The Research Laboratory of Periodontal Tissue Engineering

Scientific Articles (*corresponding author)

  • JH Lin, CC Tu, YW Chen, CY Wang, CM Liu, MY Kuo, PC Chang*. Influence of Adjacent Teeth Absence or Extraction on the Outcome of Non-Surgical Periodontal Therapy. Int J Environ Res Public Health. 2019 Nov;16(22): E4344 (SCI) [PubMed]
  • HT Luo, CH Lee, MH Chen, TC Yang, SE Huang, PC Chang*. Incidence of Ridge Height Discrepancy and Insufficient Ridge Width in the Posterior Region: A Cone-beam Computed Tomography Study. J Periodontics Impl Dent. 2019; 2(1): 35-41
  • YT Jhang, YW Chen, CY Wang, CC Tu, CM Liu, MY Kuo, PC Chang*. Association Between Initial Clinical Parameters and the Outcome of Non-Surgical Periodontal Therapy: Patient-, Tooth-, and Site-level Analyses. J Periodontics Impl Dent. 2019; 2(1): 17-24
  • CP Chiang, O Hsieh, WC Tai, YJ Chen, PC Chang*. Clinical Outcomes of Adjunctive Indocyanine Green-Diode Lasers Therapy for Treating Refractory Periodontitis: A Randomized Controlled Trial with In Vitro Assessment. J Formos Med Assoc. 2019 Aug [Accepted for publication] (SCI) [PubMed]
  • YW Chen, O Hsieh, YA Chen, LL Chiou, PC Chang*. Randomized Controlled Clinical Effectiveness of Adjunct 660-nm Light-Emitting Diode Irradiation during Non-Surgical Periodontal Therapy. J Formos Med Assoc. 2019 Jan [Accepted for publication] (SCI) [PubMed]
  • PC Chang, YW Chen, CC Tu, MY Kuo, CM Liu, CY Wang. Association of Initial Mucogingival Status with Clinical Outcome of Non-Surgical Periodontal Therapy: A Retrospective Analysis of 204 Patients. J Formos Med Assoc. 2019 May; 118(5): 932-8 (SCI) [PubMed]
  • PC Chang*, HC Chang, TC Lin, WC Tai. Preclinical Alveolar Ridge Preservation Using Small-sized Particles of Bone Replacement Graft in Combination with a Gelatin Cryogel Scaffold. J Periodontol. 2018 Oct; 89(10): 1221-9 (SCI) [PubMed]
  • YC Wu, N Lee, YK Tu, CP Huang, NT Huang, YF Chen, PC Chang*. Salivary Biomarker Combination Prediction Model for the Diagnosis of Periodontitis in A Taiwanese Population. J Formos Med Assoc. 2018 Sep; 117(9): 841-8 (SCI) [PubMed]
  • CH Lee, YW Chen, YK Tu, YC Wu, PC Chang*. The Potential of Salivary Biomarkers for Predicting the Sensitivity and Monitoring the Response to Non-Surgical Periodontal Therapy: A Preliminary Assessment. J Periodontal Res. 2018 Aug; 53(4): 545-54 (SCI) [PubMed]
  • LL Chiou, CP Chiang, PC Chang*. Effect of 810-nm Diode Laser on Reducing Dentinal Hypersensitivity After Periodontal Treatment. J Periodontics Impl Dent. 2018; 1(1): 41-7
  • JH Lin, F Fang, MC Yu, CH Wang, PC Chang*. Modulation of Periodontitis Progression Using pH-Responsive Nanosphere Encapsulating Metronidazole or N-Phenacylthialzolium Bromide. J Periodontal Res. 2018 Feb; 53(1): 22-8 (SCI) [PubMed]
  • SH Wang, CP Huang, PC Chang*. Current Treatment Considerations for Aggressive Periodontitis. J Taiwan Acad Periodontol. 2017; 22(4): 317-28
  • HC Chang, C Yang, F Feng, FH Lin, CH Wang, PC Chang*. BMP-2 Loaded Poly(D,L-Lactide-co-Glycolide) Microspheres Enhance Osteogenic Potential of Gelatin/Hydroxyapatite/Beta-Tricalcium Phosphate Cryogel Composite for Alveolar Ridge Augmentation. J Formos Med Assoc. 2017 Dec; 116(12): 973-81 (SCI) [PubMed]
  • SH Chen, HL Chan, Y Lu, SH Ong, HL Wang, EH Ko, PC Chang*. A Semi-Automatic Algorithm for Preliminarily Assessing the Thickness of Labial Gingiva and Alveolar Bone of Maxillary Anterior Teeth. Int J Oral Maxillofac Implants. 2017 Nov-Dec; 32(6): 1273-80 (SCI) [PubMed]
  • HC Chang, MY Kuo, RY Huang, PC Chang*. Distribution of Regular and Small Size Bone Replacement Graft Particles in a Gelatin Cryogel Scaffold in Support of Alveolar Bone Regeneration. J Taiwan Acad Periodontol. 2017; 22(3): 202-10
  • MH Ho, HC Chang, YC Chang, J Claudia, TC Lin, PC Chang*. PDGF-Metronidazole Encapsulated Nanofibrous Functional Layers on the Collagen Membrane Promote Alveolar Ridge Regeneration. Int J Nanomedicine. 2017 Aug; 12:5525-35 (SCI) [PubMed]
  • PC Chang*, YC Chao, MH Hsiao, HS Chou, YH Jheng, XH Yu, N Lee, C Yang, DM Liu. Inhibition of Periodontitis Induction Using a Stimuli-Responsive Hydrogel Carrying Naringin. J Periodontol. 2017 Feb; 88(2): 190-6 (SCI) [PubMed]
  • CY Tao, N Lee, HC Chang, C Yang, XH Yu, PC Chang*. Evaluation of 660 nm LED Light Irradiation on the Strategies for Treating Experimental Periodontal Intrabony Defects. Lasers Med Sci. 2016 Aug. 31(6): 1113-21 (SCI) [PubMed]
  • MC Yu, CY Chang, YC Chao, YH Jheng, C Yang, N Lee, SH Yu, XH Yu, DM Liu, PC Chang*. pH-Responsive Hydrogel with an Anti-Glycation Agent for Modulating Experimental Periodontitis. J Periodontol. 2016 Jun; 87(6): 742-8 (SCI) [PubMed]
  • SC Tsai, YH Jheng, CY Wang, YW Chen, YF Lin, CC Chen, PC Chang*. Osseous wound repair under inhibition of the axis of advanced glycation end-products and the advanced glycation end-products receptor. J Formos Med Assoc. 2015 Oct; 114(10): 973-80 (SCI) [PubMed]
  • YC Chao, PC Chang, JH Fu, HL Wang, HL Chan. Surgical Site Assessment and Soft Tissue Management for Bone Augmentation. Int J Periodontics Restorative Dent 2015 Sep-Oct; 35(5): e75-83 (SCI) [PubMed]
  • CY Wang, SC Tsai, MC Yu, YF Lin, CC Chen, PC Chang*. Light-Emitting Diode Irradiation Promotes Donor Site Wound Healing of the Free Gingival Graft. J Periodontol. 2015 May; 86(5): 674-81 (SCI) [PubMed]
  • PC Chang*, CY Wang, LY Chong. Controlling periodontal bone levels with multiple LED irradiations. Lasers Med Sci. 2015 Feb; 30(2): 741-6 (SCI) [PubMed]
  • PC Chang*, Lee CT, Zhang Z, Kok F, Lin D, Lee P, Ngo R. The Preferred Anterior Crown-Mucogingival Profile of Young People of Chinese Ethnicity in Singapore. J Taiwan Acad Periodontol. 2015; 20(1): 3-14
  • SH Yu, HL Chan, LY Chong, YH Jheng, PC Chang*. Evaluation of the Osteogenic Potential of Growth Factor-Rich Demineralized Bone Matrix In Vivo. J Periodontol. 2015 Jan. 86(1): 36-43 (SCI) [PubMed]
  • PC Chang*, CY Wang, SC Tsai. Combination of LED Light and Platelet-Derived Growth Factor to Accelerate Dentoalveolar Osteogenesis. J Clin Periodontol. 2014 Oct; 41(10): 999-1006 (SCI) [PubMed]
  • PC Chang*, SC Tsai, LY Chong, MJ Kao. N-Phenacylthiazolium Bromide Inhibits the AGE-RAGE Axis to Modulate Experimental Periodontitis in Rats. J Periodontol. 2014 Jul;85(7):e268-276 (SCI) [PubMed]
  • PC Chang*, LY Chong, SC Tsai, LP Lim. Aminoguanidine Inhibits the Age-Rage Axis to Modulate the Induction of Periodontitis but has Limited Effects on the Progression and Recovery of Experimental Periodontitis: A Preliminary Study. J Periodontol. 2014 May;85(5):729-739 (SCI) [PubMed]
  • PC Chang*, SC Tsai, YH Jheng, YF Lin, CC Chen. Soft tissue wound healing by anti-advanced glycation end products agents. J Dent Res. 2014 Apr 93(4):383-93 (SCI) [PubMed]
  • PC Chang*, LY Chong, A Dovban, LP Lim, J Lim, YP Kuo, CH Wang. Sequential PDGF-Simvastatin Release Promotes Dentoalveolar Regeneration. Tissue Eng Part A. 2014 Jan;20(1-2): 356-64. (SCI) [PubMed]
  • PC Chang*, A Dovban, LP Lim, LY Chong, MY Kuo, CH Wang. Dual Delivery of PDGF and Simvastatin to Accelerate Periodontal Regeneration In Vivo. Biomaterials. 2013 Dec;34(38):9990-9. (SCI) [PubMed]
  • PC Chang*, LY Chien, LY Chong, YP Kuo, Hsiao JK. Glycated matrix up-regulates inflammatory signaling similarly to Porphyromonas gingivalis lipopolysaccharide. J Periodontal Res. 2013 Apr;48(2):184-93. (SCI) [PubMed]
  • PC Chang*, LY Chien, Ye Y, MJ Kao. Irradiation by light-emitting diode light as an adjunct to facilitate healing of experimental periodontitis in vivo. J Periodontal Res. 2013 Apr;48(2):135-43. (SCI) [PubMed]
  • PC Chang*, LY Chien, JF Yeo, YP Wang, MC Chung, LY Chong, MY Kuo, CH Chen, HC Chiang, BN Ng, QQ Lee, YK Phay, JR Ng, KY Erk. Progression of periodontal destruction and the roles of advanced glycation end products in experimental diabetes. J Periodontol. 2013 Mar;84(3):379-88. (SCI) [PubMed]
  • LY Chong, LY Chien, MC Chung, Liang K, J LimC, JH Fu, CH Wang, PC Chang*. Controlling the proliferation and differentiation stages to initiate periodontal regeneration. Connect Tissue Res. 2013;54(2):101-7. (SCI) [PubMed]
  • PC Chang*, K Liang, J Lim, MC Chung, LY Chien. A comparison of the thresholding strategies of micro-CT for periodontal bone loss: a pilot study. Dentomaxillofac Radiol. 2013;42(2):66925194. (SCI) [PubMed]
  • PC Chang*, YJ Seol, SA Goldstein, WV Giannobile. Determination of the dynamics of healing at the tissue-implant interface by means of microcomputed tomography and functional apparent moduli. Int J Oral Maxillofac Implants. 2013 Jan-Feb;28(1):68-76. (SCI) [PubMed]
  • PC Chang*, MC Chung, C Lei, LY Chong, CH Wang. Biocompatibility of PDGF-simvastatin double-walled PLGA (PDLLA) microspheres for dentoalveolar regeneration: a preliminary study. J Biomed Mater Res A. 2012 Nov;100(11):2970-8. (SCI) [PubMed]
  • PC Chang*, WV Giannobile. Functional assessment of dental implant osseointegration. Int J Periodontics Restorative Dent. 2012 Oct;32(5):e147-53. (SCI) [PubMed]
  • PC Chang*, LP Lim. Interrelationships of periodontitis and diabetes: A review of the current literature. J Dent Sci. 2012 Sep;7(3):272-82. (SCI)
  • PC Chang*, LP Lim, LY Chong, AS Dovban, LY Chien, MC Chung, C Lei, MJ Kao, CH Chen, HC Chiang, YP Kuo, CH Wang. PDGF-simvastatin delivery stimulates osteogenesis in heat-induced osteonecrosis. J Dent Res. 2012 Jun;91(6):618-24. (SCI) [PubMed]
  • PC Chang*, MC Chung, YP Wang, LY Chien, J LimC, K Liang, LY Chong, YP Kuo, CH Chen, HC Chiang. Patterns of diabetic periodontal wound repair: a study using micro-computed tomography and immunohistochemistry. J Periodontol. 2012 May;83(5):644-52. (SCI) [PubMed]