Fabricate miniaturized attachment integrating imaging and fluorescence microscopy.
Create a Time-series model of immunoassay to determine analyte concentration.
Quantify TBI severity based on GFAP concentration
Outline of our projected plans to complete the project.
Hardware
Optical Filtering. Learned how to create a system that both emits specified wavelengths and accepts/analyze specified wavelengths.
Microcontroller programming. Used both Arduino and Raspberry Pi in data collection and data pre-processing. Learned multi-device communication along with utilizing peripheral devices.
Designing trials for clinical validation and approval of regulatory bodies.
Computer-aided design of 3D models and finite element analysis. Development of final prototype on Solidworks and AutoCAD. Learned how to apply a finite element analysis on the compartment to ensure that it would be safe to use.
Software
Statistical Analysis. Learned how to combine data from several sources and integrate them into a single larger set based on parameter estimation and defining multi-variable transformations to translate data.
Extrapolation. Using representative statistics to simulate a larger data set to test for proof of concept against known methods of diagnosis.
Image Signal Processing. Development of image processing algorithm with accuracy, reproducibility, and efficiency in mind.
Mathematical Modeling. Implementation of a mathematical model to make use of the information encapsulated in the transient dynamics of the test for better diagnosis.