“Support Cancer Research | Why Donate To Cancer Research.” ACRF, www.acrf.com.au/support-cancer-research/.
Because every sixth death in the world is caused by cancer; at this mortality rate, cancer is the second most deadly disease globally. In the United States, the American Cancer Society estimates that nearly 600,000 individuals die from cancer annually. Due to the nature of the disease, a cure currently is not viable and current treatment options have much greater success rates when started in the early stages of cancer. Therefore, there is an urgent need for early disease detection techniques to diagnose and monitor disease when at a controllable stage.
Cancer is caused by cancer inducing mutations which causes cells to multiply uncontrollably. As the number of cancerous cells increase, the chances of it metastasising increases meaning that it spreads and grows throughout your body. Thus the best way to combat cancer is to identify it while it is localized and in its early stages then remove via treatment such as surgery or chemotherapy.
One way to detect cancer and other diseases early on is through the use of biomarkers. A biomarker is a biology substance that can be quantified within the body that is indicative of a biological function/phenomenon, environmental influences, and disease. When cancerous cells grow, divide, and die, they can produce biomarkers like proteins which can be detected. Biomarkers that are already used for disease detection include cholesterol, where elevated levels can indicate an increase in chances of heart disease. Similarly, elevated levels of HER2 protein can be used to diagnose breast cancer and PSA for prostate cancer. Through better understanding of which biomarkers to identify and how to quantify these biomarkers, early detection can be made possible for a variety of diseases.