Welcome

Our laboratory at Georgetown University focuses on uncovering the factors that govern tissue development, maintenance, functional decline, and repair/regeneration by advancing innovative tissue engineering and regenerative approaches. Our primary research areas include:

a) Development and Utilization of tissue-on-a-chip platforms for dental/craniofacial, kidney and bone diseases

b) Investigation of biochemical, biophysical, and molecular mechanisms underlying tissue function

c) Application of additive manufacturing and 3D printing technologies for bone regeneration 

 News:

Sept 2025: Recent Publication by Alimperti Lab: " Ascorbic Acid Modulates Collagen Properties in Glucocorticoid-Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation " was published at Advanced Healthcare Materials - Link Here

April 2025: Recent Publication by Alimperti Lab: " PLVAP: the new villain in glomerular endothelial cell injury " was published at American Journal of Physiology-Renal Physiology - Link Here

January 2025: Recent Publication by Alimperti Lab: " Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms " was published at Advanced Healthcare Materials- Link Here

December 2024: Recent Publication by Alimperti Lab: "Intellectual property training should be embedded in the biomedical education process" was published at Nature Biotechnology- Link Here

October 2023: Recent Publication by Alimperti Lab: " Re-epithelialization of Diabetic Skin and Mucosal Wounds is Rescued by Treatment with Epigenetic Inhibitors" was published at Diabetes- Link Here

October 2023: Recent Publication by Alimperti Lab: " A 3D biomimetic model of lymphatics reveals cell–cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex" was published at PNAS- Link Here

June 2023: Our Paper by Lee, E.J., et.al . “Mechanical Regulation of  Oral epithelial barrier function”  was published and is Cover at Bioengineering- Link Here

Contact us

Building D

4000 Reservoir Rd

Georgetown University

Washighton, DC, 20007

email: sa1940@georgetown.edu