Publications

2012 - : Ewha University

[44] Lu, Q.; Rajendran, N. M.; Bouffard, J., "Transposed N-heterocyclic olefins from the reaction of Eschenmoser hydrazones with N-heterocyclic carbenes", Org. Biomol. Chem. 2025, 23, 7746–7751. (link)

–> ChemRxiv preprint (link)

[43] Pradhan, S.; Mohammadi, F.; Tanase, R.; Amaike, K.; Itami, K.; Bouffard, J. "C–H Amination of Arenes and Heteroarenes through a Dearomative (3 + 2) Cycloaddition" J. Am. Chem. Soc. 2025, 147, 27731–27742 .(link)

–> ChemRxiv preprint (link)

[42] Rajendran, N. M.; Lu, Q.; Bouffard, J. "A Facile Preparation of N-Heterocyclic Olefins: Ring-Opening Polymerization of β-Butyrolactone and Frustrated Lewis Pair Reactivity", Chem. Eur. J. 2024, 30, e202303358. (link)

–> ChemRxiv preprint (link)

[41] Kim, G.; Luo, Y.; Shin, M.; Bouffard, J.; Bae, J.; Kim, Y. "Making the Brightest Ones Dim: Maximizing the Photothermal Conversion Efficiency of BODIPY-Based Photothermal Agents" Adv. Healthcare Mater. 2024, 13, 2400885.

[40] Keum, D.; Cho, S.; Bouffard, J.; Kim, Y. "Stimuli-triggered modulation of solid-state excimer emission in push–pull cyanovinylene dyes" J. Mater. Chem. C. 2024, 12, 47, 19227-19235.

[39] Pradhan S.; Mohammadi F.; Bouffard J.; "Skeletal Transformation of Unactivated Arenes Enabled by a Low-Temperature Dearomative (3 + 2) Cycloaddition" J. Am. Chem. Soc. 2023, 145, 22, 12214–12223. (link)

–> Highlighted in JACS 2023, 145, 11877–11878 (link)

–> ChemRxiv preprint (link)

[38] Huang, H.; Jin, Y.; Shirbhate, M. E.; Kang, D.; Choi, M.; Chen, Q.; Kim, Y.; Kim, S.-J.; Byun, I.-S.; Wang, M.; Bouffard, J.; Kim, S. K.; Kim, K. M. “Enantioselective extraction of unprotected amino acids coupled with racemization” Nature Commun. 2021, 12, 125.

[37] Kim, D.; Lee, U.; Bouffard, J.; Kim, Y. “Glycosaminoglycan-Induced Emissive J-Aggregate Formation in a meso-Ester BODIPY Dye” Adv. Opt. Mater. 2020, 1902161.

[36] Jeon, S.; Kim, T.-I.; Jin, H.; Lee, U.; Bae, J.; Bouffard, J.; Kim, Y. “Amine-Reactive Activated Esters of meso-Carboxy BODIPY: Fluorogenic Assays and Labeling of Amines, Amino Acids, and Proteins” J. Am. Chem. Soc. 2020, 142, 9231–9239.

[35] Liu, W.; Zhao, L.-L.; Melaimi, M.; Cao, L.; Xu, X.; Bouffard, J.; Bertrand, G.; Yan, X. “Mesoionic Carbene (MIC)-Catalyzed H/D Exchange” Chem 2019, 5, 2484–2494.

[34] Oh, S.; Yang, M.; Kang, S.; Chung, S.-H.; Bouffard, J.; Hong, S.; Park, S.-J. “Binary Self-Assembly of Conjugated Block Copolymers and Quantum Dots at the Air-Liquid Interface into Ordered Functional Nanoarrays”, ACS Appl. Mater. Interfaces 2019, 11, 28538–28545.

[33] Kim, T.-I.; Kim, D.; Bouffard, J.; Kim, Y. “Rapid, specific and ultrasensitive fluorogenic sensing of phosgene through an enhanced PeT mechanism”, Sens. Actuators B: Chem. 2019, 283, 458–462.

[32] Pak, Y. L.; Park, S. J.; Song, G.; Yim, Y.; Kang, H.; Kim, H. M.; Bouffard, J.; Yoon, J. “Endoplasmic Reticulum-Targeted Ratiometric N-Heterocyclic Carbene Borane Probe for Two-Photon Microscopic Imaging of Hypochlorous Acid”, Anal. Chem. 2018, 90, 12937–12943.

[31] Ping, L.; Bak, J.; Kim, Y.; Bouffard, J. “Addition, Substitution, and Ring-Contraction Reactions of Quinones with N-Heterocyclic Carbenes”, J. Org. Chem. 2018, 83, 9240–9249.

[30] Pak, Y. L.; Park, S. J.; Wu, D.; Cheon, B.; Kim, H. M.; Bouffard, J.; Yoon, J. “N-Heterocyclic Carbene Boranes as Reactive Oxygen Species-Responsive Materials: Applications to the Two-Photon Imaging of Hypochlorous Acid in Living Cells and Tissues”, Angew. Chem. Int. Ed. 2018, 57, 1567–1571.

[29] Kim, T.-I.; Hwang, B.; Bouffard, J.; Kim, Y. “Instantaneous Colorimetric and Fluorogenic Detection of Phosgene with a meso-Oxime-BODIPY”, Anal. Chem. 2017, 89, 12837–12842.

[28] Oh, S.; Yang, M.; Bouffard, J.; Hong, S.; Park S.-J. “Air-Liquid Interfacial Self-Assembly of Non-Amphiphilic Poly(3-hexylthiophene) Homopolymers”, ACS Appl. Mater. Interfaces 2017, 9, 12865–12871.

[27] Kim, T.-I.; Maity, S. B.; Bouffard, J.; Kim, Y. “Molecular Rotors for the Detection of Chemical Warfare Agent Simulants”, Anal. Chem. 2016, 88, 9259–9263.

[26] Jeon, H. J.; Kwak, M. S.; Jung, D. J.; Bouffard, J.; Lee, S.-g. “Synthesis of a-Methylene-d-Oxo-g-Amino Esters via Rh(II)-Catalyzed Coupling of 1-Sulfonyl-1,2,3-Triazoles with Morita-Baylis-Hillman Adducts”, Org. Biomol. Chem. 2016, 14, 11238–11243.

[25] Kim, S.; Bouffard, J.; Kim, Y. “Tailoring the Solid-State Fluorescence Emission of BODIPY Dyes by meso Substitution”, Chem. Eur. J. 2015, 21, 17459–17465.

[24] Han, G.; Kim, D.; Park, Y.; Bouffard, J.; Kim, Y. “Excimers Beyond Pyrene: A Far-Red Optical Proximity Reporter and its Application to the Label-Free Detection of DNA”, Angew. Chem. Int. Ed. 2015, 54, 3912–3916.

[23] Jeon, J. H.; Jung, D. J.; Kim, J. H.; Kim, Y.; Bouffard, J.; Lee, S.-g. "From Triazoles to Imidazolines through the Sequential N–H Insertion of α-Imino Rhodium–Carbenes into β-Enamino Esters/Enamine–Imine Tautomerization/Conjugate Addition Cascade", J. Org. Chem. 2014, 79, 9865–9871.

[22] Kim, J. H.; Choi, S. Y.; Bouffard, J.; Lee, S.-g. "Tandem One-Pot Synthesis of Polysubstituted NH-Pyrroles Involving the Palladium-Catalyzed Intramolecular Oxidative Amination of the Zinc Bromide Complex of β-Enamino Esters", J. Org. Chem. 2014, 79, 9253–9261.

[21] Kim, J. H.; Bouffard, J.; Lee, S.-g. "Formation of Four Different Aromatic Scaffolds from Nitriles through Tandem Divergent Catalysis", Angew. Chem. Int. Ed. 2014, 53, 6435–6438. (link)

–> Highlighted in SYNFACTS 2014, 10, 975. (link)

[20] Choi, S.; Bouffard, J.; Kim, Y. "Aggregation-Induced Emission Enhancement of a meso-Trifluoromethyl BODIPY via J-Aggregation", Chem. Sci. 2014, 5, 751–755.

[19] Xu, Q.; Lee, S.; Cho, Y.; Kim, M. H.; Bouffard, J.; Yoon, J. "Polydiacetylene-based Colorimetric and Fluorescent Chemosensor for the Detection of Carbon Dioxide", J. Am. Chem. Soc. 2013, 135, 17751–17754.

2009 - 2012 : Bertrand Lab (Posdoc Work)

[18] Yan, X.; Bouffard, J.; Guisado-Barrios, G.; Donnadieu, B.; Bertrand, G. "Anionic 1,2,3-Triazole-4,5-diylidene: a 1,2-Dihapto Ligand for Constructing Bimetallic Complexes", Chem. Eur. J. 2012, 18, 14627–14631.

[17] Guisado-Barrios, G.; Bouffard, J.; Donnadieu, B.; Bertrand, G. "Bis(1,2,3-triazol-5-ylidenes) (i-bitz) as Stable 1,4-Bidentate Ligands Based on Mesoionic Carbenes (MICs)", Organometallics 2011, 30, 6017–6021.

[16] Keitz, B. K.; Bouffard, J.; Bertrand, G.; Grubbs, R. H. "Protonolysis of a Ruthenium-Carbene Bond and Applications in Olefin Metathesis", J. Am. Chem. Soc. 2011, 133, 8498–8501.

[15] Ung, G.; Mendoza-Espinosa, D.; Bouffard, J.; Bertrand, G. "A Stable Acyclic Ligand Equivalent of an Unstable 1,3-Dithiol-5-ylidene", Angew. Chem. Int. Ed. 2011, 50, 4215–4218.

[14] Bouffard, J.; Keitz, B. K.; Tonner, R.; Guisado-Barrios, G.; Frenking, G.; Grubbs, R. H.; Bertrand, G. "Synthesis of Highly Stable 1,3-Diaryl-1H-1,2,3-triazol-5-ylidenes and Their Applications in Ruthenium-Catalyzed Olefin Metathesis", Organometallics 2011, 30, 2617–2627.

[13] Guisado-Barrios, G.; Bouffard, J.; Donnadieu, B.; Bertrand, G. "Crystalline 1H-1,2,3-Triazol-5-ylidenes: New Stable Mesoionic Carbenes (MICs)", Angew. Chem. Int. Ed. 2010, 49, 4759–4762.

2007 - 2009 : Itami Lab (Postdoc Work)

[12] Bouffard, J.; Watanabe, M.; Takaba, H.; Itami, K. "Photopatterning of Poly(arylene dienylene) by the Photoacid-Catalyzed Deprotection-Elimination Reaction of a Precursor Polymer", Macromolecules 2010, 43, 1425–1429.

[11] Bouffard, J.; Itami, K. "A Nickel Catalyst for the Addition of Organoboronate Esters to Ketones and Aldehydes", Org. Lett. 2009, 11, 4410-4413.

[10] Takaba, H.; Omachi, H.; Yamamoto, Y.; Bouffard, J.; Itami, K. "Selective Synthesis of [12]Cycloparaphenylene", Angew. Chem. Int. Ed. 2009, 48, 6112-6116.

[9] Mori, S.; Nambo, M.; Chi, L.-C.; Bouffard, J.; Itami, K. "A Bench-Stable Pd Catalyst for the Hydroarylation of Fullerene with Boronic Acids", Org. Lett. 2008, 10, 4609-4612.

2002 - 2007 : Swager Lab (Ph. D. Work)

[8] Bouffard, J.; Swager, T. M. "Self-assembly of amphiphilic poly(phenylene ethynylene)s in water-potassium dodecanoate-decanol lyotropic liquid crystals", Chem. Comm. 2008, 5387-5389.

[7] Chen, Z.; Bouffard, J.; Kooi, S. E.; Swager, T. M.; "Highly Emissive Iptycene-Fluorene Conjugated Copolymers: Synthesis and Photophysical Properties", Macromolecules 2008, 41, 6672–6676.

[6] Bouffard, J.; Swager, T. M.; "Fluorescent Conjugated Polymers that Incorporate Substituted 2,1,3-Benzooxadiazole and 2,1,3-Benzothiadiazole Units", Macromolecules 2008, 41, 5559–5562.

[5] Bouffard, J.; Kim, Y.; Swager, T. M.; Weissleder, R.; Hilderbrand, S. A. "A Highly Selective Fluorescent Probe for Thiol Bioimaging", Org. Lett. 2008, 10, 37–40.

[4] Bouffard, J.; Eaton, R. F.; Müller, P.; Swager, T. M. "Iptycene-Derived Pyridazines and Phthalazines", J. Org. Chem. 2007, 72, 10166–10180.

[3] Ishow, E.; Bouffard J.; Kim, Y.; Swager, T.M. "Anthryl-Based Poly(phenylene ethynylene)s: Tuning Optical Properties with Diels-Alder Reactions", Macromolecules, 2006, 39, 7854–7858.

[2] Kim, Y.; Bouffard, J.; Kooi, S. E.; Swager, T. M. "Highly Emissive Conjugated Polymer Excimers", J. Am. Chem. Soc., 2005, 127, 13726–13731.

2001 - 2002 : Sleiman Lab (B. Sc. Work)

[1] Bazzi, H. S.; Bouffard, J.; Sleiman H. F. "Self-Complementary ABC Triblock Copolymers via Ring-Opening Metathesis Polymerization", Macromolecules, 2003, 36, 7899–7902. (link)

Patents

[2] Swager, T. M.; Andrew, T. L.; Thomas, S. W.; Bouffard, J. “Determination of Explosives Including RDX”, US 7,862,775 B2.

[1] Swager, T. M.; Bouffard, J. “High Internal Free Volume Compositions for Low-K Dielectric and Other Applications”, pending, U. S. Pat. Apl. Ser. No. 11/336,417 filed 01/20/2006.

Review & Book Chapters

[3] Ping, L.; Chung, D. S.; Bouffard, J.; Lee, S.-g. “Transition metal-catalyzed site- and regio-divergent C–H bond functionalization”, Chem. Soc. Rev. 2017, 46, 4299–4328.

[2] Kim, J. H.; Ko, Y. O.; Bouffard, J.; Lee, S.-g. “Advances in tandem reactions with organozinc reagents”, Chem. Soc. Rev. 2015, 44, 2489–2507.

[1] Bouffard, J.; Itami, K. "Rhodium-Catalyzed C-H Bond Arylation of Arenes", Top. Curr. Chem. 2010, 292, 231–280.

Others

[13] Swager, T. M.; Bouffard, J. “A Quick Approach to Valuable Building Blocks Using Multiple Benzidine Rearrangements”, Synfacts 2006, 8, 781.

[12] Swager, T. M.; Bouffard, J. “Planarization of Conjugated Biaryls through B-N Interactions”, Synfacts 2006, 8, 790.

[11] Swager, T. M.; Bouffard, J. “An Orthogonal Protection-Deprotection Route to Antipodal Fullerene Derivatives”, Synfacts 2006, 7, 666.

[10] Swager, T. M.; Bouffard, J. “Fully Conjugated PPV Dendrimers”, Synfacts 2006, 7, 670.

[9] Swager, T. M.; Bouffard, J. “Fluorescent Dyes Highly Aligned in Nematic Liquid Crystals”, Synfacts 2006, 6, 564.

[8] Swager, T. M.; Bouffard, J. “Ultramicroporous Polymers for Hydrogen Storage by Design”, Synfacts 2006, 6, 565.

[7] Swager, T. M.; Bouffard, J. “Light-Induced Chirality in a Liquid Crystal”, Synfacts 2006, 5, 448.

[6] Swager, T. M.; Bouffard, J. “Pi-Extended Perylenebisimide Near IR Dyes”, Synfacts 2006, 5, 449.

[5] Swager, T. M.; Bouffard, J. “Alignment of Conjugated Polymers by Threading through Porphyrin Tweezers”, Synfacts 2006, 5, 529.

[4] Swager, T. M.; Bouffard, J. “PEDOT vs. PEDTT: Subtle Variations, Large Consequences”, Synfacts 2006, 4, 329.

[3] Swager, T. M.; Bouffard, J. “Cross-Linking Through the Core of a Mesogen”, Synfacts 2006, 4, 331.

[2] Swager, T. M.; Bouffard, J. “Ruthenium-Catalyzed Alternating ROMP Polymerizations”, Synfacts 2006, 3, 229.

[1] Swager, T. M.; Bouffard, J. “Synthetic Anion-Binding Macrocyclic Heterocycles”, Synfacts 2006, 3, 218.

Page updated

Report abuse