George F. Weeden was born in 1838 and was married to Simeon's granddaughter Susan Simons; both were descendants of the royal line of Pokanoket leadership and their children made crucial contributions to the Indigenous civil rights movement in the U.S. in the early 20th Century. In 1923, their son Frederick Weeden was among the founders of the National Algonquin Indian Council and served as the first treasurer of the organization. Especially active in southern New England, the NAIC advocated for the awareness of the existence of native peoples in the broader society. Victims of prejudice and marginalization, many Pokanoket families were listed as "colored," "black," "white," or "mulatto" on census rolls, and still recalled the violent erasure of the Pokanoket legal identity from centuries before.

Perhaps the most famous modern descendent of the Pokanoket royal line was Princess Red Wing of the Seven Crescents, born Mary Glasko in Sprague, CT, in 1896. Her life and work embody great historical significance for the Pokanoket and Narragansett nations, as she was a strong advocate for the visibility of New England tribes. Founder of the Tomaquag Indian Memorial Museum, Princess Red Wing was also inducted into the Rhode Island Heritage Hall of Fame, received an honorary doctorate from the University of Rhode Island, and in 1946 she became the first Native American to address the United Nations.