1. Chia-Wei Liu, Yi-Mei Wang, Shun-Ying Chen, Liang-Yin Lu, Ting-Yu Liang, Ke-Chu Fang, Peng Chen, I-Chen Lee, Wen-Chuan Liu, Ami Kumar, Sheng-Han Kuo, Jye-Chang Lee, Chung-Chuan Lo, Shun-Chi Wu, Ming-Kai Pan*. The cerebellum shapes motions by encoding motor frequencies with precision and cross-individual uniformity. Nature Biomedical Engineering, 2025 May 27. DOI: 10.1038/s41551-025-01409-5. (IF: 27.7)
2. Chih-Chun Lin, Ke-Chu Fang, Ilaria Balbo, Ting-Yu Liang, Chia-Wei Liu, Wen-Chuan Liu, Yi-Mei Wang, Yen-Ling Hung, Kai-Chien Yang, Scott Kun Geng, Chun-Lun Ni, Christopher P. Driscoll, David S. Ruff, Ami Kumar, Nadia Amokrane, Natasha Desai, Phyllis L. Faust, Elan D. Louis, Sheng-Han Kuo*, Ming-Kai Pan*. Reduced cerebellar rhythm by climbing fiber denervation is linked to motor rhythm deficits in mice and ataxia severity in patients. Science Translational Medicine. 2025 Feb 26;17(787):eadk3922. (Featured article) (IF: 15.8)
3. Ming-Kai Pan*. Targeting the fundamentals for tremors: the frequency and amplitude coding in essential tremor. Journal of Biomedical Science. 2025 Feb 10;32(1):18 (Invited review)
4. Yi-Mei Wang, Chia-Wei Liu, Shun-Ying Chen, Liang-Yin Lu, Wen-Chuan Liu, Jia-Huei Wang, Chun-Lun Ni, Shi-Bing Wong, Ami Kumar, Jye-Chang Lee, Sheng-Han Kuo, Ming-Kai Pan*. Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients. Science Translational Medicine. 2024 May 15;16(747):eadl1408 (IF: 15.8)
5. Yin-Tzu Hsieh, Kai-Chun Jhan, Jye-Chang Lee, Guan-Jie Huang, Chang-Ling Chung, Wun-Ci Chen, Ting-Chen Chang, Bi-Chang Chen, Ming-Kai Pan*, Shun-Chi Wu*, Shi-Wei Chu* (Co-corresponding) TAG-SPARK: Empowering High-Speed Volumetric Imaging with Deep Learning and Spatial Redundancy. Advanced Science 2024, Sep 16:e2405293. (IF: 14.3)
6. Pan M-K*, Li Y-S, Wang S-B, Ni C-L, Wang Y-M, Liu W-C, Lu L-Y, Lee J-C, Cortes EP, Vonsattel J-P, Sun Q, Louis E, Faust P, Kuo S-H*. Cerebellar oscillations driven by synaptic pruning deficits of cerebellar climbing fibers contribute to tremor pathophysiology. Science Translational Medicine. 2020 Jan 15;12(526):eeey1769 (Featured article) (IF: 17.9)
7. Chun-Lun Ni, Yi-Ting Lin, Liang-Yin Lu, Jia-Huei Wang, Wen-Chuan Liu, Sheng-Han Kuo, Ming-Kai Pan* Tracking motion kinematics and tremor with intrinsic oscillatory property of instrumental mechanics. Bioengineering & Translational Medicine. 2022. Oct 22;8(2):e10432, eCollection 2023 Mar (IF: 10.7).
1. Yi-Mei Wang, Ming-Kai Pan*, Wei-Lieh Huang*. Sex differences in the association between error-related negativity and harm avoidance during emotional Stroop task. J Formos Med Assoc. 2025 Apr 7:S0929-6646(25)00146-9. doi: 10.1016/j.jfma.2025.03.028.
2. Ami Kumar, Yi-Mei Wang, Ming-Kai Pan*, Sheng-Han Kuo*. Protocol for recording physiological signals from the human cerebellum using electroencephalography. STAR protocols (Co-corresponding author & lead contact). 2025 Jan 26;6(1):103601.
3. Ami Kumar, Chih-Chun Lin, Sheng-Han Kuo & Ming-Kai Pan*. Physiological recordings of the cerebellum in movement disorders. Cerebellum 2023 Oct;22(5):985-1001.
4. Lillian G. Matthews, Corey B. Puryear, Susana S. Correia, Sharan Srinivasan, Gabriel M. Belfort, Ming-Kai Pan*, Sheng-Han Kuo*. T-type calcium channels as therapeutic targets in essential tremor and Parkinson's disease. Annuals of Clinical and Translational Neurology 2023 Apr;10(4):462-483.
5. Ming-Kai Pan* and Sheng-Han Kuo. Essential tremor: Clinical perspectives and pathophysiology. Journal of the Neurological Sciences 2022. Apr 15;435:120198 (Invited review)
6. S-B Wong, Y-M Wong, C-C Lin, Scott Kun Geng, Nora Vanegas-Arroyave, Seth L. Pullman, S-H Kuo, M-K Pan*. Cerebellar Oscillations in Familial and Sporadic Essential Tremor. Cerebellum. 2021 Jun 21(3):425-431
7. Pan M-K, Ni C-L, Wu Y-C, Li Y-S, Kuo S-H*. Animal Models of Tremor: Relevance to Human Tremor Disorders. Tremor Other Hyperkinetic Movements (N Y). 2018 Oct 9;8:587
8. Pan M-K*, Kuo S-H*. Tracking the central and peripheral origin of tremor. Clinical Neurophysiology. 2018 Jul;129(7):1451-1452. (IF: 3.866)
9. Pan M-K, Kuo S-H, Tai C-H, Liou J-Y, Pei J-C, Chang C-Y, Wang Y-M, Lui W-C, Wang T-R, Lai W-C, Kuo C-C*. Neuronal firing patterns outweigh circuitry oscillations in parkinsonian motor control. Journal of Clinical Investigation. 2016 Dec 1;126(12):4516-4526 (IF:14.808)
10. Pan M-K, Tai C-H, Liu W-C, Pei J-C, Lai W-C, Kuo C-C*. Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficits. Journal of Clinical Investigation. 2014;124(10):4629-4641 (IF: 14.808)
11. Pan M-K, Huang S-C, Lo Y-C, Yang C-C, Cheng T-W, Yang C-C, Hua M-S, Lee M-J*, and Tseng W-YI*. Microstructural integrity of cerebral fiber tracts in hereditary spastic paraparesis with SPG11 mutation. American Journal of Neuroradiology (AJNR). 2013;34(5):990-996, S991. (IF: 3.825)
12. Pan M-K, Tai C-H, and Kuo C-C*. [Parkinson's disease and cortico-Basal Ganglia circuits]. Acta Neurol Taiwan. 2010;19(3):213-222.
13. Regina T Martuscello, Meng-Ling Chen, Steven Reiken, Leah R Sittenfeld, David S Ruff, Chun-Lun Ni, Chih-Chun Lin, Ming-Kai Pan, Elan D Louis, Andrew R Marks, Sheng-Han Kuo, Phyllis L Faust. Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium 'leak' in tremor pathophysiology. Acta Neuropathologica (2023) 146, 301-318
14. Chang-Ling Chung, Tommaso Furieri, Jyun-Yi Lin, Ting-Chen Chang, Jye-Chang Lee, Yi-Fan Chen, Ming-Kai Pan, Stefano Bonora, Shi-Wei Chu. Plug-and-play adaptive optics for two photon high-speed volumetric imaging. JPhys Photonics 2022 May 4(2): 024003
15. Sheng-Han Kuo, Inmaculada Tasset, Melody M. Cheng, Antonio Diaz, Ming-Kai Pan, Ori J. Lieberman, Samantha J. Hutten, Roy N. Alcalay, Sangjun Kim, Pilar Ximénez-Embún, Li Fan, Donghoon Kim, Han Seok Ko, Talene Yacoubian, Ellen Kanter, Ling Liu, Guomei Tang, Ling Javier Muñoz, Sergio Pablo Sardi, Aiqun Li, Li Gan, Ana Maria Cuervo*, David Sulzer* Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy Science Advances 2022. 8(6): eabm6393 (IF: 14.136)
16. Yueh-Chi Wu, Elan D Louis, John Gionco, Ming-Kai Pan, Phyllis L Faust, Sheng-Han Kuo. Increased Climbing Fiber Lateral Crossings on Purkinje Cell Dendrites in the Cerebellar Hemisphere in Essential Tremor. Movement Disorders 2021. Jun;36(6):1440-1445 (IF: 10.338)
17. Nadia Amokrane, Anisha Viswanathan, Samantha Freedman, Chen-Ya Yang, Natasha A. Desai, Ming-Kai Pan, Sheng-Han Kuo, MD, Chi-Ying Lin. Impulsivity in Cerebellar Ataxias: Testing the Cerebellar Reward Hypothesis in Humans. Movement Disorders 2020 Aug 35(8): 1491-1493 (IF: 10.338)
18. Chun-Hwei Tai, Ming-Kai Pan, Sheng-Hong Tseng, Tien-Rei Wang, Chung-Chin Kuo. Hyperpolarization of the Subthalamic Nucleus Alleviates Hyperkinetic Movement Disorders. Scientific Reports. 2020 May 19;10(1):8278 (IF: 4.380).
19. Yueh-Feng Wu, Rai-Teng Ye, Ming-Kai Pan, Sung-Jan Lin, Hsin-Yuan Tan. A Custom Multiphoton Microscopy Platform for Live Imaging of Mouse Cornea and Conjunctiva. JoVE-Journal of Visualized Experiments 2020 May 17;(159).
20. Kuo SH, Louis ED, Faust PL, Handforth A, Chang SY, Avlar B, Lang EJ, Pan MK, Miterko LN, Brown AM, Sillitoe RV, Anderson CJ, Pulst SM, Gallagher MJ, Lyman KA, Chetkovich DM, Clark LN, Tio M, Tan EK, Elble RJ. Current Opinions and Consensus for Studying Tremor in Animal Models. Cerebellum. 2019 Dec;18(6):1036-1063. (IF: 3.847)
21. Fan SM, Chang YT, Chen CL, Wang WH, Pan MK, Chen WP, Huang WY, Xu Z, Huang HE, Chen T, Plikus MV, Chen SK, Lin SJ. External light activates hair follicle stem cells through eyes via an ipRGC-SCN-sympathetic neural pathway. Proc Natl Acad Sci U S A (PNAS). 2018 Jun; 115(29): E6880-E6889. (IF: 11.205)
22. S-H Kuo, C-Y Lin, Jie Wang, Peter A Sims; M-K Pan, J-You Liou, Danielle Lee; William J Tate, Geoffrey C Kelly, Elan D Louis, Phyllis L Faust. Climbing fiber-Purkinje Cell Synaptic Pathology in Tremor and Cerebellar Degenerative Diseases. Acta Neuropathologica. 2017 Jan;133(1):121-138 (IF:17.088)
23. Louis ED, Kuo SH, Wang J, Tate WJ, Pan MK, Kelly GC, Gutierrez J, Cortes EP, Vonsattel JG, Faust PL. Cerebellar Pathology in Familial vs. Sporadic Essential Tremor. Cerebellum 2017 Aug;16(4):786-791 (IF: 3.847)
24. Kuo SH, Wang J, Tate WJ, Pan MK, Kelly GC, Gutierrez J, Cortes EP, Vonsattel JG, Louis ED, Faust PL. Cerebellar pathology in early and late onset essential tremor. Cerebellum 2017 Apr;16(2):473-482 (IF: 3.847)
25. Kuo S-H, Lin C-Y, Wang J, Liou J-Y, Pan M-K, Louis R, Wu W-P, Gutierrez J, Louis E, Faust P. Deep Brain Stimulation and Climbing Fiber Synaptic Pathology in Essential Tremor. Ann Neurol. 2016 Sep;80(3):461-5 (IF: 10.422)
26. Yang Y-C, Tai C-H, Pan M-K, and Kuo C-C. The T-type calcium channel as a new therapeutic target for Parkinson's disease. Pflugers Archiv : European journal of physiology. 2014;466(4):747-755. (IF: 4.101)
27. Shen C-P, Liu S-T, Zhou W-Z, Lin F-S, Lam AY-Y, Sung H-Y, Chen W, Lin J-W, Chiu M-J, Pan M-K, Kao J-H, Wu J-M, and Lai F. A physiology-based seizure detection system for multichannel EEG. PLoS ONE. 2013;8(6):e65862. (IF: 3.534)
28. Tai C-H, Pan M-K, Lin JJ, Huang C-S, Yang Y-C, and Kuo C-C. Subthalamic discharges as a causal determinant of parkinsonian motor deficits. Ann Neurol. 2012;72(3):464-476. (IF: 11.193)
29. Tai C-H, Yang Y-C, Pan M-K, Huang C-S, and Kuo C-C. Modulation of subthalamic T-type Ca2+ channels remedies locomotor deficits in a rat model of Parkinson disease. Journal of Clinical Investigation. 2011;121(8):3289-3305. (IF: 14.808)
30. Tai C-H, Wu R-M, Lin C-H, Pan M-K, Chen Y-F, Liu H-M, Lu H-H, Tsai C-W, and Tseng S-H. Deep brain stimulation therapy for Parkinson's disease using frameless stereotaxy: comparison with frame-based surgery. European Journal of Neurology. 2010;17(11):1377-1385. (IF: 6.089)
31. Lee M-J, Cheng T-W, Hua M-S, Pan M-K, Wang J, Stephenson DA, and Yang C-C. Mutations of the SPG11 gene in patients with autosomal recessive spastic paraparesis and thin corpus callosum. J Neurol Neurosurg Psychiatr. 2008;79(5):607-609. (IF: 7.349)
32. Chao C-C, Yang C-C, Hsiao C-H, Pan M-K, Lin C-H, and Hsieh S-T. Nephrogenic systemic fibrosis associated with gadolinium use. J Formos Med Assoc. 2008;107(3):270-274.