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Structure-Based Mechanism and the Specificity of Human Galactosyl-transferase β3GalT5
Structure-Based Mechanism and the Specificity of Human Galactosyl-transferase β3GalT5
2025
Jennifer M. Lo, Chih-Chuan Kung, Ting-Jen Rachel Cheng, Chi-Huey Wong*, and Che Ma*
Journal of the American Chemical Society, 147(13), 10875-10885.
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Expression of Human β3GalT5–1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans
Expression of Human β3GalT5–1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans
2025
Chih-Chuan Kung, Jennifer M. Lo, Kuo-Shiang Liao, Chung-Yi Wu, Lu-Chun Cheng, Cinya Chung, Tsui-Ling Hsu, Che Ma*, and Chi-Huey Wong*
Journal of the American Chemical Society, 147(13), 10864-10874.
The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine
The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine
2024
Xiaorui Chen, Arpita Mohapatra, Hong Thuy Vy Nguyen, Lisa Schimanski, Tiong Kit Tan, Pramila Rijal, Cheng-Pin Chen, Shu-Hsing Cheng, Wen-Hsin Lee, Yu-Chi Chou, Alain R. Townsend, Che Ma, Kuan-Ying A. Huang*
PLOS Pathogens, 20(6), e1012246.
Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome
Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome
2023
Hong Thuy Vy Nguyen, Xiaorui Chen, Claudia Parada, An-Chi Luo, Orion Shih, U-Ser Jeng, Chia-Ying Huang, Yu-Ling Shih* & Che Ma*
Nature Communications, 14, 1903.
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
2023
Kuan-Ying A. Huang*, Xiaorui Chen, Arpita Mohapatra, Hong Thuy Vy Nguyen, Lisa Schimanski, Tiong Kit Tan, Pramila Rijal, Susan K. Vester, Rory A. Hills, Mark Howarth, Jennifer R. Keeffe, Alexander A. Cohen, Leesa M. Kakutani, Yi-Min Wu, Md Shahed-Al-Mahmud, Yu-Chi Chou, Pamela J. Bjorkman, Alain R. Townsend & Che Ma*
Nature Communications, 14, 311.
Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation
Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation
2022
Wen-Hsin Lee, Xiaorui Chen, I-Ju Liu, Jiin-Horng Lee, Chun-Mei Hu, Han-Chung Wu, Sheng-Kai Wang, Wen-Hwa Lee, Che Ma*
Cell Reports, 41(4), 111555.
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Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models
Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models
2022
Han-Yi Huang, Hsin-Yu Liao, Xiaorui Chen, Szu-Wen Wang, Cheng-Wei Cheng, Md. Shahed-Al-Mahmud, Yo-Min Liu, Arpita Mohapatra, Ting-Hua Chen, Jennifer M. Lo, Yi-Min Wu, Hsiu-Hua Ma, Yi-Hsuan Chang, Ho-Yang Tsai, Yu-Chi Chou, Yi-Ping Hsueh, Ching-Yen Tsai, Pau-Yi Huang, Sui-Yuan Chang, Tai-Ling Chao, Han-Chieh Kao, Ya-Min Tsai, Yen-Hui Chen, Chung-Yi Wu, Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Kuo-I Lin*, Che Ma*, Chi-Huey Wong*
Science Translational Medicine, 14, eabm0899.
A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells
A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells
2021
Yi-An Ko, Yueh-Hsiang Yu, Yen-Fei Wu, Yung-Chieh Tseng, Chia-Lin Chen, King-Siang Goh, Hsin-Yu Liao, Ting-Hua Chen, Ting-Jen Rachel Cheng, An-Suei Yang, Chi-Huey Wong, Che Ma*, Kuo-I Lin*
PLOS Pathogens, 17(8), e1009724.
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Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
2021
Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Yu-Pu Juang, Hsiu-Hua Ma, Ying-Ta Wu, Wen-Bin Yang, Cheng-Wei Cheng, Xiaorui Chen, Ting-Hung Chou, Jiun-Jie Shie, Wei-Chieh Cheng, Rong-Jie Chein, Shi-Shan Mao, Pi-Hui Liang*, Che Ma*, Shang-Cheng Hung*, and Chi-Huey Wong*
Proceedings of the National Academy of Sciences of the United States of America, 118(5), e2021579118
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A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2
A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2
2020
Yo-Min Liu, Md. Shahed-Al-Mahmud, Xiaorui Chen, Ting-Hua Chen, Kuo-Shiang Liao, Jennifer M. Lo, Yi-Min Wu, Meng-Chiao Ho, Chung-Yi Wu, Chi-Huey Wong, Jia-Tsrong Jan, Che Ma*
Cell Reports, 32(6), 108016
Better influenza vaccines: an industry perspective
Better influenza vaccines: an industry perspective
2020
Juine-Ruey Chen, Yo-Min Liu, Yung-Chieh Tseng & Che Ma*
Journal of Biomedical Science, 27(1), 33-44.
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Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective.
Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective.
2019
Xiaorui Chen, Chi-Huey Wong, and Che Ma*
ACS Infectious Diseases, 5(9) 1493-1504.
Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections.
Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections.
2019
Yung-Chieh Tseng, Chia-Yu Wu, Ming-Liang Liu, Ting-Hua Chen, Wan-Ling Chiang, Yueh-Hsiang Yu, Jia-Tsrong Jan, Kuo-I Lin, Chi-Huey Wong*, and Che Ma*
Proceedings of the National Academy of Sciences of the United States of America, 116(10), 4200-4205.
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