Evolution Biology of Aging, Cellular Senescence and Tumor Suppression
Irena Manov
Irena Manov
Title: Associate Professor of the Institute of Evolution, University of Haifa
Title: Associate Professor of the Institute of Evolution, University of Haifa
Office: Multi-Purpose Building, Room 224 199 Aba-Khoushy Avenue, Mt. Carmel, Haifa, 3498838, Israel
Office: Multi-Purpose Building, Room 224 199 Aba-Khoushy Avenue, Mt. Carmel, Haifa, 3498838, Israel
Phone: + 972-4-6647954
Phone: + 972-4-6647954
Mobile: + 972-545243408
Mobile: + 972-545243408
Subject:
Aging and cellular senescence in long-lived, hypoxia-tolerant and cancer-resistant subterranean rodent, Spalax
1 Anti-inflammatory network in senescent cells and aging tissues of Spalax: role of NF-kB pathway;
2 Mechanisms of suppression of malignant behavior of cancer cells under the Influence of paracrine factors of Spalax senescent cells;
3 Mechanisms of skeletal muscle aging and regeneration in Spalax. How does Spalax prevent sarcopenia and maintain high mobility throughout life?