Currently many Neurodevelopmental Disorders (NDDs) have been proved by biological experiments to have correlation with cell signaling malfunctions in prenatal and postnatal cortical components. Researchers need effective and relatively easy to use computational tools to support their research of but not limited to discovering putative ligand-receptor interactions in the brain to proliferate more potential focus of research, findings, and design of novel treatments for NDDs. Our computational tools with visualization would assist biological lab researchers who have a certain level of computational proficiency in their research model.
Research laboratories and biotech companies need to consistently output novel research/product development in order to maintain their funding (grants, venture capital, etc.). Labs and companies could sell the computational tool to other labs and companies who want to use the tool to maintain their funding. Products developed by taking advantage of the computational tool could also be sold to NDD patients who need treatment to earn profits. To be more specific, a versatile tool that could be used for any type of signaling pathway could conceivably find use in ~½ of microbiology labs and/or the computational cores that support them. ~200 labs at UCSD, ~5,000 labs in California, 10,000-100,000 labs around the United States and internationally. Numbers could be increased by 20-100% when companies are included.