Liquid Chromatography (LC) is a powerful analytical separation technique used across many scientific fields, including pharmaceuticals, environmental science, and the food industry. Projects in the Stoll Laboratory focus on deepening fundamental understanding of multiple aspects of liquid chromatography, including retention mechanisms, separation dynamics, and instrument design. Ultimately we aim to use this deepened understanding to improve LC techniques (speed, reliability, and cost effectiveness) so that researchers using the technique can answer their scientific questions better, faster, and for less cost. Currently, we are particularly interested in developing predictive models for LC retention that are accurate enough to be useful in method development, as well as our first love, multi-dimensional separations.