 30, 2016). KR Patent (등록) No. 10-1925676 (Nov 29, 2018). (환경호르몬 100%)
15. Young-Pil Kim, Dong Yun Lee, Eun Hye Kim, Eun-Song Lee. 핵산효소를 이용한 눈물 내 나트륨 이온을 검출하기 위한 조성물 및 이를 이용한 나트륨 이온 검출 방법 (Composition for detecting sodium ion using DNAzyme and method for detecting sodium ion using thereof). KR Patent Application (출원) No. 10-2017-0019973 (Feb 04, 2017). KR Patent (등록) No. 10-1919365 (Nov 12, 2018). (바이오의료기술/눈물과제 100%).
14. Young-Pil Kim, Bu-Taek Lim, Jun Hyung Lim, Geun Chul Park, Jin Ho Joo. 생물발광 공명에너지 전이 유도용 나노구조체 및 이를 이용한 생물발광 공명 에너지 전이 시스템 (Nanostructures for Inducing BRET and BRET System Using the Same). KR Patent Application (출원) No. 10-2015-0074187 (May 27, 2015). KR Patent (등록) No. 10-1802325 (Nov 22, 2017). (중견핵심 50% +중점연구소 50%)
13. Young-Pil Kim and Kyung-Hyun Lee. 프로틴 카이네이즈 A 기질 인산화펩타이드에 결합하는 알엔에이 앱타머 (Phohsphorylated Peptide-Specific RNA Aptamer). KR Patent Application (출원) No. 10-2014-0155617 (Nov 10, 2014). KR Patent (등록) No. 10-1750407 (Jun 19, 2017). (중견핵심 50%+나노원천 50%)
12. Simon Song, Young-Pil Kim, Nak Chul Choi, Hoseok Choi, Butaek Lim. 단백질 인산화 효소 또는 탈인산화 효소 활성 측정용 미세유체칩 및 이를 이용한 효소활성 측정 방법 (Microfluidic Chip for Determining the Activities of Protein Kinases or Phosphatases and Determining Methods Using the Same). KR Patent Application (출원) No. 10-2015-0029717 (Mar 03, 2015). KR Patent (등록) No. 10-1743126 (May 29, 2017). (중점연구소 100%)
11. Young-Pil Kim, Jin Oh Lee, Gae Baik Kim, Butaek Lim. 탈인산화 또는 인산화 효소 활성 검출용 조성물 및 검출 방법 (Phosphatase or Kinase Activity Detection Composition and Detection Method). KR Patent Application (출원) No. 10-2014-0184843 (Dec 19, 2014). KR Patent (등록) No. 10-1683544 (Dec 1, 2016). (중견핵심 50%+나노원천 50%)
10. Young-Pil Kim and Gae Baik Kim. 단백질 분해효소 활성 분석방법 및 응용 (Method for analyzing the protease activity and the application thereof). KR Patent (등록) No. 10-1448353 (Sep 30, 2014). (일반연구사업 100%)
9. Young-Pil Kim, EonSeon Jin, Ji-In Park, Yunho Gwak, Hak Jun Kim, Jun Hyuck Lee. 동결방지단백질의 활성 분석 방법 및 그 응용 (Method for analyzing the activity of the anti-freezing protein and the application thereof). KR Patent (등록) No. 10-1417367 (Jul 2, 2014). (극지 PAP과제 100%)
8. Young-Pil Kim and Tae Geol Lee. 이차이온 질량 분석용 바이오 칩 및 이의 제조방법 (Bio-chip for Secondary Ion Mass Spectroscopy and the Fabrication Method thereof). KR Patent (등록) No. 10-1321747 (Oct 18, 2013).
[Before Hanyang Univ.]
7. Hak-Sung Kim, Young-Pil Kim, Sungyoung Park, Eunkeu Oh. 당단백질 분석용 바이오칩 세트 (Nanoparticle-based biochip set for detecting glycoproteins). KR Patent No. 10-0970584 (Jul 9, 2010).
6. Hak-Sung Kim, Young-Pil Kim, Jang-Hyuk Ahn. 저농도의 마이코톡신 측정방법 (Method for assaying mycotoxin). KR Patent No. 10-0948589 (Mar 12, 2010).
5. Hak-Sung Kim, Young-Pil Kim, Young-Hee Oh, Eunkeu Oh, Min-Kyu Han. Quantum dot-based biochip and method for assaying hydrolytic proteins using the same. KR Patent No. 10-0883547 (Feb 6, 2009).
4. Hak-Sung Kim, Young-Pil Kim, Young-Hee Oh. Eunkeu Oh. Detection method for the reaction between biomolecules and protein using biochip based on the monolayer of gold nanoparticles. KR Patent No. 10-0869909 (Nov 17, 2008).
3. Hak-Sung Kim, Young-Pil Kim, Dohoon Lee, Yunxian Piao, Jong Shin Yoo, Taeghwan Hyun. Method for enrichment and desalting of peptides using magnetic mesoporous carbon foams, and application thereof to mass spectrometric analysis. KR Patent No. 10-0784479 (Dec 4, 2007).
2. Hak-Sung Kim, Young-Pil Kim, Eunkeu Oh, Mi-Young Hong, Dohoon Lee, Tae Geol Lee, Dae Won Moon. Novel construction of gold nanoparticle-based peptide chip, and assaying enzyme activity and inhibitor effect using secondary ion mass spectrometric analysis thereof. KR Patent No. 10-070723 (Jul 12, 2007).
1. Jong Man Park, Hyung Joo Kim, Hee Jin Yang, Moon Sik Hyun, Young-Pil Kim, Tae Woo Cho. Composite electrode for COD measurement. KR Patent No. 10-0623933 (Sep 7, 2006).
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