Publications

< 2024 >

89. Kim HR, Lee HJ, Jeon Y, Jang SY, Shin YK, Yun JH, Park HJ, Koh H, Lee KE, Shin JE, Park HT, Targeting SARM1 improves autophagic stress-induced axonal neuropathy. Autophagy. 2024 Jan;20(1):29-44. PMID: 37561040 

< 2023 >

88. Jo YR, Oh Y, Kim YH, Shin YK, Kim HR, Go H; Shin JK, Park HJ, Koh HJ, Kim JK, Shin JE, Lee KE, Park HT, Adaptive autophagy reprogramming in Schwann cells during peripheral demyelination. Cell Mol Life Sci. 2023 Jan 9;80(1):34. PMID: 36622429

87. Shin YK, Jo YR, Lee SH, Park HT, Shin JE, Regulation of the V-ATPase subunit ATP6V0D2 and its role in demyelination after peripheral nerve injury Biochem Biophys Res Commun.< 2023 Feb 26;646:1-7. PMID: 36689911

86. Han SH, Kim YH, Park SJ, Cho JG, Shin YK, Hong YB, Yun JH, Han JY, Park HT, Park JI, COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20. J Neurochem. 2023 Jun;165(5):660-681. PMID: 36648143

85. Kim YH, Yoon BA, Jo YR, Nam SH, Kim NH, Kim KH, Kim JK, Choi BO, Park HT, Neural cell adhesion molecule 1 is a cellular target engaged plasma biomarker in demyelinating Charcot-Marie-Tooth disease. Eur J Neurol. 2023 Jun;30(6):1745-1754. PMID: 36856547

< 2022 >

84. Jo YR, Park HT, Yu HS, Kong HH, Trichinella Infection Ameliorated Vincristine-Induced Neuroinflammation in Mice. Korean J Parasitol . 2022 Aug;60(4):247-254. PMID: 36041486 

< 2021 >

83. Yoon BA, Ha DH, Park HT, Kusunoki S, Kuwahara M, Lee JH, Bae JS, Kim JK. Finger drop sign as a new variant of acute motor axonal neuropathy. Muscle Nerve. 2021 Mar;63(3):336-343. doi: 10.1002/mus.27126. Epub 2020 Dec 22. PMID: 33217007.

82. Byeon JW, Jo YR, Shin YK, Park HT, Park HS. Scaffolding protein Gab2 is involved in postnatal development and lipopolysaccharide-induced activation of microglia in the mouse brain.Biochemical and Biophysical Research Communications. 2021 Aug 27;567:112-117. doi: 10.1016/j.bbrc.2021.06.028. Epub 2021 Jun 17. PMID: 34146905

81. Jo YR, Kim HR, Jang SY, Go H, Song MY, Park DK, Oh Y, Jo J, Shin YK, Lee SJ, Cheon SM, Lee HK, Lee KE, Kim YH, Park HT. Potential neuron-autonomous Purkinje cell degeneration by 2',3'-cyclic nucleotide 3'-phosphodiesterase promoter/Cre-mediated autophagy impairments. The FASEB Journal. 2021 Jan;35(1):e21225. doi: 10.1096/fj.202001366RR. PMID: 33337568

< 2020 >

80. Sohn EJ, Park HT, Shin YK. Exosomes derived from differentiated Schwann cells inhibit Schwann cell migration via microRNAs. Neuroreport. 2020 May 7;31(7):515-522. doi: 10.1097/WNR.0000000000001435. PMID: 32282580.

79. Sohn EJ, Park HT. Differential expression of circular RNAs in the proximal and distal segments of the sciatic nerve after injury. Neuroreport. 2020 Jan 8;31(1):76-84. doi: 10.1097/WNR.0000000000001371. PMID: 31764243.

78. Song GJ, Gupta DP, Rahman MH, Park HT, Al Ghouleh I, Bisello A, Lee MG, Park JY, Park HH, Jun JH, Chung KW, Choi BO, Suk K. Loss-of-function of EBP50 is a new cause of hereditary peripheral neuropathy: EBP50 functions in peripheral nerve system. Glia. 2020 Sep;68(9):1794-1809. doi: 10.1002/glia.23805. Epub 2020 Feb 20. PMID: 32077526.

77. Park HT, Kim YH, Lee KE, Kim JK. Behind the pathology of macrophage-associated demyelination in inflammatory neuropathies: demyelinating Schwann cells. Cell Mol Life Sci. 2020 Jul;77(13):2497-2506. doi: 10.1007/s00018-019-03431-8. Epub 2019 Dec 28. PMID: 31884566; PMCID: PMC7320037.

< 2019 >

76. Sohn EJ, Park HT. Differential expression of circular RNAs in the proximal and distal segments of the sciatic nerve after injury. Neuroreport. 2020 Jan 8;31(1):76-84. doi: 10.1097/WNR.0000000000001371. PMID: 31764243.

75. Kim YH, Jang SY, Shin YK, Jo YR, Yoon BA, Nam SH, Choi BO, Shin HY, Kim SW, Kim SH, Kim JK, Park HT. Serum CXCL13 reflects local B-cell mediated inflammatory demyelinating peripheral neuropathy. Sci Rep. 2019 Nov 11;9(1):16535. doi: 10.1038/s41598-019-52643-2. PMID: 31712675; PMCID: PMC6848485.

74. Han SH, Yun SH, Shin YK, Park HT, Park JI. Heat Shock Protein 90 is Required for cAMP-Induced Differentiation in Rat Primary Schwann Cells. Neurochem Res. 2019 Nov;44(11):2643-2657. doi: 10.1007/s11064-019-02885-3. Epub 2019 Oct 12. PMID: 31606837.

73. Sohn EJ, Jo YR, Park HT. Downregulation MIWI-piRNA regulates the migration of Schwann cells in peripheral nerve injury. Biochem Biophys Res Commun. 2019 Nov 12;519(3):605-612. doi: 10.1016/j.bbrc.2019.09.008. Epub 2019 Sep 17. PMID: 31540693.

72. Kim YH, Kim YH, Shin YK, Jo YR, Park DK, Song MY, Yoon BA, Nam SH, Kim JH, Choi BO, Shin HY, Kim SW, Kim SH, Hong YB, Kim JK, Park HT. p75 and neural cell adhesion molecule 1 can identify pathologic Schwann cells in peripheral neuropathies. Ann Clin Transl Neurol. 2019 Jul;6(7):1292-1301. doi: 10.1002/acn3.50828. Epub 2019 Jul 2. PMID: 31353867; PMCID: PMC6649441.

71. Ryu WY, Kim YH, Yoon BA, Park HT, Bae JS, Kim JK. Pattern of Extraocular Muscle Involvements in Miller Fisher Syndrome. J Clin Neurol. 2019 Jul;15(3):308-312. doi: 10.3988/jcn.2019.15.3.308. PMID: 31286701; PMCID: PMC6620438.

70. Lee JS, Kwak G, Kim HJ, Park HT, Choi BO, Hong YB. miR-381 Attenuates Peripheral Neuropathic Phenotype Caused by Overexpression of PMP22. Exp Neurobiol. 2019 Apr;28(2):279-288. doi: 10.5607/en.2019.28.2.279. Epub 2019 Apr 30. PMID: 31138995; PMCID: PMC6526106.

69. Kim YY, Um JH, Yoon JH, Kim H, Lee DY, Lee YJ, Jee HJ, Kim YM, Jang JS, Jang YG, Chung J, Park HT, Finkel T, Koh H, Yun J. Assessment of mitophagy in mt-Keima Drosophila revealed an essential role of the PINK1-Parkin pathway in mitophagy induction in vivo. FASEB J. 2019 Sep;33(9):9742-9751. doi: 10.1096/fj.201900073R. Epub 2019 May 23. PMID: 31120803.

68. Chang EH, Mo WM, Doo HM, Lee JS, Park HT, Choi BO, Hong YB. Aminosalicylic acid reduces ER stress and Schwann cell death induced by MPZ mutations. Int J Mol Med. 2019 Jul;44(1):125-134. doi: 10.3892/ijmm.2019.4178. Epub 2019 May 2. PMID: 31059078; PMCID: PMC6559330.

67. Park JE, Kim YJ, Lee SG, Kim JY, Chung JY, Jeong SY, Koh H, Yun J, Park HT, Yoo YH, Kim JM. Drp1 Phosphorylation Is Indispensable for Steroidogenesis in Leydig Cells. Endocrinology. 2019 Apr 1;160(4):729-743. doi: 10.1210/en.2019-00029. PMID: 30689811.

66. Jeong JY, Cha HJ, Choi EO, Kim CH, Kim GY, Yoo YH, Hwang HJ, Park HT, Yoon HM, Choi YH. Activation of the Nrf2/HO-1 signaling pathway contributes to the protective effects of baicalein against oxidative stress-induced DNA damage and apoptosis in HEI193 Schwann cells. Int J Med Sci. 2019 Jan 1;16(1):145-155. doi: 10.7150/ijms.27005. PMID: 30662338; PMCID: PMC6332480.

65. Park C, Choi EO, Kim GY, Hwang HJ, Kim BW, Yoo YH, Park HT, Choi YH. Protective Effect of Baicalein on Oxidative Stress-induced DNA Damage and Apoptosis in RT4-D6P2T Schwann Cells. Int J Med Sci. 2019 Jan 1;16(1):8-16. doi: 10.7150/ijms.29692. PMID: 30662323; PMCID: PMC6332490.

64. Heo K, Lim SM, Nahm M, Kim YE, Oh KW, Park HT, Ki CS, Kim SH, Lee S. A De Novo RAPGEF2 Variant Identified in a Sporadic Amyotrophic Lateral Sclerosis Patient Impairs Microtubule Stability and Axonal Mitochondria Distribution. Exp Neurobiol. 2018 Dec;27(6):550-563. doi: 10.5607/en.2018.27.6.550. Epub 2018 Dec 12. PMID: 30636905; PMCID: PMC6318558.

63. Sohn EJ, Nam YK, Park HT. MicroRNAs 93-5p, 106b-5p, 17-5p, and 140-5p target the expression of early growth response protein 2 in Schwann cells. Neuroreport. 2019 Feb 6;30(3):241-246. doi: 10.1097/WNR.0000000000001193. PMID: 30614908.

< 2018 >

62. Sohn EJ, Bak KM, Nam YK, Park HT. Upregulation of microRNA 344a-3p is involved in curcumin induced apoptosis in RT4 schwannoma cells. Cancer Cell Int. 2018 Dec 4;18:199. doi: 10.1186/s12935-018-0693-x. PMID: 30534000; PMCID: PMC6278133.

61. Kim SY, Jin CY, Kim CH, Yoo YH, Choi SH, Kim GY, Yoon HM, Park HT, Choi YH. Isorhamnetin alleviates lipopolysaccharide-induced inflammatory responses in BV2 microglia by inactivating NF-κB, blocking the TLR4 pathway and reducing ROS generation. Int J Mol Med. 2019 Feb;43(2):682-692. doi: 10.3892/ijmm.2018.3993. Epub 2018 Nov 20. PMID: 30483725; PMCID: PMC6317673.

60. Park HT, Kim JK, Tricaud N. The conceptual introduction of the "demyelinating Schwann cell" in peripheral demyelinating neuropathies. Glia. 2019 Apr;67(4):571-581. doi: 10.1002/glia.23509. Epub 2018 Oct 30. PMID: 30378179.

59. Lee SW, Park JB, Kim HJ, Kim HY, Lee SY, Chung WT, Shin YK, Park HT, Rho JH, Yoo YH. Palmitate induces lipoapoptosis in Schwann cells through ROS generation-mediated STAMP2 downregulation. Biochem Biophys Res Commun.2018 Sep 10;503(3):1260-1266. doi: 10.1016/j.bbrc.2018.07.034. Epub 2018 Jul 11. PMID: 30005874.

58. Sohn EJ, Park HT. MicroRNA Mediated Regulation of Schwann Cell Migration and Proliferation in Peripheral Nerve Injury. Biomed Res Int. 2018 Apr 30;2018:8198365. doi: 10.1155/2018/8198365. PMID: 29854793; PMCID: PMC5952561.

< 2017 >

57. Sohn EJ, Park HT. Natural agents mediated autophagic signal networks in cancer. Cancer Cell Int. 2017 Nov 28;17:110. doi: 10.1186/s12935-017-0486-7. PMID: 29209152; PMCID: PMC5704453.

56. Yang J, Kim MJ, Yoon W, Kim EY, Kim H, Lee Y, Min B, Kang KS, Son JH, Park HT, Chung J, Koh H. Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH). PLoS Genet. 2017 Aug 21;13(8):e1006975. doi: 10.1371/journal.pgen.1006975. PMID: 28827794; PMCID: PMC5578699.

55. Jang SY, Yoon BA, Shin YK, Yun SH, Jo YR, Choi YY, Ahn M, Shin T, Park JI, Kim JK, Park HT. Schwann cell dedifferentiation-associated demyelination leads to exocytotic myelin clearance in inflammatory segmental demyelination. Glia. 2017 Nov;65(11):1848-1862. doi: 10.1002/glia.23200. Epub 2017 Aug 10. PMID: 28795433.

54. Shin YK, Jang SY, Yun SH, Choi YY, Yoon BA, Jo YR, Park SY, Pak MG, Park JI, Park HT. Cooperative interaction of hepatocyte growth factor and neuregulin regulates Schwann cell migration and proliferation through Grb2-associated binder-2 in peripheral nerve repair. Glia. 2017 Nov;65(11):1794-1808. doi: 10.1002/glia.23195. Epub 2017 Jul 19. PMID: 28722233.

53. Park SY, Jang SY, Shin YK, Jung DK, Yoon BA, Kim JK, Jo YR, Lee HJ, Park HT. The Scaffolding Protein, Grb2-associated Binder-1, in Skeletal Muscles and Terminal Schwann Cells Regulates Postnatal Neuromuscular Synapse Maturation. Exp Neurobiol. 2017 Jun;26(3):141-150. doi: 10.5607/en.2017.26.3.141. Epub 2017 Jun 16. PMID: 28680299; PMCID: PMC5491582.

52. Ghidinelli M, Poitelon Y, Shin YK, Ameroso D, Williamson C, Ferri C, Pellegatta M, Espino K, Mogha A, Monk K, Podini P, Taveggia C, Nave KA, Wrabetz L, Park HT, Feltri ML. Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination. PLoS Biol. 2017 Jun 21;15(6):e2001408. doi: 10.1371/journal.pbio.2001408. PMID: 28636612; PMCID: PMC5479503.

51. Tricaud N, Park HT. Wallerian demyelination: chronicle of a cellular cataclysm. Cell Mol Life Sci. 2017 Nov;74(22):4049-4057. doi: 10.1007/s00018-017-2565-2. Epub 2017 Jun 9. PMID: 28600652; PMCID: PMC5641270.

50. Lee JS, Chang EH, Koo OJ, Jwa DH, Mo WM, Kwak G, Moon HW, Park HT, Hong YB, Choi BO. Pmp22 mutant allele-specific siRNA alleviates demyelinating neuropathic phenotype in vivo. Neurobiol Dis. 2017 Apr;100:99-107. doi: 10.1016/j.nbd.2017.01.006. Epub 2017 Jan 17. PMID: 28108290.

< 2016 >

49. Kim JK, Hong SK, Bae JS, Yoon BA, Park HT, Huh SY, Kim SJ, Kim JE, Kim DS. Ophthalmoplegic Guillain-Barré syndrome: An independent entity or a transitional spectrum? J Clin Neurosci. 2016 Oct;32:19-23. doi: 10.1016/j.jocn.2015.11.034. Epub 2016 Jul 18. PMID: 27436763.

48. Hong YB, Joo J, Hyun YS, Kwak G, Choi YR, Yeo HK, Jwa DH, Kim EJ, Mo WM, Nam SH, Kim SM, Yoo JH, Koo H, Park HT, Chung KW, Choi BO. A Mutation in PMP2 Causes Dominant Demyelinating Charcot-Marie-Tooth Neuropathy. PLoS Genet. 2016 Feb 1;12(2):e1005829. doi: 10.1371/journal.pgen.1005829. PMID: 26828946; PMCID: PMC4735456.

47. Kim JK, Kim BJ, Shin HY, Shin KJ, Nam TS, Oh J, Suh BC, Yoon BA, Park HT, Huh SY, Oh SI, Bae JS; Korean Inflammatory Neuropathy Consortium. Acute bulbar palsy as a variant of Guillain-Barré syndrome. Neurology. 2016 Feb 23;86(8):742-7. doi: 10.1212/WNL.0000000000002256. Epub 2015 Dec 30. PMID: 26718574. 46. Jang SY, Shin YK, Park SY, Park JY, Lee HJ, Yoo YH, Kim JK, Park HT. Autophagic myelin destruction by Schwann cells during Wallerian degeneration and segmental demyelination. Glia. 2016 May;64(5):730-42. doi: 10.1002/glia.22957. Epub 2015 Dec 29. PMID: 26712109.

< 2015 >

45. Yoo SH, Kim HY, Rho JH, Jeong SY, Yun J, Yun I, Park HT, Yoo YH. Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level.
Int J Oncol. 2015 Nov;47(5):1783-92. doi: 10.3892/ijo.2015.3150. Epub 2015 Sep 7. PMID: 26351876.

44. Jang SY, Shin YK, Park SY, Park JY, Rha SH, Kim JK, Lee HJ, Park HT. Autophagy is involved in the reduction of myelinating Schwann cell cytoplasm during myelin maturation of the peripheral nerve. PLoS One. 2015 Jan 12;10(1):e0116624. doi: 10.1371/journal.pone.0116624. PMID: 25581066; PMCID: PMC4291222.

43 Ha DH, Choi S, Kang EJ, Park HT. Diffusion tensor imaging and T2 mapping in early denervated skeletal muscle in rats. J Magn Reson Imaging. 2015 Sep;42(3):617-23. doi: 10.1002/jmri.24818. Epub 2014 Dec 11. PMID: 25504841.

< 2014 >

42. Kim JK, Lee HJ, Park HT. Two faces of Schwann cell dedifferentiation in peripheral neurodegenerative diseases: pro-demyelinating and axon-preservative functions. Neural Regen Res. 2014 Nov 15;9(22):1952-4. doi: 10.4103/1673-5374.145370. PMID: 25598775; PMCID: PMC4283275.

41. Lee HJ, Shin YK, Park HT. Mitogen Activated Protein Kinase Family Proteins and c-jun Signaling in Injury-induced Schwann Cell Plasticity. Exp Neurobiol. 2014 Jun;23(2):130-7. doi: 10.5607/en.2014.23.2.130. Epub 2014 Jun 13. PMID: 24963277; PMCID: PMC4065826.

40. Shin YK, Jang SY, Park SY, Park JY, Kim JK, Kim JP, Suh DJ, Lee HJ, Park HT. Grb2-associated binder-1 is required for neuregulin-1-induced peripheral nerve myelination. J Neurosci. 2014 May 28;34(22):7657-62. doi: 10.1523/JNEUROSCI.4947-13.2014. PMID: 24872569; PMCID: PMC6795250.

39. Kim DK, Jeong JH, Lee JM, Kim KS, Park SH, Kim YD, Koh M, Shin M, Jung YS, Kim HS, Lee TH, Oh BC, Kim JI, Park HT, Jeong WI, Lee CH, Park SB, Min JJ, Jung
SI, Choi SY, Choy HE, Choi HS. Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis. Nat Med. 2014 Apr;20(4):419-24. doi: 10.1038/nm.3483. Epub 2014 Mar 23. PMID: 24658075.

38. Gu TW, Bae WY, Park HT, Lee JH, Kang MY, Jeong SW, Shin YK. Expression profile of fas-fas ligand in spiral ganglion cells during apoptosis. Clin Exp Otorhinolaryngol. 2014 Mar;7(1):1-6. doi: 10.3342/ceo.2014.7.1.1. Epub 2014 Feb 5. PMID: 24587873; PMCID: PMC3932342.

< 2013 >

37. Park JY, Jang SY, Shin YK, Suh DJ, Park HT. Calcium-dependent proteasome activation is required for axonal neurofilament degradation. Neural Regen Res. 2013 Dec 25;8(36):3401-9. doi: 10.3969/j.issn.1673-5374.2013.36.005. PMID: 25206662; PMCID: PMC4146008.

36. Shin YK, Jang SY, Park JY, Park SY, Lee HJ, Suh DJ, Park HT. The Neuregulin-Rac-MKK7 pathway regulates antagonistic c-jun/Krox20 expression in Schwann cell dedifferentiation. Glia. 2013 Jun;61(6):892-904. doi: 10.1002/glia.22482. Epub 2013 Mar 15. PMID: 23505039.

< 2012 >

35. Lee JS, Kim HY, Jeong NY, Lee SY, Yoon YG, Choi YH, Yan C, Chu IS, Koh H, Park HT, Yoo YH. Expression of αB-crystallin overrides the anti-apoptotic activity of XIAP. Neuro Oncol. 2012 Nov;14(11):1332-45. doi: 10.1093/neuonc/nos247. Epub 2012 Oct 16. PMID: 23074197; PMCID: PMC3480270.

34. Jang SY, Shin YK, Lee HY, Park JY, Suh DJ, Kim JK, Bae YS, Park HT. Local production of serum amyloid a is implicated in the induction of macrophage chemoattractants in Schwann cells during wallerian degeneration of peripheral nerves. Glia. 2012 Oct;60(10):1619-28. doi: 10.1002/glia.22382. Epub 2012 Jul 9. PMID: 22777957.

< 2011 >

33. Park HT, Feltri ML. Rac1 GTPase controls myelination and demyelination. Bioarchitecture. 2011 May;1(3):110-113. doi: 10.4161/bioa.1.3.16985. PMID: 21922040; PMCID: PMC3173960.

32. Jung J, Cai W, Jang SY, Shin YK, Suh DJ, Kim JK, Park HT. Transient lysosomal activation is essential for p75 nerve growth factor receptor expression in myelinated Schwann cells during Wallerian degeneration. Anat Cell Biol. 2011 Mar;44(1):41-9. doi: 10.5115/acb.2011.44.1.41. Epub 2011 Mar 31. PMID: 21519548; PMCID: PMC3080007.

31. Jung J, Cai W, Lee HK, Pellegatta M, Shin YK, Jang SY, Suh DJ, Wrabetz L, Feltri ML, Park HT. Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration. J Neurosci. 2011 Feb 9;31(6):2009-15. doi: 10.1523/JNEUROSCI.4537-10.2011. PMID: 21307239; PMCID: PMC3071261.         .

< 2010 >

30. Shin YK, Jang SY, Lee HK, Jung J, Suh DJ, Seo SY, Park HT. Pathologicaladaptive responses of Schwann cells to endoplasmic reticulum stress in bortezomib-induced peripheral neuropathy. Glia. 2010 Dec;58(16):1961-76. doi: 10.1002/glia.21065. PMID: 20830808.

29. Jang SY, Shin YK, Jung J, Lee SH, Seo SY, Suh DJ, Park HT. Injury-induced CRMP4 expression in adult sensory neurons; a possible target gene for ciliary neurotrophic factor. Neurosci Lett. 2010 Nov 12;485(1):37-42. doi: 10.1016/j.neulet.2010.08.058. Epub 2010 Aug 26. PMID: 20800647.

28. Joe Y, Do MH, Seo E, Kang S, Park HT, Yun J, Lee HJ. Fenofibrate antagonizes Chk2 activation by inducing Wip1 expression: implications for cell proliferation and tumorigenesis. Life Sci. 2010 May 8;86(19-20):716-21. doi: 10.1016/j.lfs.2010.03.006. Epub 2010 Mar 11. PMID: 20226795.     .

< 2009 >

27. Lee HK, Jung J, Lee SH, Seo SY, Suh DJ, Park HT. Extracellular Signal-regulated Kinase Activation Is Required for Serine 727 Phosphorylation of STAT3 in Schwann Cells in vitro and in vivo. Korean J Physiol Pharmacol. 2009 Jun;13(3):161-8. doi: 10.4196/kjpp.2009.13.3.161. Epub 2009 Jun 30. PMID: 19885032; PMCID: PMC2766727.

26. Seo IA, Lee HK, Shin YK, Lee SH, Seo SY, Park JW, Park HT. Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130. Korean J Physiol Pharmacol. 2009 Apr;13(2):131-8. doi: 10.4196/kjpp.2009.13.2.131. Epub 2009 Apr 30. PMID: 19885008; PMCID: PMC2766696.

25. Lee HK, Seo IA, Suh DJ, Park HT. Nidogen plays a role in the regenerative axon growth of adult sensory neurons through Schwann cells. J Korean Med Sci. 2009 Aug;24(4):654-9. doi: 10.3346/jkms.2009.24.4.654. Epub 2009 Jul 29. PMID: 19654948; PMCID: PMC2719197.

24. Lee HK, Shin YK, Jung J, Seo SY, Baek SY, Park HT. Proteasome inhibition suppresses Schwann cell dedifferentiation in vitro and in vivo. Glia. 2009 Dec;57(16):1825-34. doi: 10.1002/glia.20894. PMID: 19455715.

23. Wang L, Lee HK, Seo IA, Shin YK, Lee KY, Park HT. Cell type-specific STAT3 activation by gp130-related cytokines in the peripheral nerves. Neuroreport. 2009 May 6;20(7):663-8. doi: 10.1097/WNR.0b013e32832a09f8. PMID: 19349921.

22. Lee HK, Seo IA, Shin YK, Park JW, Suh DJ, Park HT. Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress. Biochem Biophys Res Commun. 2009 May 1;382(2):445-50. doi: 10.1016/j.bbrc.2009.03.046. Epub 2009 Mar 13. PMID: 19285962.

21. Lee HK, Wang L, Shin YK, Lee KY, Suh DJ, Park HT. Interleukin-6 induces proinflammatory signaling in Schwann cells: a high-throughput analysis. Biochem Biophys Res Commun. 2009 May 1;382(2):410-4. doi: 10.1016/j.bbrc.2009.03.034. Epub 2009 Mar 11. PMID: 19285039.

20. Lee HK, Seo IA, Suh DJ, Hong JI, Yoo YH, Park HT. Interleukin-6 is required for the early induction of glial fibrillary acidic protein in Schwann cells during Wallerian degeneration. J Neurochem. 2009 Feb;108(3):776-86. doi: 10.1111/j.1471-4159.2008.05826.x. PMID: 19187095.

< 2008 >

19. Lee HK, Seo IA, Suh DJ, Lee HJ, Park HT. A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells. J Neurochem. 2009 Jan;108(1):273-84. doi: 10.1111/j.1471-4159.2008.05764.x. Epub 2008 Nov 21. PMID: 19012752.

18. Lee HK, Seo IA, Lee SH, Seo SY, Kim KS, Park HT. Tyrphostin ErbB2 Inhibitors AG825 and AG879 Have Non-specific Suppressive Effects on gp130/ STAT3 Signaling. Korean J Physiol Pharmacol. 2008 Oct;12(5):281-6. doi: 10.4196/kjpp.2008.12.5.281. Epub 2008 Oct 31. PMID: 19967068; PMCID: PMC2788648.

17. Lee HK, Seo IA, Shin YK, Lee SH, Seo SY, Suh DJ, Park HT. Netrin-1 specifically enhances cell spreading on fibronectin in human glioblastoma cells. Korean J Physiol Pharmacol. 2008 Oct;12(5):225-30. doi: 10.4196/kjpp.2008.12.5.225. Epub 2008 Oct 31. PMID: 19967060; PMCID: PMC2788640.

< 2007 >

16. Wang L, Lee KY, Park HT, Kang DS. Expression profile of tumor endothelial marker 7 and a putative ligand in the rat spinal cord and dorsal root ganglion. Asian Spine J. 2007 Dec;1(2):65-74. doi: 10.4184/asj.2007.1.2.65. Epub 2007 Dec 31. PMID: 20411127; PMCID: PMC2857480.

15. Lee HK, Seo IA, Seo E, Seo SY, Lee HJ, Park HT. Netrin-1 induces proliferation of Schwann cells through Unc5b receptor. Biochem Biophys Res Commun. 2007 Nov 3;362(4):1057-62. doi: 10.1016/j.bbrc.2007.08.143. Epub 2007 Aug 31. PMID: 17825258.

14. Park JI, Seo IA, Lee HK, Park HT, Shin SW, Park YM, Ahn KJ. Netrin inhibits regenerative axon growth of adult dorsal root ganglion neurons in vitro. J Korean Med Sci. 2007 Aug;22(4):641-5. doi: 10.3346/jkms.2007.22.4.641. PMID: 17728502; PMCID: PMC2693812.

13. Ahn KJ, Seo IA, Lee HK, Choi EJ, Seo EH, Lee HJ, Park HT. Down-regulation of UNC5 homologue expression after the spinal cord injury in the adult rat. Neurosci Lett. 2007 May 23;419(1):43-8. doi: 10.1016/j.neulet.2007.03.068. Epub 2007 Apr 11. PMID: 17452076.

12. Lee HK, Seo IA, Park HK, Park YM, Ahn KJ, Yoo YH, Park HT. Nidogen is a prosurvival and promigratory factor for adult Schwann cells. J Neurochem. 2007 Aug;102(3):686-98. doi: 10.1111/j.1471-4159.2007.04580.x. Epub 2007 Apr 16. PMID: 17437540.

< 2006 >

11. Yee SB, Baek SJ, Park HT, Jeong SH, Jeong JH, Kim TH, Kim JM, Jeong BK, Park BS, Kwon TK, Yoon I, Yoo YH. zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells. Exp Mol Med. 2006 Dec 31;38(6):634-42. doi: 10.1038/emm.2006.75. PMID: 17202839.

10. Lee SW, Choi SM, Chang YS, Kim KT, Kim TH, Park HT, Park BS, Sohn YJ, Park SK, Cho SH, Chung WT, Yoo YH. A purified extract from Clematis mandshurica prevents staurosporin-induced downregulation of 14-3-3 and subsequent apoptosis on rat chondrocytes. J Ethnopharmacol. 2007 May 4;111(2):213-8. doi: 10.1016/j.jep.2006.11.012. Epub 2006 Nov 21. PMID: 17174496.

9. Lee HK, Kang DS, Seo IA, Choi EJ, Park HT, Park JI. Expression of tumor endothelial marker 7 mRNA and protein in the dorsal root ganglion neurons of the rat. Neurosci Lett. 2006 Jul 10;402(1-2):71-5. doi: 10.1016/j.neulet.2006.04.033. Epub 2006 May 16. PMID: 16707219.

8. Lee HK, Seo IA, Park HK, Park HT. Identification of the basement membrane protein nidogen as a candidate ligand for tumor endothelial marker 7 in vitro and in vivo. FEBS Lett. 2006 Apr 17;580(9):2253-7. doi: 10.1016/j.febslet.2006.03.033. Epub 2006 Mar 20. PMID: 16574105.

< 2005 >

7. Kim TH, Lee HK, Seo IA, Bae HR, Suh DJ, Wu J, Rao Y, Hwang KG, Park HT. Netrin induces down-regulation of its receptor, Deleted in Colorectal Cancer, through the ubiquitin-proteasome pathway in the embryonic cortical neuron. J Neurochem. 2005 Oct;95(1):1-8. doi: 10.1111/j.1471-4159.2005.03314.x. PMID: 16181408; PMCID: PMC2683579.

6. Lee HK, Bae HR, Park HK, Seo IA, Lee EY, Suh DJ, Park HT. Cloning, characterization and neuronal expression profiles of tumor endothelial marker 7 in the rat brain. Brain Res Mol Brain Res. 2005 May 20;136(1-2):189-98. doi:10.1016/j.molbrainres.2005.02.010. PMID: 15893603.

< 2004 >

5. Kang DY, Park JI, Cho WS, Jeong MH, Cho GW, Park HT, Bae HR. Identification of vasopressin-induced genes in AQP2-transfected MDCK cells by suppression subtractive hybridization. Biochem Biophys Res Commun. 2004 Nov 26;324(4):1234-41. doi: 10.1016/j.bbrc.2004.09.185. PMID: 15504347.

4. Jeong MH, Jin YH, Kang EY, Jo WS, Park HT, Lee JD, Yoo YJ, Jeong SJ. The modulation of radiation-induced cell death by genistein in K562 cells: activation of thymidine kinase 1. Cell Res. 2004 Aug;14(4):295-302. doi: 10.1038/sj.cr.7290230. PMID: 15353126.                                                             .                                 

< 2003 >

3. Park SK, Park JH, Kwon YC, Kim HS, Yoon MS, Park HT. The effect of combined aerobic and resistance exercise training on abdominal fat in obese middle-aged women. J Physiol Anthropol Appl Human Sci. 2003 May;22(3):129-35. PubMed PMID:12808225.                                                                                                                .                                 

< 2001 >

2. Lee MJ, Oh JY, Park HT, Uhlinger DJ, Kwak JY. Enhancement of phospholipase D activity by overexpression of amyloid precursor protein in P19 mouse embryonic carcinoma cells. Neurosci Lett. 2001 Nov 27;315(3):159-63. PubMed PMID: 11716987.                                                 . 

< 2000 >

1. Lee SA, Park JK, Kang EK, Bae HR, Bae KW, Park HT. Calmodulin-dependent activation of p38 and p42/44 mitogen-activated protein kinases contributes to c-fos expression by calcium in PC12 cells: modulation by nitric oxide. Brain Res Mol Brain Res. 2000 Jan 10;75(1):16-24. PubMed PMID: 10648884                                                                                                                                                                                .