Dakshanamurthy Laboratory

Welcome to the Laboratory of Sivanesan Dakshanamurthy, located at the Lombardi Comprehensive Cancer Center, part of the Georgetown University Medical Center.

Our research concerns Big Data analytics, High-throughput chemo- and clinical informatics, Systems Engineering, Systems Networks & Pharmacology, Big Database development, Chemicals and Materials simulations, drug-repurposing, drug-protein interactions, molecular and nano-technology simulations.

Many of these research interests include the design of new chemicals, measuring or calculating the activity, functions, and toxicity of chemicals and drugs in-silico and in biological media. Applications include pharmaceuticals, and industrial materials.

photo of a woman looking at shelves of publications

Lab members have recently published in:

  • Concurrency and Computation[1]
  • Expert Review of Clinical Pharmacology[2]
  • J. Immunology [3]
photo showing a group of people working on computers

Find out more about our lab director, Sivanesan Dakshanamurthy.

Current activate lab members include Oakland Peters and Naiem Issa.

Or take a look at past laboratory alumni.

photo of Georgetown University seal in a university building

The Dakshanamurthy laboratory has several opportunities available for driven and creative individuals, at undergraduate, graduate, and post-doctoral levels.

Find out more.

image from one of our lab projects

Our laboratory has several ongoing informatics projects, which include the CCCID freely available database and the TMFS drug-docking analysis method.

photo of a person working on a laptop computer

Find useful links about software, chemo- and bio- informatic tools used by our laboratory.

cover of the J.T.C.S. Journal

Dr. Dakshanamurthy is the founded and Editor-in-Chief of J.T.C.S., a journal addressing experimental and computer science issues in the context of the applied sciences.


1. Elllingson Sellings, Sivanesan Dakshanamurthy, Milton Brown, Smith, Jeremy C and Jerome Baudry. Accelerating Virtual High-Throughput Ligand Docking: Current Technology and Case Study on a Petascale Supercomputer. Concurrency and Computation: Practice and Experience Concurrency Computat.: Pract. Exper. (June 2013). doi: 10.1002/cpe.30702. Issa, N. T., Kruger, J., Byers, S. W., & Dakshanamurthy, S. (2013). Drug repurposing a reality: from computers to the clinic. Expert review of clinical pharmacology, 6(2), 95-97. doi: 10.1586/ECP.12.793. William R. Frazier, Noriko Steiner, Lihua Hou, Sivanesan Dakshanamurthy, Carolyn Katovich Hurley. Allelic Variation in KIR2DL3 Generates a KIR2DL2-like Receptor with Increased Binding to Its HLA-C Ligand. J Immunol. 2013 Jun 15;190(12):6198-208. doi: 10.4049/jimmunol.1300464