Publications

1. Shin, H., Choi, S. R., Kang, D. W., Lee, H., Park, J., Lee, M., Chae, C. W.,... & Kim, H. W. (2026). Orexin‐A Inhibits Lipopolysaccharide‐Induced Cell Migration in Cultured Mouse Astrocytes via Activation of Orexin 1 Receptor: Involvement of GABA Signaling. Journal of Cellular Biochemistry, 127(4), e70089.

2. Kim, D. H., Jo, H. Y., Oh, Y. J., Lim, J. R., Chae, C. W., Jung, Y. H., ... & Lee, H. J. (2026). Folate receptor 1 activation suppresses high glucose-induced amyloidogenesis in neurons via STAT3/Nrf2 pathway-dependent mitigation of mitochondrial oxidative stress. Biomedicine & Pharmacotherapy, 119074.

3. Lim, J. R., Chae, C. W., Yoon, J. H., Cho, J. H., Park, J. Y., Han, S. J., ... & Han, H. J. (2025). Recovery of FAM134A-mediated ER-phagy through BRD4 inhibition alleviates ethanol-induced neurodegeneration. International Journal of Biological Sciences, 21(12), 5167. [한빛사 선정]

4. Chae, C. W*., Kim, D. H., Jo, H. Y., Oh, Y. J., & Lee, H. J. (2025). Exosomes-based Applications in Companion Animals: Diagnostics and Therapeutics in Dogs and Cats. Journal of Drug Delivery Science and Technology, 106958.

5. Choi, G. E., Park, J. Y., Park, M. R., Chae, C. W., Jung, Y. H., Lim, J. R., ... & Han, H. J. (2025). Restoration of Miro1’s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation. Cell Communication and Signaling, 23(1), 166.

6. Jung YH*, Chae CW*, & Han HJ (2024). The potential role of gut microbiota-derived metabolites as regulators of metabolic syndrome-associated mitochondrial and endolysosomal dysfunction in Alzheimer’s disease. Experimental & Molecular Medicine, 1-12. [한빛사 선정]

7.  Cho JH*, Chae CW*, Lim JR, Jung YH, Han SJ, Yoon JH, …& Han HJ (2024). Sodium butyrate ameliorates high glucose-suppressed neuronal mitophagy by restoring PRKN expression via inhibiting the RELA-HDAC8 complex. Autophagy, 1-18. 

[한빛사 선정]

8. Chae CW*, Jung YH*, & Han HJ (2023). Transcription Factor EB-Mediated Lysosomal Function Regulation for Determining Stem Cell Fate under Metabolic Stress. Molecules and Cells, 46(12), 727-735. 

9. Lee HJ*, Chae CW*, & Han, H. J. (2023). Enhancing the therapeutic efficacy of mesenchymal stem cell transplantation in diabetes: Amelioration of mitochondrial dysfunction-induced senescence. Biomedicine & Pharmacotherapy, 168, 115759.

10. Chae CW, Yoon JH, Lim JR, Park JY, Cho JH, Jung YH, …& Han HJ (2023). TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ. Autophagy, 19(10), 2752-2768. [한빛사 선정]

11.  Kim MJ, Choi GE, Chae CW, Lim JR, Jung YH, Yoon JH, ... & Han HJ (2023). Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR. Cell Death & Disease, 14(2), 146.

12. Lim JR, Chae CW, Park JY, Jung YH, Yoon JH, Kim MJ, ... & Han HJ (2023). Ethanol-induced ceramide production causes neuronal apoptosis by increasing MCL-1S-mediated ER-mitochondria contacts. Neurobiology of Disease, 106009.

13. Jung YH*, Chae CW*, Chang HS, Choi GE, Lee HJ, & Han HJ (2022). Silencing SIRT5 induces the senescence of UCB-MSCs exposed to TNF-α by reduction of fatty acid β-oxidation and anti-oxidation. Free Radical Biology and Medicine, 192, 1-12.

14. Chae CW, Choi GE, Jung YH, Lim JR, Cho JH, Yoon JH, & Han HJ (2022). High glucose‐mediated VPS26a down‐regulation dysregulates neuronal amyloid precursor protein processing and tau phosphorylation. British Journal of Pharmacology, 179(15), 3934-3950.

15. Choi GE, Chae CW, Park MR, Yoon JH, Jung YH, Lee HJ, & Han HJ (2022). Prenatal glucocorticoid exposure selectively impairs neuroligin 1-dependent neurogenesis by suppressing astrocytic FGF2–neuronal FGFR1 axis. Cellular and Molecular Life Sciences, 79(6), 294.

16. Jung YH*, Chae CW*, Choi GE*, Shin HC, Lim JR, Chang HS, ... & Han HJ (2022). Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts. Journal of Biomedical Science, 29(1), 1-17. [한빛사 선정]

17. Kim JS, Jung YH, Lee HJ, Chae CW, Choi GE, Lim JR, ... & Han HJ (2021). Melatonin activates ABCA1 via the BiP/NRF1 pathway to suppress high-cholesterol-induced apoptosis of mesenchymal stem cells. Stem Cell Research & Therapy, 12(1), 1-14.

18. Choi GE, Lee HJ, Chae CW, Cho JH, Jung YH, Kim JS, ... & Han HJ (2021). BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nature communications, 12(1), 487. [한빛사 선정]

19. Lee HJ, Jung YH, Choi GE, Kim JS, Chae CW, Lim JR, ... & Han HJ (2021). Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis. Cell Death & Differentiation, 28(1), 184-202. [한빛사 선정]

20. Lim JR, Lee HJ, Jung YH, Kim JS, Chae CW, Kim SY, & Han HJ (2020). Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation. Cell Communication and Signaling, 18(1), 1-19.

21. Chae CW, Lee HJ, Choi GE, Jung YH, Kim JS, Lim JR, ... & Han HJ (2020). High glucose‐mediated PICALM and mTORC1 modulate processing of amyloid precursor protein via endosomal abnormalities. British Journal of Pharmacology, 177(16), 3828-3847.

22. Kim SY, Chae CW, Lee HJ, Jung YH, Choi GE, Kim JS, ... & Han HJ (2020). Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1. Cell death & disease, 11(6), 469.

23. Lee HJ, Jung YH, Choi GE, Kim JS, Chae CW, Lim JR, ... & Han HJ (2019). O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells. Cell Death & Disease, 10(8), 590.

24. Lee HJ, Jung YH, Choi GE, Kim JS, Chae CW, & Han HJ (2019). Role of HIF1α regulatory factors in stem cells. Int J stem cells, 12(1), 8-20.

25. Oh JY, Choi GE, Lee HJ, Jung YH, Chae CW, Kim JS, ... & Han HJ (2019). 17β-Estradiol protects mesenchymal stem cells against high glucose-induced mitochondrial oxidants production via Nrf2/Sirt3/MnSOD signaling. Free Radical Biology and Medicine, 130, 328-342.

26. Lee HJ, Jung YH, Oh JY, Choi GE, Chae CW, Kim JS, ... & Han HJ (2019). BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation. Cell Death & Differentiation, 26(9), 1716-1734. 

27. Choi GE, Oh JY, Lee HJ, Chae CW, Kim JS, Jung YH, & Han HJ (2018). Glucocorticoid-mediated ER-mitochondria contacts reduce AMPA receptor and mitochondria trafficking into cell terminus via microtubule destabilization. Cell death & disease, 9(11), 1137.

28. Oh JY, Suh HN, Choi GE, Lee HJ, Jung YH, Ko SH, Chae CW, ... & Han HJ (2018). Modulation of sonic hedgehog‐induced mouse embryonic stem cell behaviours through E‐cadherin expression and integrin β1‐dependent F‐actin formation. British Journal of Pharmacology, 175(17), 3548-3562.

29. Oh JY, Choi GE, Lee HJ, Jung YH, Ko SH, Chae CW, ... & Han HJ (2018). High glucose-induced reactive oxygen species stimulates human mesenchymal stem cell migration through snail and EZH2-dependent E-cadherin repression. Cellular Physiology and Biochemistry, 46(5), 1749-1767.

30. Gabr AA, Lee HJ, Onphachanh X, Jung YH, Kim JS, Chae CW, & Han HJ (2017). Ethanol-induced PGE2 up-regulates Aβ production through PKA/CREB signaling pathway. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1863(11), 2942-2953.

31. Ko SH, Choi GE, Oh JY, Lee HJ, Kim JS, Chae CW, ... & Han HJ (2017). Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission. Scientific reports, 7(1), 1-14.

32. Onphachanh X, Lee HJ, Lim JR, Jung YH, Kim JS, Chae CW, ... & Han HJ (2017). Enhancement of high glucose‐induced PINK1 expression by melatonin stimulates neuronal cell survival: Involvement of MT2/Akt/NF‐κB pathway. Journal of Pineal Research, 63(2), e12427. [한빛사 선정]

33. Choi GE, Lee, S. J., Lee HJ, Ko SH, Chae CW, & Han HJ (2017). Membrane-associated effects of glucocorticoid on BACE1 upregulation and Aβ generation: involvement of lipid raft-mediated CREB activation. Journal of Neuroscience, 37(35), 8459-8476.