Articles

Second-Generation AUTACs for Targeted Autophagic Degradation 

Daiki Takahashi, Taiichi Ora, Shigekazu Sasaki, Naoki Ishii, Toshio Tanaka, Takumi Matsuda, Mutsuki Ikeda, Jun Moriyama, Nobuo Cho, Hiroshi Nara, Hironobu Maezaki, Masahiro Kamaura, Kenichiro Shimokawa, and Hirokazu Arimoto.

Journal of Medicinal Chemistry, 2023, 66, 12342-12372.

C. elegans ATG-5 mutants associated with ataxia. 

Azusa Yugeta, Hiroki Arai, Daiki Takahashi, Nami Haruta, Asako Sugimoto, and Hirokazu Arimoto.

microPublication biology, 2023.

p62 Phase-Separation as the Foundation of Autophagy-Based Degraders 

Daiki Takahashi and Hirokazu Arimoto.

Biochemistry,2022, 62, 559-560.

Selective autophagy as the basis of autophagy-based degraders 

Daiki Takahashi and Hirokazu Arimoto.

Cell Chemical Biology, 2021, 28(7), 1061-1071.

Carbamate as an accelerating group in intermolecular Pauson-Khand reaction 

Shota Asano, Kaori Itto-Nakama, and Hirokazu Arimoto.

Tetrahedron Letters,2020, 61(24), 151974.

Targeting selective autophagy by AUTAC degraders 

Daiki Takahashi and Hirokazu Arimoto.

Autophagy, 2020, 16(4), 765-766.

AUTACs: Cargo-Specific Degraders Using Selective Autophagy. 

Daiki Takahashi, Jun Moriyama, Tomoe Nakamura, Erika Miki, Eriko Takahashi, Ayami Sato, Takaaki Akaike, Kaori Itto-Nakama, and Hirokazu Arimoto.

Molecular Cell, 2019, 76(5), 797-810.

Deciphering the mode of action of cell wall-inhibiting antibiotics using metabolic labeling of growing peptidoglycan in Streptococcus pyogenes 

Atsushi Sugimoto, Asuka Maeda, Kaori Itto, and Hirokazu Arimoto.

Scientific Reports, 2017, 7(1), 1129.

Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes 

Shiou-Ling Lu, Tsuyoshi Kawabata, Yi-Lin Cheng, Hiroko Omori, Maho Hamasaki, Tatsuya Kusaba, Ryo Iwamoto, Hirokazu Arimoto, Takeshi Noda, Yee-Shin Lin, and Tamotsu Yoshimori.

PLoS Pathogens, 2017, 13(7).

8-Nitro-cGMP: A novel protein-reactive cNMP and its emerging roles in autophagy 

Hirokazu Arimoto and Daiki Takahashi.

Handbook of Experimental Pharmacology, 2017,  238, 253-268.

Novel blood-brain barrier-permeable spin probe for in vivo electron paramagnetic resonance imaging 

Xiaolei Wang, Miho Emoto, Yusuke Miyake, Kaori Itto, Shu Xu, Hirotada Fujii, Hiroshi Hirata, and Hirokazu Arimoto.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26(20), 4947-4949.

Strategies for construction of the all-carbon macrocyclic skeleton of the ansamycin antibiotic-kendomycin 

Shu Xu and Hirokazu Arimoto.

JOURNAL OF ANTIBIOTICS, 2016, 69(4), 203-212.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 

Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M. Adams, Peter D. Adams, Khosrow Adeli, et al.

Autophagy, 2016, 12(2), 443.

Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance 

Hiroki Kinouchi, Hirokazu Arimoto, Kenzo Nishiguchi, Masako Oka, Hideki Maki, Hiroshi Kitagawa, and Hiroshi Kamimori.

Biological and Pharmaceutical Bulletin, 2014, 37(8), 1383-1389.

Binding properties of antimicrobial agents to dipeptide terminal of lipid II using surface plasmon resonance 

Hiroki Kinouchi, Hirokazu Arimoto, Kenzo Nishiguchi, Masako Oka, Hideki Maki, Hiroshi Kitagawa, and Hiroshi Kamimori.

ANALYTICAL BIOCHEMISTRY, 2014, 452, 67-75.

Total Synthesis of the Antibiotic Kendomycin: A Macrocyclization Using the Tsuji-Trost Etherification 

Tetsuya Sengoku, Shu Xu, Kenji Ogura, Yoshinori Emori, Kenji Kitada, Daisuke Uemura, and Hirokazu Arimoto.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53(16), 4213-4216.

Synthesis of 15N-labeled 4-oxo-2,2,6,6-tetraethylpiperidine nitroxide for EPR brain imaging 

Xiaolei Wang, Miho Emoto, Atsushi Sugimoto, Yusuke Miyake, Kaori Itto, Mitsuo Amasaka, Shu Xu, Hiroshi Hirata, Hirotada Fujii, and Hirokazu Arimoto.

Tetrahedron Letters, 2014, 55(13), 2146-2149.

Enantioselective Total Synthesis of Pinnaic Acid and Halichlorine 

Shu Xu, Daisuke Unabara, Daisuke Uemura, and Hirokazu Arimoto.

CHEMISTRY-AN ASIAN JOURNAL, 2014, 9(1), 367-375.

Unexpected dehomologation of primary alcohols to one-carbon shorter carboxylic acids using o-iodoxybenzoic acid (IBX) 

Shu Xu, Kaori Itto, Masahide Satoh, and Hirokazu Arimoto.

CHEMICAL COMMUNICATIONS, 2014, 50(21), 2758-2761.

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