Publications
Journal Papers
Naoki Fukutake, Terumasa Ito, Kozue Kanno, Shogo Toda, and Kazuhiko Misawa, "Pupil-engineered coherent anti-Stokes Raman scattering spectroscopy," Optics Communications 552, 130076 (2023).
https://doi.org/10.1016/j.optcom.2023.130076Hao-Keng Wei, Hironori Ito, Wei-Hong Huang, Zai-Wen Chen, Ying-Kuan Ko, Chien-Ming Tu, Atsushi Yabushita, Kazuhiko Misawa, and Chih-Wei Luo, "Few-cycle THz wave manipulation with a high degree of freedom via f-t modulation," Optics Letters 48, 1016-1019 (2023).
https://doi.org/10.1364/OL.479000井口 里紗, 伊藤 輝将, 三沢 和彦, “ラマン分光を使った皮膚浸透性の見える化技術” Fragrance Journal 50, no. 6, 22-25 (2022).
Risa Iguchi, Yoji Nishi, Tsuyoshi Ogihara, Terumasa Ito, Fumiaki Matsuoka, and Kazuhiko Misawa, “Time-course quantitative mapping of caffeine within the epidermis, using high-contrast pump–probe stimulated Raman scattering microscopy,” Skin Research and Technology 28, 47-53 (2022).
https://doi.org/10.1111/srt.13088Terumasa Ito, Risa Iguchi, Fumiaki Matsuoka, Yoji Nishi, Tsuyoshi Ogihara, and Kazuhiko Misawa, “Label-free skin penetration analysis using time-resolved, phase-modulated stimulated Raman scattering microscopy,” Biomedical Optics Express 12, 6545-6557 (2021).
https://doi.org/10.1364/BOE.436142
Featured in "Spotlight on Optics" of Optica Publishing Group伊藤 輝将, “パルス波形整形を用いた誘導ラマン散乱顕微鏡,” 光学 49, no. 2, 66-72 (2020).
http://myosj.or.jp/kogaku/backnumber/49-02/Hao-Keng Wei, Hironori Ito, Kazuhiko Misawa, and Chih-Wei Luo, "Generation and manipulation of polarization-twisting dual pulses with a high degree of freedom," Optics Letters 45, 6663-6666 (2020).
https://doi.org/10.1364/OL.409672Dominik Kinschel, Camila Bacellar, Oliviero Cannelli, Boris Sorokin, Tetsuo Katayama, Giulia F. Mancini, Jérémy R. Rouxel, Yuki Obara, Junichi Nishitani, Hironori Ito, Terumasa Ito, Naoya Kurahashi, Chika Higashimura, Shotaro Kudo, Theo Keane, Frederico A. Lima, Wojciech Gawelda, Peter Zalden, Sebastian Schulz, James M. Budarz, Dmitry Khakhulin, Andreas Galler, Christian Bressler, Christopher J. Milne, Thomas Penfold, Makina Yabashi, Toshinori Suzuki, Kazuhiko Misawa and Majed Chergui “Femtosecond X-ray emission study of the spin cross-over dynamics in haem proteins,” Nature Communications 11, 4145 (2020).
https://doi.org/10.1038/s41467-020-17923-wHironori Ito, Tetsuo Nakano, Shintaro Nomura, and Kazuhiko Misawa, "Polarization envelope helicity dependent photovoltage in GaAs/Al0.3Ga0.7As modulation-doped quantum well," Optics Express 27, 28091-28103 (2019).
https://doi.org/10.1364/OE.27.028091Terumasa Ito, Yuki Obara, and Kazuhiko Misawa, “Invited Article: Spectral focusing with asymmetric pulses for high-contrast pump–probe stimulated Raman scattering microscopy,” APL Photonics 3, 092405 (2018).
https://doi.org/10.1063/1.5030053Terumasa Ito, Yuki Obara and Kazuhiko Misawa, “Single-beam phase-modulated stimulated Raman scattering microscopy with spectrally focused detection,” Journal of the Optical Society of America B 34, 1004-1015 (2017).
https://doi.org/10.1364/JOSAB.34.001004Yuki Obara, Hironori Ito, Terumasa Ito, Naoya Kurahashi, Stephan Thürmer, Hiroki Tanaka, Tetsuo Katayama, Tadashi Togashi, Shigeki Owada, Yo-ichi Yamamoto, Shutaro Karashima, Junichi Nishitani, Makina Yabashi, Toshinori Suzuki and Kazuhiko Misawa, “Femtosecond time-resolved X-ray absorption spectroscopy of anatase TiO2 nanoparticles using XFEL,” Structural Dynamics 4, 044033 (2017).
https://doi.org/10.1063/1.4989862
Conference Presentations
[Invited] Terumasa Ito, "High-Contrast Raman Imaging Using Temporal Filtering," Laser Display and Lighting Conference 2024 (LDC2024), Optics & Photonics International Congress (OPIC), LDC13-01, Apr. 26 (2024).
Shuri Kozuka, Shundai Yamamoto, Terumasa Ito, and Kazuhiko Misawa, "Peak Power Dependence in Bacterial Inactivation Using UV-C Pulsed Light Irradiation," Optica Biophotonics Congress: Biomedical Optics 2024, TW3B.6, Apr. 10 (2024).
Haruki Kanae, Terumasa Ito, Kaori Tsukakoshi, Shintaro Inaba, Mizuki Tomizawa, Kaustav Das, Kazunori Ikebukuro, and Kazuhiko Misawa, "Detection of Structural Changes in DNA Due to Methylation Using Raman Spectroscopy," Optica Biophotonics Congress: Biomedical Optics 2024, OW1D.4, Apr. 10 (2024).
Terumasa Ito, Fumiaki Matsuoka, and Kazuhiko Misawa, "Phase locking of temporally filtered SRS signals for label-free small-molecule detection at sub-millimolar concentrations," SPIE Photonic West BIOS 2024, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, 12855-10, Jan. 27 (2024).
Kanako Tajima, Katsuya Iwata, Masaharu Kameda, Kazuhiko Misawa, and Terumasa Ito, "Pulse shaping with dispersion engineered optical filters for single-pass narrowband second harmonic generation," SPIE Photonic West LASE 2024, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XXV, 12875-19, Jan. 28 (2024).
Shundai Yamamoto, Kazuhiko Misawa, and Hideki Abe, "Suppression of the tailing effect for pathogen inactivation with UVC ultrashort pulsed light," SPIE Photonic West BIOS 2024, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2024, 12822-37, Jan. 30 (2024).
Kaustav Das, Fawzia Novianti, Ken Komatsu, Terumasa Ito, and Kazuhiko Misawa, "Identification of earliest point for detection of plant virus infection through Raman spectroscopy and principal component analysis," SPIE Photonic West LASE 2024, Photonic Technologies in Plant and Agricultural Science II, 12879-13, Jan. 31 (2024).
Kyosuke Makino, Kazuhiko Misawa, Terumasa Ito, and Hironori Ito, "Non-thermal protein structural change by THz pulsed light irradiation," SPIE Photonic West OPTO 2024, Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications XVIII, 12885-61, Feb. 1 (2024).
伊藤 輝将, 三沢 和彦, "パルス波形整形を用いた薬剤分子の誘導ラマン散乱イメージング," Optics & Photonics Japan 2023, 28pG4, Nov. 28 (2023).
金江 陽希, 伊藤 輝将, 塚越 かおり, カウスタフ ダス, 池袋 一典, 三沢 和彦, "ラマン分光法を用いたDNAのメチル化による構造変化の検出," Optics & Photonics Japan 2023, 28pG5, Nov. 28 (2023).
松岡 史晃, 伊藤 輝将, "量子スクイージングによる分子と光学共振器の振動結合増強," Optics & Photonics Japan 2023, 29pF1, Nov. 29 (2023)
宮田 紫帆, 入谷 京, 武本 智嗣, 神邉 淳, 伊藤 輝将, 山本 ゆき, 三沢 和彦, 永岡 謙太郎, "乳房炎早期発見へ向けたラマン顕微鏡の応用," 第28回日本乳房炎研究会学術集会, 演題-7, Oct. 21 (2023).
Fumiaki Matsuoka and Terumasa Ito, "Enhancing Vibrational Coupling via Squeezing of Quantum Vacuum Field," ACS Fall 2023, 3915115, Aug. 15 (2023).
Kaustav Das, Fawzia Novianti, Ken Komatsu, Terumasa Ito and Kazuhiko Misawa, "Systematic detection and monitoring of plant virus infection using Raman spectroscopy and principal component analysis," ACS Fall 2023, 3925803, Aug. 13 (2023).
Terumasa Ito, "Stimulated Raman Scattering Microscopy for High-Contrast Drug Imaging," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Inv. 01 (2023).
Fumiaki Matsuoka, "Quantum Enhancement for Strength of Vibrational Coupling Between an Optical Cavity and Molecules," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Inv. 08 (2023).
Kaustav Das, Fawzia Novianti, Ken Komatsu, Terumasa Ito and Kazuhiko Misawa, "Monitoring the Progression of Virus Infection in Plants Using Raman Spectroscopy and Principal Component Analysis," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Inv. 09 (2023).
Haruki Kanae and Kazuhiko Misawa, "Detection of Structural Changes in DNA Due to Methylation Using Raman Spectroscopy," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 01 (2023).
Daichi Igarashi, Terumasa Ito, Daisuke Yoshino, and Kazuhiko Misawa, "Toward Discovery of Biomarkers for New Diagnostic Techniques of IgA Nephropathy," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 02 (2023).
Shundai Yamamoto, Hideki Abe and Kazuhiko Misawa, "Suppression of the Tailing Effect for Pathogen Inactivation with UVC Ultrashort Pulsed Light," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 03 (2023).
Kohei Eguchi, Terumasa Ito, Daisuke Yoshino and Kazuhiko Misawa, "Acquisition of Raman Spectra of Foamed Macrophages for Early Diagnosis of Atherosclerosis", the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 04 (2023).
Yuki Sekiya and Terumasa Ito, "Transdermal Penetration of Self-Dissolving Microneedles Using Coherent Raman Scattering Microscopy," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 05 (2023).
Yu Okano, Ken Okano and Kazuhiko Misawa,"Electrolysis Measurements and Evaluation of Boron-Doped Diamond-Coated Electrode Materials for Fuel Cells," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 06 (2023).
Kyosuke Makino and Kazuhiko Misawa,"Non-Thermal Protein Structural Change by THz Pulsed Light Irradiation," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 07 (2023).
Kei Ogiriyama and Kazuhiko Misawa,"Evaluation of the Ability of Various Peptoids to Inhibit Amyloid Beta Aggregation," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 08 (2023)
Shuri Kozuka, Shundai Yamamoto and Terumasa Ito, "Differential Effects of Continuous and Pulsed UV-C Light on Bacterial Inactivation in Platelet Concentrates," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 09 (2023)
Ryo Fujisawa and Terumasa Ito,"Real-Time Monitoring of Aspirin Metabolism Using Raman Microscopy," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 10 (2023).
Noa Saito and Terumasa Ito, "Analysis of Celluer Transport of Odor Molecules Using Coherent Raman Scattering Microscopy," the 1st NYCU-TUAT-UY International Symposium, Laser Control Technology for Innovation of Biomedical and Electronics, Pos. 11 (2023)
Miyako Iritani, Terumasa Ito, and Kazuhiko Misawa, "Steroid penetration through different tissue barriers visualized by phase-modulated stimulated Raman scattering microscopy," the European Conferences on Biomedical Optics (ECBO) 2023, 12630-6, Jun. 28 (2023).
[Invited] 三沢 和彦, "時間分解位相制御誘導ラマン散乱顕微鏡を用いた薬剤小分子の無標識皮膚浸透動態測定," 日本薬剤学会 第12回経皮投与製剤FGシンポジウム, Feb. 22 (2023).
Terumasa Ito, Fumiaki Matsuoka, and Kazuhiko Misawa, "Temporal optical filtering: Finding a needle in the Raman haystack," SPIE Photonic West BIOS 2023, Visualizing and Quantifying Drug Distribution in Tissue VII, 12357-15, Jan. 28 (2023).
Kaustav Das, Terumasa Ito, and Kazuhiko Misawa, "Investigation on baseline fitting for Raman spectroscopy of living cells and its impact on principal component analysis," SPIE Photonic West BIOS 2023, Multiscale Imaging and Spectroscopy IV, 12363-07, Jan. 28 (2023).
[Invited] 伊藤 輝将, "位相変調機能を有する非線形ラマン顕微鏡による薬物動態観察," レーザー学会学術講演会第43回年次大会, S08-18p-VIII, Jan 18 (2022).
伊藤 輝将, 三沢 和彦, "誘導ラマン散乱イメージングにおける背景光抑制手法の時間フィルタ特性," Optics & Photonics Japan 2022, 14aE2, Nov. 14 (2022).
今泉 公宏, 伊藤 輝将, 吉野 大輔, 三沢 和彦, "光ピンセットで捕捉した浮遊細胞のラマン分光法による分化判定," Optics & Photonics Japan 2022, 14aE3, Nov. 14 (2022).
齊藤 輝正, 伊藤 宙陛, 伊藤 輝将, 三沢 和彦, "位相ロック機構によって安定化されたテラヘルツ領域の偏光波形制御パルスの生成," Optics & Photonics Japan 2022, 14aC10, Nov. 14 (2022).
Risa Iguchi, Terumasa Ito, Yoji Nishi, Tsuyoshi Ogihara, and Kazuhiko Misawa, "Imaging skin-penetration dynamics of caffeine under various conditions by using a high-resolution non-invasive analytical method," The 32nd IFSCC Congress, Lecture #57, Sep. 21 (2022).
Saori Watanabe, Fumiaki Matsuoka, Terumasa Ito, and Kazuhiko Misawa, "Analysis of sunscreen penetration in skin using phase-modulated stimulated Raman scattering microscopy," Biophotonics Congress: Biomedical Optics 2022, JM3A.50, Apr. 26 (2022).
Miyako Iritani, Terumasa Ito, Kentaro Nagaoka, and Kazuhiko Misawa "Discrimination of mastitis history in dairy cows by Raman spectroscopy of milk components", SPIE Photonic West BIOS 2022, Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry, 11957-57, Mar. 7 (2022).
Yu Okano, Ken Okano, and Kazuhiko Misawa "Evaluation of conductivity in graphitized CVD-grown diamonds by Raman micro-spectroscopy", SPIE Photonic West LASE 2022, Nanoscale and Quantum Materials: From Synthesis and Laser Processing to Applications 2022, 11990-02, Mar. 4 (2022).
[Invited] Terumasa Ito, “Coherent Raman scattering microscopy: ultrafast optics for high-contrast drug imaging,” International Symposium on Imaging, Sensing, and Optical Memory 2021, Mo-E-01, Oct. 4 (2021).
Sora Tomita, Terumasa Ito, Kazuyuki Iwaikawa, Gen Hayase, Daisuke Yoshino, and Kazuhiko Misawa, "Quantitative measurement of low-concentration analytes using Raman spectroscopy during droplet evaporation for therapeutic drug monitoring," the European Conferences on Biomedical Optics (ECBO) 2021, EW3A.2, June 23 (2021).
Marin Saiga, Yuki Obara, Hideki Abe, and Kazuhiko Misawa, "Bacterial inactivation in platelet concentrates using ultrashort pulsed laser," the European Conferences on Biomedical Optics (ECBO) 2021, EM1A.3 (2021).
Hao-Keng Wei, Hironori Ito, Kazuhiko Misawa, and Chih-Wei Luo, "Polarization twisting dual-pulse generation," CLEO: Science and Innovations, STu1D.4, May 11 (2021).
Terumasa Ito, Miyako Iritani, Fumiaki Matsuoka, and Kazuhiko Misawa "Time-resolved stimulated Raman scattering microscopy for robust quantitative chemical measurements in tissue," SPIE Photonics West BIOS 2021, Advanced Chemical Microscopy for Life Science and Translational Medicine, 116560G, Mar. 5 (2021).
Terumasa Ito, Risa Iguchi, Fumiaki Matsuoka, Yoji Nishi, Tsuyoshi Ogihara and Kazuhiko Misawa, “High-Contrast Depth Imaging of Skin Moisturizing Agent Using Phase-Modulated Stimulated Raman Scattering,” 14th Pacific Rim Conference on Lasers and Electro-Optics, C12D_2 Aug. 5 (2020).
Masahiro Ikejiri, Mami Oba, Terumasa Ito, Rongduo Wen, Tetsuya Mizutani and Kazuhiko Misawa, “Detection of Viral Infection and Subsequent Apoptosis in Cells by Raman Scattering Microspectroscopy,” 14th Pacific Rim Conference on Lasers and Electro-Optics, P3_18 (2020).
Katsuya Iwata, Yoichi Saito, Terumasa Ito, Yuki Obara, Masaharu Kameda and Kazuhiko Misawa, “High-Pressure Gas Measurement Using Time-Resolved Rotational CARS with Temporally Asymmetric Pulses,” 14th Pacific Rim Conference on Lasers and Electro-Optics, C6D_2 (2020).
大場 真己, 池尻 将拓, 伊藤 輝将, 文 榕鐸, 菊池 風花, 水谷 哲也, 三沢 和彦, "ラマン分光法を利用したウイルス感染初期細胞の検出について," 第163回日本獣医学会学術集会, DVO-32 (2020).
Risa Iguchi, Yoji Nishi, Tsuyoshi Ogihara, Terumasa Ito, Fumiaki Matsuoka, and Kazuhiko Misawa “Comparison of heterogeneous formulations by real time label free profiling of actives within skin using high contrast pump probe stimulated Raman scattering microscopy,” the 31st IFSCC Congress 2020 (2020).
Patents
Kazuhiko Misawa and Terumasa Ito, Optical pulse pair generation device, light detection device, and light detection method, WO2019220863A1, PCT/JP2019/016860, JP2018-093067.
Kazuhiko Misawa and Terumasa Ito, Optical detection device and optical detection method, PCT/JP2021/007554
Kazuhiko Misawa and Terumasa Ito, Optical detection device and optical detection method, PCT/JP2020/048526.
三沢 和彦、伊藤 輝将、小原 祐樹、林 真澄 「光検出装置、光検出方法および光検出プログラム」 特許登録 JP6765648 (2020).
Books
三沢 和彦,芦原聡「工学系のためのレーザー物理入門」講談社 (2020) ISBN-13: 978-4061532816
三沢 和彦「理工系のための解く! 振動・波動」講談社 (2009) ISBN-13: 978-4061557826
三沢 和彦「理工系のための解く! 熱力学」講談社 (2007) ISBN-13: 978-4061557727