Significant Outcomes of Research Projects:
Under the Maize-Spodoptera project, I have explored the molecular mechanism behind maize tolerance against S. litura, using a microarray-based genome wide expression analysis. Applying this natural phenomenon of the integrated approach of defense and tolerance in integrated pest management will be a superior insect pest management strategy.
Under the AKR1C1 project, we have identified compounds that may be exploited in hit-to-lead development for treatment of breast, endometrial and cervical cancer. Though the current study focused on the role of AKR1C1 as an emerging cancer target, other functions of this enzyme (both catalytic and non-catalytic) are also becoming evident, including the role of AKR1C1 in pre-term birth.
Under the innovation project “The impact of lifestyle change during adolescence on lifestyle chronic Diseases”, I was able to assess the major factors that lead to chronic diseases in adolescents. This study helped us to establish smoking and alcohol consumption emerged as major contributors to disease burden among adolescents.
Designed a computational tool - NeuroPIpred that can predict, design and scan insect neuropeptides. Insect neuropeptides can act as potential targets for pest control.
Published several research papers, book chapters and edited four books, including ‘Molecular aspects of plant-pathogen interaction’’ and ‘Plant-Pest Interactions: From Molecular Mechanisms to Chemical Ecology’ by Springer-Nature.