LEXINGTON, Mass. and EDINBURGH, UK—July 5, 2017—
Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.
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EDINBURGH, UK and GRANADA, Spain—July 21, 2017—
Researchers at the Centre for Genomics and Oncological Research (GENYO) located in Granada, Spain, in collaboration with DestiNA have developed a novel assay for the diagnosis and monitoring of Trypanosomatids. The method is based on a single-plex PCR, using specific primers that amplify a conserved homology region of Trypanosomatidae species. Amplified fragments are analyzed by DestiNA technology using two DestiNA probes and the four SMART nucleobases with MALDI-ToF for the unique pattern of ‘Single Nucleotide Fingerprints’ (SNF) for each species. This molecular assay can unequivocally identify the trypanosomiasis specie presents in a sample through their unique SNF pattern. The novel assay has been published in the peer-reviewed scientific journal Talanta.
DestiNA has adapted this MALDI-ToF based molecular assay to a colorimetric-based system using low density arrays within a spin-tube. This product provides an easy-to-use and cost effective tool with high sensitivity and specificity. The novel kit permits a rapid identification and differential diagnosis of Chagas disease and Leishmaniasis and monitoring therapeutic responses. For more information regarding this product, please see this page.
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