Inovapotek (2010) is devoted to providing R&D services to the cosmetic, pharmaceutical, medical devices and food supplements' industries. In January 2010, it was the first company that sought to obtain the U.Porto Spin-Off seal due to recognized merit and scientific excellence of the University of Porto." In its 9th year of activity inovapotek works with clients all over Europe, the United States, Canada, Japan and Australia, and continues to invest in its internationalization.
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Metablue (2013) took its first steps under the Masters in Innovation and Technological Entrepreneurship (MIETE). After the masters programme, the founders studied various technologies from the University of Porto and decided to embark on the development of a medical device that allows for the early diagnosis of otitis - the OTITEST. Metablue is dedicated to the commercialisation of medical devices, such as the Otitest, the Lipowise and the Digital Laryngoscope.
Biomode (2017-2022) is an innovative company in the biotechnology field, where the core activities are focused in the research, development and the commercialization of rapid diagnostic kits based on Peptide Nucleic Acid FISH technology for microbial detection in food and clinical samples. The company's initial focus is to certify its food products with the North American certification entity – AOAC. Two of its products, Probe4Monocytogenes and Probe4Cronobacter, are in the final stages of certification and another - Probe4Salmonella –is expected to enter the process quite soon.
EACT ERGO+ACTIVA (2017-2019) works with businesses and institutions to change and improve working behaviours, postures and environments. The company provides training and services based on ErgoCoaching – workplace Ergonomics through the practice of concepts of ergonomics, coaching, physical exercises and compensation and / or application of the principles of preventive physiotherapy. The methodology of this spin-off is ground-breaking in terms of transforming and consolidating healthier and more ergonomic habits, postures and movements. EACT was created in FADEUP (Faculty of Sports of the University of Porto), which in turn supported the company early on and, together, they have developed relevant know-how in the fields of Physiotherapy, Exercise and Ergonomics, giving EACT ERGO+ACTIVA a competitive edge in the market and making it a pioneer and reference in the areas in which it operates.
Immunethep (2017) is a biotechnology company born in the Abel Salazar Institute of Biomedical Sciences (ICBAS). This U.Porto spin-off is currently developing immunotherapies to fight bacterial infections. Immunethep is developing the only anti-bacterial vaccine that covers several bacteria, including bacteria known for their resistance to antibiotics: Gram-negative (E. coli and K. pneumoniae) and Gram-positive (S. aureus, S. pneumoniae, GBS). The vaccine is intended to prevent infections caused by these bacteria in the overall population but with a major focus in risk groups, for example, patients undergoing surgeries, elderly, diabetic and newborns.
FASTinov (2017) is an R&D-related start-up born in the academic context of U.Porto's Faculty of Medicine. Its patented technology makes it possible to perform antimicrobial tests much more quickly than using today's methods, in a highly accurate and much more informative way. "With this technology, we will be able to identify the primary resistance mechanisms of the microorganisms, which is fundamental to understanding their transmission, designing new therapies and ensuring safe and timely treatments to prevent mortality", says CEO Cidália Pina Vaz.
i-sensis perfume design (2017) specializes in the creation of personalized fragrances according to the clients' needs. These fragrances can then be applied in a olfactive marketing strategy, either by producing turn-key, private label perfumed products such as perfumes, candles, etc or by professional scenting of spaces using patented technology. The main market is Business 2 Business.
Medida (2017) Medicine, Education, Research, Development and Evaluation Services LDA acts in the development, evaluation and distribution of products and services for people with chronic diseases, especially for respiratory or allergic patients. The company's target market are healthcare providers and pharmaceutical companies. Currently, the company focuses in developing m-Health technologies, namely in sound and image processing from cell phone sensors for the monitoring of respiratory pathologies. The company was born out of work developed at CINTESIS and also from the Faculties of Medicine and Sciences of the University of Porto.
Tonic Easy Medical (2017) Company specialized in the area of digital mobile health, for safe and dedicated communication between doctors and professional health content. The target market for the spin-off is mainly European and Portuguese-speaking countries, consisting of both end-users, doctors and intermediaries: hospitals and other health organizations.
MITOTAG (2018) develops targeting systems to deliver antioxidants to mitochondria in order to protect them from the damaging effects of oxidative stress. This platform technology has applications in diverse areas, namely: as active ingredients for anti-aging cosmetics, active principles for the treatment of liver and neurodegenerative diseases, as well as supplements for animal feed.
Promptly (2019) is a portuguese outcomes analytics SME founded in 2017 by a group of physicians, with the ambition of making health systems rely increasingly in patient-centered outcomes. Their vision for the future of Healthcare is inspired by Value-based Healthcare principles that are garnering attention in several health systems around the world.
inSignals Neurotech Lda (2019) is a spin-off from University of Porto incorporated in 2019, aiming to explore the applied R&D results from from the BRAINlab/C-BER of INESC TEC on neuroengineering lead by Prof. João Paulo Cunha. The company is focused on bringing to the market technological solutions that are able to improve the diagnosis and treatment of neurological therapies, such as the iHandU technology that supports the assessment of motor symptoms in Parkinson's Disease.
WISIFY Tech Solutions (2019) develops solutions for the assessment of people's nutritional and physical status and is focused on medical, nutrition and sports professionals who need reliable and innovative tools to help them to improve the lives of their clients. The solution consists of a management platform, mobile applications and two devices: the LIPOWISE for localized assessment of body fat and GRIPWISE for evaluation of the strength of different muscular groups.
BIOFABICS (2020) is an R&D company specialized in 3D Biotissue Analogues. providing next-generation solutions for studying, mimicking, repairing and replacing living tissues and organs. The company derives its experience and knowledge through its team and in research and innovation activities.
iLoF (2020) is enabling a new era of personalized medicine, by using AI and photonics to build a cloud-based library of diseases biomarkers. The company is leveraging machine learning to drastically reduce the cost and time of drug discovery, and providing screening and stratification tools in an affordable, fast and portable way. Currently, they are tackling one of the biggest epidemic of our times: Alzheimer's.
Gripwise (2020) it the first integrated and connected system capable of the assessment and monitoring of Frailty in a simple and fast way, maintaining the energy and quality of life of the elderly and reducing costs. 60% of the elder population of Europe suffer of some level of physical frailty, and the estimated costs for the EU Health Care Systems are more than 81 Billion €/year. Preventive assessment of frailty could maintain quality of life and reduce costs, but it's complex.
MOOT (2020) developed a training support tool, regardless of it being technical, theoretical and/or practical, and also takes into account the physical condition (strength, mobility, flexibility) and well-being and health (physical, mental, social and spiritual) of dancers and other practitioners of modalities associated with movement. This tool is based on new technologies and runs on a bilingual digital platform.
ERGOFORM (2019) develops training plans on personalized ergonomic culture for the productive well-being of each company. Productive well-being is the balanced result between several aspects of physical, mental, and organizational ergonomics at work. Our goal is to transform conventional training into a participative and intuitive learning experience, facilitating the change of habits and making productive behaviors for different audiences credible.
Bioprospectum (2021) is a start-up that operates in the area of technological innovation. The company has a proprietary molecule bank generated from the prospection of biodiversity for bioactive molecules at national and international level. Potentially active molecules are identified by artificial intelligence tools and further tested for the development of new products, such as antioxidants, antimicrobial and anti-inflammatories. Moreover, the company offers scientific and technical consulting services. Other activities include the organization of scientific meetings and publishing the Journal of Global Innovation.
be-ergo (2021) Be-Ergo is a company dedicated to the promotion of Occupational Health with focus on the Corporate Performance. By way of actions carried out on the job, their intervention promotes the acquisition of safer and healthier habits and behaviors based on three essential areas: Ergonomics, Physiotherapy and Physical Exercise. With more than 10 years of experience, this spin-off enhances productivity and corporate well-being, while also prevents staff illness.
DigestAID (2022) leverages the combination of the enthusiasm and expertise of young and senior gastroenterologists with the drive for innovation and skillfulness of an experienced engineering team to take advantage of AI technologies. DigestAID is focused on the development of accurate deep learning solutions for the detection of digestive lesions. Our aim is to improve GI healthcare.
AGIT (2023) Agit developed a technology that tracks physical exercise in real-time using the smartphone camera. Our app provides live feedback about exercise performance and enables authentic competitions and social experience.
Regenera Sciences (2023) Development of cell-based therapies for veterinarian regenerative medicine in a One Health perspective.
FetalDisc (2023) provides the first regenerative fetal-inspired solution to treat low back pain through a minimally-invasive application - FETALIX. This biomaterial provides veterinaries and orthopaedic surgeons a new and preventive treatment for intervertebral disc degeneration while promoting circular economy by creating value from animal waste.
Hubisenior (2024) is a Portuguese tech startup which provides in-home care services for the elderly through a digital application, designed for hiring caregivers and geriatric nurses. For the right to age with dignity, Hubicare connects elders, their families, and professionals in a sustainable and qualified support network across all regions. The value proposition is based on a trusted partnership driven by the delivery of skilled and certified services by training professionals in Geriatric Care and Gerontechnology. Additionally, Hubicare's digital services are supported by data democratisation, service interoperability, and the automation of decision-making processes recurring to artificial intelligence.
BEAT Therapeutics (2024) is a biotech startup dedicated to developing first-in-class therapies for the treatment of aggressive cancers. Focused on anticancer agents that target DNA repair, the company aims to drive advances in oncology research and provide highly effective and safe therapies, that significantly impact patients' quality of life.
Cell4Food (2025) is a deep tech biotechnology startup with a B2B licensing-based business model aiming to develop cellular agriculture technologies to produce fish, molluscs and crustacean cell-based food products.
AQL Engineering (2025) specializes in the development of innovative solutions in aquaculture, marine technology, and software engineering. Our expertise includes sensor integration, real-time monitoring, and custom mobile and desktop applications to enhance operational efficiency."
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