Publications List

Cheng-Hsun Hsu, Hsin-Yu Yu, Ho Jun Lee, Pei-Hao Wu, Shing-Jong Huang, Jong Suk Lee*, Tsyr-Yan Yu*, Yi-Pei Li*, Dun-Yen Kang*, "Fast Water Transport in UTSA-280 via a Knock-off Mechanism." Angew. Chem.Int. Ed.2023, 62, e202309874. 

Fang-Hsuan Hu, Li-Tang Chi, Guan-Bo Syu, Tsyr-Yan Yu, Ming-Pei Lin, Jiun-Jen Chen, Wen-Yueh Yu, Dun-Yen Kang, "Mixed-linker MOF-303 membranes for pervaporation". Journal of Membrane Science Letters, 3, 100053 (2023).

Tseng, H.C., Pan, C.P, “Dopamine Activates the D1R‑Zn2+ Signaling Pathway to Trigger Inflammatory Response in Primary‑Cultured Rat Embryonic Cortical Neurons” Cell. Mol. Neurobiol. (2023) 43, 3593–3604

Magoling, B., Chen,Y., Wu, A.Y., Wong, W.W., Chou, S.T., Huang, H., Sung, Y., Hsieh, H., Huang, P., Lee, K., Huang, K., Chen,R., Chen,Y., Lai, C.P. “Membrane Protein Modification Modulates Big and Small Extracellular Vesicle Biodistribution and Tumorigenic Potential in Breast Cancers In Vivo.” Adv. Mater. (2023), 35, 2208966.

Yi-Rui Zhong, Tsyr-Yan Yu*, Li-Kang Chu*,“Roles of functional lipids in bacteriorhodopsin photocycle in various delipidated purple membranes”. Biophysical Journal, 121(10), 1789-1798 (2022)

Cheng-Chieh Lin , Shing-Jong Huang , Pei-Hao Wu , Tzu-Pei Chen , Chih-Ying Huang , Ying-Chiao Wang , Po-Tuan Chen , Denitsa Radeva , Ognyan Petrov , Vladimir Gelev , Raman Sankar , Chia-Chun Chen , Chun-Wei Chen*, Tsyr-Yan Yu*, “Direct Investigation of the Reorientational Dynamics of A-site Cations in 2D Organic-Inorganic Hybrid Perovskite by Solid-State NMR”. Nature Communications, 13, 1513 (2022).

Lin, S.H., Tsai, G.Y., Wang, M.J.,*, Chen, S.Y. *, “Effects of Cancer Cell-Derived Nanovesicle Vaccines Produced by the Oxidative Stress-Induced Expression of DAMP and Spontaneous Release/Filter Extrusion in the Interplay of Cancer Cells and Macrophages” Biomedicines (2022), 10, 1977

Hsiao, Y.T., Tsai, C.N., Chen, T.H., Hsieh, C.L*, “Label-free dynamic imaging of chromatin in live cell nuclei by high-speed scattering-based interference microscopy” ACS Nano 16(2), 2774–2788 (2022)

Lee, C.W., Hsu, L.F., Wu, I.L., Wang, Y.L., Chen, W.C., Liu, Y.J., Yang, L.T., Tan, C.L,, Luo, Y.H., Wang, C.C., Chiu, H.W., Yang, T.C., Lin, Y.Y., Chang, H.A., Chiang, Y.C., Chen, C.H., Lee, M.H., Peng, K.T., Huang, C.C.,*” Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice”. J. Hazard. Mater. (2022) 430, 128431

Muneekaew, S., Wang, M.J.,* Chen, S.Y.*,” Control of stem cell differentiation by using extrinsic photobiomodulation in conjunction with cell adhesion pattern”. Sci. Rep. (2022) 12, 1812

C-H Liu, S-J Huang*, Tsyr-Yan Yu*, “Cholesterol Modulates the Interaction between HIV-1 Viral Protein R and Membrane”. Membranes, 11(10), 784 (2021).

Cheng, C.Y., Liao, Y.H., Hsieh, C.L.*, “Dynamic signal of live biological cells under interferometric scattering (iSCAT) microscopy and its impacts on single-particle tracking” J. Phys. D: Appl. Phys. 54, 364001 (2021)

Chien, J.C., *Badr, C.E., *Lai, C.P. (2021). “Multiplexed bioluminescence-mediated tracking of DNA double strand break repairs in vitro and in vivo”. Nat. Protoc. Vol.16 (8) 3933-3953

Liao, C. C. Chen, Y. Z. Lin, S. J. Cheng, H. W. Wang, J. K. Wang, Y. L. Han, Y. Y. *Huang, N. T.(2021) “A microfluidic microwell device operated by the automated microfluidic control system for surface-enhanced Raman scattering-based antimicrobial susceptibility testing” Biosens. Bioelectron. 191, 113483

PB Zhong, C-H Liu, Y-T Chen*, T-Y Yu*, “The Study of HIV-1 Vpr-Membrane and Vpr-hVDAC-1 Interactions by Graphene Field-Effect Transistor Biosensors”. ACS. Appl. Bio. Mater., 3(9), 6351-6357 (2020).

R Ibrahim, S-Y Yeh, K-P Lin, F Ricardo, T-Y Yu, C-C Chan, J-W Tsai*, Y-T Liu*, “Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration”. Cell. Mol. Life Sci., 77(7), 1421-1434 (2020).

Y.-Y. Liu, B.-M. Chang, and H.-C. Chang*, “Nanodiamond-enabled biomedical imaging,” Nanomedicine 15, 1599–1616 (2020).

Y. Y. Hui, O. Y. Chen, H.-C. Chang, and *M.-C. Su, “Diamond nanothermometry,” in 21st Century Nanoscience – A Handbook: Exotic Nanostructures and Quantum Systems (Volume Five), ed. K. D. Sattler (CRC Press, 2020), Chap. 26, 26-1–26-18.2019

Wu, A.Y., Sung, Y., Chen, Y., Chou, S.T., Guo, V., Chien, J.C., Ko, J.J., Yang, A.L., Huang, H., Chuang, J., Wu, S., Ho, M., Ericsson, M., Lin, W., Cheung, C.H.Y., Juan, H., Ueda, K., Chen, Y., *Lai, C.P. (2020). “Multiresolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism”. Adv. Sci. 7, 2001467

Chien, J.C., Tabet, E., Pinkham, K., da Hora, C.C., Chang, J.C., Lin, S., *Badr, C.E., *Lai, C.P. (2020). A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo. Nucleic Acids Res, Vol48 (17), e100

Yan-Ting Chuang,; Sheng-Ding Chen,; Wei-Chun Huang,; Tien-Lin Shen,; Ming-Shien Chang,; Yang-Fang Chen,; Ya-Ping Hsieh*,; Yuan-Huei Chang*,; and Mario Hofmann*., Multilevel Optical Labeling by Spectral Luminescence Control in Nanodiamond Color Centers. ACS Appl. Mater. Interfaces 2020, 12, 43, 49006–49011

Huang, H. K., Cheng, H. W., Liao, C. C., Lin, S. J., Chen, Y. Z., Wang, J. K., Wang, Y. L., Huang, N. T. (2020) ” Bacteria encapsulation and rapid antibiotic susceptibility test using a microfluidic microwell device integrating surface-enhanced Raman scattering” Vol. 20 (14) 2520-2528

Y-T Liu, Y-J Yen, F Ricardo, Y Chang, P-H Wu, S-J Huang, K-P Lin*, T-Y Yu*, “Biophysical characterization and modulation of Transthyretin Ala97Ser”. Ann. Clin. Transl. Neur., 6(10), 1961-1970(2019).

Y-M Kao, C-H Cheng, M-L Syue, H-Y Huang, I-C Chen*, T-Y Yu*, L-K Chu*, “Photochemistry of Bacteriorhodopsin with Various Oligomeric Statuses in Controlled Membrane Mimicking Environments: A Spectroscopic Study from Femtoseconds to Milliseconds.” J. Phys. Chem. B, 123(9), 2032-2039 (2019).

H. Y. Huang, M. L. Syue, I. C. Chen, T. Y. Yu, L. K. Chu, “Influence of Lipid Compositions in the Events of Retinal Schiff Base of Bacteriorhodopsin Embedded in Covalently Circularized Nanodiscs: Thermal Isomerization, Photoisomerization, and Deprotonation”. J. Phys. Chem. B, 123(43), 9123-9133 (2019).

M. T. Eddy, T. Y. Yu, G. Wagner, R. G. Griffin*, “Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR”. J. Biomol. NMR, 73(8-9), 451-460 (2019).

S.-J. Kuo, S.-W. Chang, Y. Y. Hui, O. Y. Chen, Y.-W. Chen, C.-C. Lin, D. Wan, H.-L. Chen*, and H.-C. Chang*, “Fluorescent microdiamonds conjugated with hollow gold nanoparticles as photothermal fiducial markers in tissue,” J. Mater. Chem. C 7, 15197−15207 (2019).

L.-J. Su, H.-H. Lin, M.-H. Wu, L. Pan, K. Yadav, H.-H. Hsu, T.-Y. Ling, Y.-T. Chen, and H.-C. Chang*, “Intracellular delivery of luciferase with fluorescent nanodiamonds for dual-modality imaging of human stem cells,” Bioconjugate Chem. 30, 2228−2237 (2019).

Y. Y. Hui, O. Y. Chen, T. Azuma, B.-M. Chang, F.-J. Hsieh, and H.-C. Chang*, “All-optical thermometry with nitrogen-vacancy centers in nanodiamond-embedded polymer films,” J. Phys. Chem. C 123, 15366−15374 (2019).

F.-J. Hsieh, S. Sotoma, H.-H. Lin, C.-Y. Cheng, T.-Y. Yu, C.-L. Hsieh, C.-H. Lin*, and H.-C. Chang*, “Bioorthogonal fluorescent nanodiamonds for continuous long-term imaging and tracking of membrane proteins,” ACS Appl. Mater. Interfaces 11, 19774–19781 (2019).

F.-J. Hsieh, Y.-W. Chen, Y. Y. Hui, C.-H. Lin, and H.-C. Chang*, “Quantification and imaging of antigens on cell surface with lipid-encapsulated fluorescent nanodiamonds,” Micromachines 10, 304 (2019) (10pp).

W. W.-W. Hsiao*, H.-H. Lin, and H.-C. Chang*, “Diamond nanoparticles for drug delivery and monitoring,” in Carbon-Based Nanosensor Technology, Springer Series on Chemical Sensors and Biosensors, ed. C. Kranz (Springer, 2019), 17: 119–140.

Khouj, E.M., Prosser, S.L., Tada, H., Chong, W.M., Liao, J.-C., Sugasawa, K., Morrison, C.G.* (2019) Differential requirements for the EF-hand domains of human centrin 2 in primary ciliogenesis and nucleotide excision repair. Journal of Cell Science, 132(19), jcs228486.

Lo, C.-H., Lin, I.-H., Yang, T.T., Huang, Y.-C., Tanos, B.E., Chou, P.-C., Chang, C.-W., Tsay, Y.-G., Liao, J.-C., Wang, W.-J.* (2019)  Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation. Journal of Cell Biology, 218(10), 3489-3505.

Pan, T.-C., Chieh Wen, L., Chong, W.M., Tsai, C.-N., Lee, K.-Y., Chen, P.-Y., Liao, J.-C., Yu, M.-J.* (2019) Differential proteomics reveals discrete functions of proteins interacting with hypo- vs. hyper-phosphorylated NS5A of the hepatitis C virus. Journal of Proteome Research, 18 (7), 2813-2825.

Yang, T.T., Tran T.M.N., Chong, W.M., Huang, C.-E., Liao, J.-C.* (2019) Single particle tracking localization microscopy reveals nonaxonemal dynamics of intraflagellar transport proteins at the base of mammalian primary cilia. Molecular Biology of the Cell, 30, 828-837.

Chu, S.-H., Lo, L.-L., Lai, R.L., Yang, T.T., Liao, J.-C., Huang, N.-T.* (2019) A microfluidic device for in situ fixation and super-resolved mechanosensation studies of primary cilia. Biomicrofluidics, 13, 014105.

Chen, C.-W., Wang, H.-L., Huang, C.-W., Tu, I.-C., Koorapati, A., Hsieh, S.-T., Kan, H.-W., Liao, J.-C., Chong, W. M., Naroditzky, I., Kidron, D., Eran, A., Nijim, Y., Sela, E., Feldman, H.B., Kalfon, L, Raveh-Barak, H, Falik-Zaccai, T., Elpeleg, O., Mandel, H.*, Chang, Z.-F.* (2019) Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder. Proceedings of the National Academy of Sciences, USA, 116 (2), 566-574.

Y Yusuf, J Massiot, Y-T Chang, P-H Wu, V Yeh, P-C Kuo, J Shiue*, T-Y Yu*, “Optimization of the Production of Covalently Circularized Nanodiscs and Their Characterization in Physiological Conditions”. Langmuir, 34(11), 3525-3532 (2018).

V Yeh, T-Y Lee, C-W Chen, P-C Kuo, J Shiue, L-K Chu,* and T-Y Yu*, “Highly Efficient Transfer of 7TM Membrane Protein from Native Membrane to Covalently Circularized Nanodisc”. Sci. Rep., 8, 13501 (2018).

O Shih, Y-Q Yeh, K-F Liao, C-J Su, P-H Wu, R Heenan, T-Y Yu*, and U-S Jeng*, “Membrane Charging and Swelling upon Calcium Adsorption as Revealed by Phospholipid Nanodiscs.” J. Phys. Chem. Lett., 9(15), 4287-4293 (2018).

Shown, S Samireddi, Y-C Chang, R Putikam, P-H Chang, A Sabbah, F-Y Fu, W-F Chen, C-I Wu, T-Y Yu, P-W Chung, M C Lin, L-C Chen* and K-H Chen*, “Carbon-doped SnS2 nanostructure as a high-efficiency solar fuel catalyst under visible light”. Nat. Commun., 9, 169 (2018).

Tseng TY, Chen WW, Chu IT, Wang CL, Chang CC, Lin MC, et al. The G-quadruplex fluorescent probe 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide as a biosensor for human cancers. Scientific reports. 2018;8(1):16082.

Sotoma, S.; Hsieh, F. J.; Chang, H. C., Biohybrid fluorescent nanodiamonds as dual-contrast markers for light and electron microscopies. J Chin Chem Soc-Taip 2018, 65 (9), 1136-1146.

Sotoma, S.; Hsieh, F. J.; Chang, H. C., Single-Step Metal-Free Grafting of Cationic Polymer Brushes on Fluorescent Nanodiamonds. Materials 2018, 11 (8)

Sotoma, S.; Hsieh, F. J.; Chen, Y. W.; Tsai, P. C.; Chang, H. C., Highly stable lipid-encapsulation of fluorescent nanodiamonds for bioimaging applications. Chem Commun (Camb) 2018, 54 (8), 1000-1003.

Hsieh, F. J.; Chen, Y. W.; Huang, Y. K.; Lee, H. M.; Lin, C. H.; Chang, H. C., Correlative Light-Electron Microscopy of Lipid-Encapsulated Fluorescent Nanodiamonds for Nanometric Localization of Cell Surface Antigens. Analytical Chemistry 2018, 90 (3), 1566-1571

Sotoma, S.; Epperla, C. P.; Chang, H. C., Diamond Nanothermometry. Chemnanomat 2018, 4 (1), 15-27

Sotoma, S.; Hsieh, F. J.; Chen, Y. W.; Chen, J.; Wardhani, K.; Tsai, P. C.; Chang, H. C., “Characterization and applications of fluorescent nanodiamonds surface-coated with photo-crosslinked lipids,” Proc. SPIE 2018, 10547, 1054704 (8pp).

Kuo, C. J.; Chiang, H. C.; Tseng, C. A.; Chang, C. F.; Ulaganathan, R. K.; Ling, T. T.; Chang, Y. J.; Chen, C. C.; Chen, Y. R.; Chen, Y. T., Lipid-Modified Graphene-Transistor Biosensor for Monitoring Amyloid-beta Aggregation. Acs Appl Mater Inter 2018, 10 (15), 12311-12316.

Tsai, P. C.; Epperla, C. P.; Huang, J. S.; Chen, O. Y.; Wu, C. C.; Chang, H. C., Measuring Nanoscale Thermostability of Cell Membranes with Single Gold-Diamond Nanohybrids. Angew Chem Int Edit 2017, 56 (11), 3025-3030.

V Yeh, Y Hsin, T-Y Lee, J C C Chan, T-Y Yu*, and L-K Chu*, “Lipids influence the proton pump activity of photosynthetic protein embedded in nanodiscs”. Rsc. Adv., 6(91), 88300-88305 (2016).

A Viegas, T Viennet, T-Y Yu, F Schumann, W Bermel, G Wagner, M Etzkorn*, “UTOPIA NMR: activating unexploited magnetization using interleaved low-gamma detection”. J Biomol NMR, 64(1), 9-15 (2016).

Chen, W. W., Yi, Y. H., Chien, C. H., Hsiung, K. C., Ma, T. H., Lin, Y. C., Lo, S. J., Chang, T. C. (2016) Specific polyunsaturated fatty acids modulate lipid delivery and oocyte development in C. elegans revealed by molecular-selective label-free imaging. Sci Rep. 2016 Aug 18;6:32021.

Wang, Z. F., Li, M. H., Chen, W. W., Hsu, S. T., Chang, T. C. (2016) A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes. Nucleic Acids Res. 2016 May 5;44(8):3958-68.

Epperla, C. P., Chen, O. Y., and Chang, H. C., (2016) Gold/diamond nanohybrids may reveal how hyperlocalized hyperthermia kills cancer cells. Nanomedicine (Lond). 11(5), 443-5.

T-Y Lee, V Yeh, J Chuang, J C C Chan, L-K Chu*, T-Y Yu*, “Tuning the Photocycle Kinetics of Bacteriorhodopsin in Lipid Nanodiscs”. Biophys J., 109(9), 1899-1906 (2015).

Huang, W. C., Tseng, T. Y., Chen, Y. T., Chang, C. C., Wang, Z. F., Wang, C. L., Hsu, T. N., Li, P. T., Chen, C. T., Lin, J. J., Lou, P. J., Chang, T. C. (2015) Direct evidence of mitochondrial G-quadruplex DNA by using fluorescent anti-cancer agents.Nucleic Acids Res. 2015 Dec 2;43(21):10102-13.

Tse, T. Y., Chang, C. C., Lin, J. J., and Chang, T. C. (2015) A Fluorescent Anti-Cancer Agent, 3,6-bis(1-methyl-4-vinylpyridinium) Carbazole Diiodide, Stains G-Quadruplexes in Cells and Inhibits Tumor Growth, Current Topics in Medicinal Chemistry 15, 1964-1970.

Epperla, C. P., Mohan, N., Chang, C. W., Chen, C. C., and Chang, H. C. (2015) Nanodiamond-Mediated Intercellular Transport of Proteins through Membrane Tunneling Nanotubes. Small. 11(45), 6097-105.