Research Publications

2027

55. Malpani, P.; Bhatt, S.; Mehta, A.; Bhuvanesh, N.; Joshi, H.; Sharma, A. K.* “Targeting Cu2+ mediated Aβ Aggregation and ROS Generation Using 4-aminophenylbenzothiazole–Based Chelators” Inorganica Chimica Acta 605 (2027) 123496. https://doi.org/10.1016/j.ica.2026.123496 .

2026

54. Khan, T. A.; Yadav, A.; Malpani, P.; Bhar, K.; Kumar, V.;* Sharma, A. K.* “Variation of Arene Moiety in Ruthenium(II)-Arene Halido Complexes of Quinoline and Benzazole Derived Ligands: Development and Anti-Prostate Cancer Potential” Chemistry – An Asian Journal, 2026; 21:e70946. https://doi.org/10.1002/asia.70946

Publications before joining University of Hyderabad

53. Malpani, P.; Rana, M.; Morda, U.; Sharma, A. K.* “Flavonoids: Morin and Rutin, Evaluated for their Anti-Alzheimer’s Potential: Metal Chelation, Amyloid Inhibition and Cholinesterase Activity” ChemistrySelect, 2026, 11:e04275. https://doi.org/10.1002/slct.202504275  

52. Kumar, V.; Yadav, A.; Chauhan, N. P. S.; Malpani, P.; Agnihotri, N.; Sharma, A. K.* Kumar, V.* “Controlling Stemness in 2D and 3D Models of Triple-Negative Breast Cancer Using a Ruthenium(II) Arene Complex” ChemistrySelect, 2026, 11:e04410. https://doi.org/10.1002/slct.202504410   

2025

51. Mahala, S.; Shehawat, M.; Singh, S.; Bhuvnesh, N.; Sharma, A. K.; Joshi, H.;*  “Manganese(I) Pincer Complexes as Catalysts for Dehydrogenative Annulation: Direct Access to Biologically Relevant Heterocycles from Alcohols and 2'-Aminoacetophenones” Organometallics, 2025, 44, 23, 2763–2776. (Impact factor, 2.9) https://doi.org/10.1021/acs.organomet.5c00370. Publication Date: 16 Nov. 2025

50. Bandi, S.; Rathnayaka, R.M.M.; Rana, M.; Sangalkar, A. A.; Pawar, R.; Fawaz, G.; Gahunia, E.; Courtemanche, A.; Boligorla, A.; Pawar, R.; Sharma, A. K.* Gadde, S.; D’Souza, F.; Chitta, R. “Unveiling the Light Induced Energy Transfer Events in Water Soluble Benzothiazole Appended Borondipyrromethene: Synthesis, Photophysical Study, and Applications to Amyloid Binding” Chemistry-An Asian Journal, 2025, e70372. (Impact factor, 3.5). Publication Date: 13 October 2025.

49. Mahala, S.; Rakesh, P.; Singh, S.; Sharma, A. K. Joshi, H.;* “Mn(I)-NNSe Pincer Complex Catalyzed Regioselective Synthesis of Bisindolylmethanes under Base and Solvent-free Conditions” Asian Journal of Organic Chemistry, 2025, e00323. [https://doi.org/ 10.1002/ajoc.202500323] Publication Date: 23 May 2025. (Impact factor, 2.8)

48. Khan, T. A.; Yadav, A.; Kumar, V.;* Sharma, A. K.* “Development of 2-bis(quinolin-2-ylmethylene)hydrazine based half-sandwich ruthenium(II) arene complexes with high cytotoxicity in castration-resistant prostate cancer cells” European Journal of Inorganic Chemistry, 2025, e202400851. [Impact factor = 2.2] Publication Date: 18 March 2025. (Impact factor, 2.2)

2024

47. Bhatt, S.; Malpani, P.; Swornaprava Pati, S.; Kumar N.; Bhuvnesh, N.; Joshi, H.* and Sharma, A. K.* “Ruthenium Complexes of Phenylbenzothiazole-Quinoline based Ligands for Selective α-Olefination of Methylazaarenes” European Journal of Inorganic Chemistry, 2024, e202400623. Publication Date: 28 October 2024.  (Impact factor, 2.2)

46. Rana, M.; Terpstra, K.; Gutierrez, C.; Xu, K.; Arya, H.; Bhatt, T. K.; Mirica, L. M.;* Sharma, A. K.* “Evaluation of Anti-Alzheimer’s Potential of Azo-Stilbene-Thioflavin-T derived Multifunctional Molecules: Synthesis, Metal and Ab Species Binding and Cholinesterase Activity” Chemistry A European Journal, 2024, e202402748. Publication Date: 30 October 2024. (Impact factor, 3.9) Preprint available at: ChemRXiv 2024. 0.26434/chemrxiv-2024-7357m (link:  https://chemrxiv.org/engage/chemrxiv/article-details/66de90c151558a15ef7a8e80

45. Rana, M.; Raj M. V. N.; Sharma, A. K.* “Selected Examples of Iron and Cobalt Complexes Exhibiting Spin-Crossover Behavior” Book Chapter in “Advances in materials science: Fundamentals and applications” Editors: R. S. Ningthoujam and A. K. Tyagi, Book in Springer Nature. 2024, pp 389–426 ISBN: 978-981-97-4645-3. [https://link.springer.com/chapter/10.1007/978-981-97-4646-0_12#citeas]. First Online: 16 August 2024. 

44. Khan, T. A.; Bhar, K.; Bhatt, S.; Kumar, V.; Kumari R.; Sharma, A. K.* “Bis-quinoline Ruthenium(II) arene complexes with submicromolar cytotoxicity in castration-resistant prostate cancer cells” Chem. Commun., 2024, 60, 1579. [Impact factor = 4.569]  Publication Date: 21 Dec 2023. (Impact factor, 4.3)

2023

43. Sunda, A.;* Sharma, A. K.* “Molecular Insights of Cu/Zn Metal response to the Amyloid β-peptide (1-42)” ACS Physical Chemistry Au, 2023, 4(1), 57-66. [Impact factor = NA]  Publication Date: October 25, 2023. (Impact factor, 3.7)

42. Kumar, V.; Rana, M.; Sharma, A. K.*; Sinha, S.; Ajajuddin; Gupta Umesh,* “Vitamin-C decorated PEGylated PAMAM dendrimers for effective inhibition of amyloid aggregation and improved In vivo pharmacokinetics” Journal of Drug Delivery Science and Technology, 2023, 89, 105058. [Impact factor = 5.062] Publication Date: Nov. 2023. (Impact factor, 4.5)

41. Bhatt, S.; Rana, M.; Sharma, A. K.* Joshi, H.* “Ruthenium Complexes of Bidentate N,N-Ligand as Catalyst for Efficient and Selective N-alkylation of Amines with Alcohols” Asian Journal of Organic Chemistry, 2023, 12(6) e202300158. [Impact factor = 3.116] Publication Date: 16 May 2023. (Impact factor, 2.8)

2022

40. Bhatt, S.; Meena, N.; Kumar, M.; Bhuvanesh, N.; Kumar, A.; Sharma, A. K.* Joshi, H.* “Design and Syntheses of Ruthenium ENE (E = S, Se) Pincer Complexes: A Versatile System for Catalytic and Biological Applications” Chemistry-An Asian Journal, 2022, 17(21). E202200736. [DOI: 10.1002/asia.202200736] Publication Date: September 2022. [Impact factor = 4.569] Publication Date: 05 September 2022. (Impact factor, 3.5)

39. Rana, M.; Cho, H.J.; Arya, H.; Bhatt, T. K.; Bhar, K.; Mirica, L. M.; Sharma, A. K.* “Azo-Stilbene and Pyridine-Amine Hybrid Multifunctional Molecules to Target Metal Mediated Neurotoxicity and Amyloid-β Aggregation in Alzheimer’s disease” Inorg. Chem. 2022, 61, 10294-10309. [DOI: 10.1021/acs.inorgchem.2c00502] Publication Date: June 29, 2022. [Impact factor = 5.436] (Impact factor, 3.5)

38. Bhar, K.; Guo, W.; Gonidec, M.; Raj M, V. N. R.; Bhatt, S.; Perdih, F.; Guionneau, P.;* Chastnet, G.;* Sharma, A. K.;* “High temperature spin crossover behaviour of mononuclear bis-(thiocyanato)iron(II) complexes with judiciously designed bidentate N-donor Schiff bases with varying substituent ” Dalton Trans. 2022, 51, 9302-9313. [DOI: 10.1039/D2DT00416J]  (Impact factor, 3.5)4.569] Publication Date: 24 May 2022

2020

37. Sun, L.; Sharma, A. K.; Han, B.-H.; Mirica, L. M.;* “Amentoflavone: A Bifunctional Metal Chelator that Controls the Formation of Neurotoxic Soluble Aβ42 Oligomers” ACS Chemical Neurosciences, 2020, 11, 17, 2741-2752 [doi/10.1021/acschemneuro.0c00376]. Publication Date: August 5, 2020. [Impact factor = 5.78]

36. Rana, M.; Pareek, A.; Bhardwaj, S.; Arya, G.; Nimesh, S.; Arya, H.; Bhatt, T.; Yaragorala, S.;* Sharma, A. K.* “Aryldiazoquinoline based Multifunctional Small Molecules for Controlling AChE Activity and Modulation of Aβ Aggregation related to Alzheimer’s Disease” RSC Advances, 2020, 10, 28827-28837. Publication Date: 04 Aug 2020. [Impact factor = 4.036]

35. Jain, S.; Bhar, K.; Bandyopadhyaya, S.; Singh, V. K.; Mandal, C. C.; Tapryal, S.; Sharma, A. K.* “Development, Evaluation and Effect of Anionic Co-ligand on the Biological Activity of Benzothiazole Derived Copper(II) Complexes” Journal of Inorganic Biochemistry, 2020, 210, 111174. [https://doi.org/10.1016/j.jinorgbio.2020.111174] Publication Date: 3 July 2020. [Impact factor = 4.155]

34. Cho, H.-J.; Sharma, A. K.; Zhang, Y.; Gross, M. L.; Mirica, L. M.;* “A Multifunctional Chemical Agent as an Attenuator of Amyloid Burden and Neuroinflammation in Alzheimer’s Disease” ACS Chemical Neurosciences, 2020, 11, 10, 1471-1481 [doi/10.1021/acschemneuro.0c00114]. Publication Date: April 20, 2020. [Impact factor = 5.78]

33. Jain, S.; Bhar, K.; Kumar, S.; Bandyopadhyaya, S.; Tapryal, S.; Mandal, C. C.; Sharma, A. K.* “Homo- and Heteroleptic trimethoxy terpyridine-Cu(II) complexes: Synthesis, Characterization, DNA/BSA Binding, DNA Cleavage and Cytotoxicity Studies” Dalton Trans. 2020, 49, 4100-4113. Publication Date: 27 Feb 2020. [Impact factor = 4.569]

32. Rajput, A.; Sharma, A. K.; Barman, S. K.; Saha, A.; Mukherjee, R.*, “Valence tautomerism and delocalization in transition metal complexes of o-aminophenolates and other redox-active ligands. Some recent results” Coord. Chem. Rev. 2020, 414, 213240 [doi.org/10.1016/j.ccr.2020.213240].   Publication Date: 16 March 2020. [Impact factor = 24.83]

31. Khan, T. A.; Bhar, K.; Thirumoorthi, R.; Roy, T. K.; Sharma, A. K.* “Design, Synthesis, Characterization and Evaluation of Anticancer Activity of Water-Soluble Half-sandwich Ruthenium (II) Arene Halido Complexes” New Journal of Chemistry, 2020, 44, 239-257. [doi.org/10.1039/C9NJ03663F] Publication Date: 18 Nov 2019.  [Impact factor = 3.925]

2019

30. Raj M. V. N.; Bhar, K.; Khan, T. A.; Jain, S.; Perdih, F.; Mitra, P.; Sharma, A. K.* “Temperature induced spin crossover behaviour in mononuclear cobalt(II) bis terpyridine complexes” MRS Advances, 2019, 4 (28-29), 1597-1610. Publication Date: 08 April 2019. [DOI: https://doi.org/10.1557/adv.2019.166] [Impact factor = 0.84]

29. Raj M. V. N.; Bhar, K.; Jain, S.; Rana, M.; Khan, T. A.; Sharma, A. K.* “Syntheses, X-ray structures, electrochemical properties and biological evaluation of mono- and di-nuclear N2O2-donor ligand-Fe systems” Transition Metal Chemistry, 2019, 44(7), 615-626. Publication Date: 15 April 2019. [Impact factor = 2.266]

28. Singh, A. K.; Gothwal, A.; Rani, S.; Rana, M.; Sharma, A. K. Yadav, A. K.; Gupta, U.* “Dendrimer Donepezil Conjugates for Improved Brain Delivery and Better in vivo Pharmacokinetics” ACS Omega, 2019, 4, 4519-4529. Publication Date: March 1, 2019. [Impact factor = 4.132]

27. Sheoran, M.; Bhar, K.; Jain, S.; Rana, M.; Khan, T. A.; Sharma, A. K.* “Phenoxo-bridged dicopper complexes: Syntheses, characterizations, crystal structures and catecholase activity” Polyhedron, 2019, 161, 169-178. Publication Date: January 14, 2019.  [Impact factor = 3.052]

26. Rana, M.; Sharma, A. K.* “Cu and Zn Interactions with Aβ peptides: Consequence of Coordination on Aggregation and Formation of Neurotoxic Soluble Aβ Oligomers” Metallomics, 2019, 11, 64-84. [DOI: 10.1039/c8mt00203g] Publication Date: 14 September 2018. [Impact factor = 3.4]

2018

25. Rajput, A.; Sharma, A. K.; Barman, S. K.; Lloret, F.; Mukherjee, R.*, Six-coordinate [CoIII(L)2]z (z = 1−, 0, 1+) complexes of an azo-appended o-aminophenolate in amidate (2−) and iminosemiquinonate π-radical (1−) redoxlevels: the existence of valence-tautomerism”, Dalton Trans. 2018, 47, 17086-17101. Publication Date: Nov. 2, 2018. [Impact factor = 4.569]

24. Sheoran, M.; Bhar, K.; Khan, T. A.; Naik, S. G.; Sharma, A. K.*, “Synthesis and characterization of phenoxo-bridged dinuclear zinc(II) halide complexes: Role of electron withdrawing group onphosphatase activity” Journal of Chemical Science, 2018, 130, 108.  Publication Date: 27 July 2018. [Impact factor = 1.573]

23. Pandey, P; Sharma, A.; Rani, S; Mishra, G.; Gopal, K.; Patra, A.; Rana, M.; Sharma, A. K.; Yadav, A.; Gupta, U.* “MCM-41 Nanoparticles for Brain Delivery: Better Choline-Esterase and Amyloid Formation Inhibition with Improved Kinetics”, ACS Biomaterials Science & Engineering, 2018, 4(8), 2860-2869. Publication Date: July 9, 2018. [Impact factor = 5.395]

22. Rana, M.; Cho, H.-J.; Roy, T. K.; Mirica, L. M.; Sharma, A. K.* “Azo-dyes based small bifunctional molecules for metal chelation and controlling amyloid formation”, Inorg. Chim. Acta, 2018, 471, 419-429. Publication Date: 22 November 2017. [Impact factor = 2.545]

2017

21. Sharma, A. K.; Schultz, J. W.; Prior, J. T.; Rath, N. P.; Mirica, L. M.* “Coordination Chemistry of Bifunctional Chemical Agents Designed for Applications in 64Cu PET Imaging for Alzheimer’s Disease”, Inorg. Chem. 2017, 56, 13801-13814. Publication Date: Nov. 7, 2017. [Impact factor = 5.436]

20. Bandara, N.; Sharma, A. K.; Krieger, S.; Schultz, J. W.; Han, B.-H.; Rogers, B. E.; Mirica, L. M.* “Evaluation of 64Cu-based Radiopharmaceuticals that Target Aβ Peptide Aggregates as Diagnostic Tools for Alzheimer’s Disease” J. Am. Chem. Soc. 2017, 139(36), 12550-12558. Publication Date: August 21, 2017. [Impact factor = 16.38]

19. Sheoran, M.; Bhar, K.; Sharma, A. K.; Naik, S. G.* “Phosphatase activity and DNA binding studies of dinuclearphenoxo-bridged zinc(II) complexes with N,N,O-donor ligand and halide ions of rare cis-configuration”, Polyhedron, 2017, 129, 82-91. Publication Date: 30 March 2017. [Impact factor = 3.052]

18. US Patent “Metal-binding bifunctional compounds as diagnostic agents for alzheimer's disease” Mirica, L. M.; Sharma, A. K.; Schultz, J.; Publication date: 2015-07-30, US Patent. Patent Publication Number: US20150209452 A1; Application No. US 14/606,714. Publication Date: Nov. 7, 2017.  

2016

17. Yaragorla, S.* Dada, R.; Singh, G.; Pareek, A.; Rana M.; Sharma, A. K. “Ca(II)-Catalyzed regioselective cascade synthesis of Oxindolyl naphthofurans through Meyer-Schuster type Rearrangement” Chemistry Select 2016, 1(21), 6902-6906. Publication Date: 27 December 2016. [Impact factor = 2.307]

16. Bera, S.; Lamba, S.; Rashid, M.; Sharma, A. K.; Medvinsky, A. B.; Li, B.-L.; Chakraborty, A.* “Robust kinetic regulation of ammonium assimilation by glutamate dehydrogenase” Integrative Biology, 2016, 8(11), 1126-1132. Publication Date: 17 October 2016. [Impact factor = 3.177]

15. Pareek, A.; Dada, R.; Rana M.; Sharma, A. K.; Yaragorla, S.* “Bu4NPF6 promoted regioselective cascade synthesis of functionally embellished naphthofurans under acid, metal & solvent free conditions” RSC Advances, 2016, 6, 89732-89743. Publication Date: 13 Sep 2016. [Impact factor = 4.036]

14. Badgurjar, D.; Sudhakar, K.; Jain, K.; Kalantri, V.; Venkatesh, Y.; Duvva, N.; Prasanthkumar, S.; Sharma, A. K.;* Bangal, P. R.;* Chitta, R.;* Giribabu. L.* “Ultrafast Intramolecular Photo-induced Energy Transfer Events in Benzothiazole –Borondipyrromethene Donor – Acceptor Dyads” J. Phys. Chem. C. 2016, 120, 16305-16321. Publication Date: July 8, 2016. [Impact factor = 4.177]

Publications before joining CURAJ [from Ph.D. and Post-Doc. Work]

2014

13. Sharma, A. K.; Kim, J.; Hawco, N. J.; Rath, N. P.; Kim, J.; Mirica, L. M.* “Small Bifunctional Chelators that Do Not Dissagregate Amyloid Fibrils Show Reduced Cellular Toxicity”, Inorg. Chem. 2014, 53, 11367-11376. Publication Date: 21 October 2014.

12. Mishra, V.; Sharma, A. K.; Mukherjee, R.* “Formation of 1D-Chain via C–H...Cl Interaction Utilizing [(L3)ZnIICl2] (L3 = 2-[3-(20-Pyridyl)pyrazol-1-ylmethyl]-(1-methylimidazole)) Tecton”, Proc. Natl. Acad. Sci., India, Sect. A Phys. Sci. 2014, 84(2), 315-320. Publication Date: 22 March 2014.

11. Rajput, A.; Sharma. A. K.; Barman, S.; Koley, S.; Mukherjee, R.* “Neutral, Cationic, and Anionic Low-Spin Iron(III) Complexes Stabilized by Amidophenolate and Iminobenzosemiquinonate Radical in N,N,O Ligands”, Inorg. Chem. 2014, 53, 36-48. Publication Date: 10 December 2013. [https://doi.org/10.1021/ic401985d]

2013

10. Zhang, Y.; Rempel, D. L.; Zhang, J.; Sharma, A. K.; Gross, M. L.; Mirica, L. M.* “Pulsed Hydrogen/Deuterium Exchange Mass Spectrometry Probes Conformational Changes in Amyloid Beta (Aβ) Aggregation”, Proc. Natl. Acad. Sci. U.S.A., 2013, 110(26), 10604-10609. Publication Date: 23 July 2013.

9. Sharma, A. K.; Pavlova, S. T.; Kim, J.; Kim, J.; Mirica, L. M.* “The Effect of Cu2+ and Zn2+ on the Aβ42 Peptide Aggregation and Cellular Toxicity”, Metallomics 2013, 5, 1529-1536. Publication Date: 23 August 2013. [https://doi.org/10.1039/C3MT00161J]

8. Sharma, A. K.; Lloret, F.; Mukherjee, R.* “Phenolate- and Acetate (Both μ2-1,1 and μ2-1,3 Mode)-Bridged Linear CoII3 and CoII2MnII Trimers: Magneto-structural Studies”, Inorg. Chem. 2013, 52, 4825-4833. Publication Date: 11 April 2013. [https://doi.org/10.1021/ic302259t]

2012

7. Sharma, A. K.; Pavlova, S. T.; Kim, J.; Finkelstein, D.; Hawco, N. J.; Rath, N. P.; Kim, J.; Mirica, L. M.* “Bifunctional Compounds for Controlling Metal-Mediated Aggregation of Aβ42 Peptide”, J. Am. Chem. Soc. 2012, 134, 6625-6636. Publication Date: 27 March 2012. [https://doi.org/10.1021/ja210588m]

2011

6. Sharma, A. K.; De, A.; Balamurugan, V.; Mukherjee, R.* “Conformational Flexibility of 2,6-bis(pyrazol-1-ylmethyl)pyridine (L5) in Discrete Complexes [(L5)CoII(H2O)3]Cl2 and [(L5)NiII(H2O)2Cl]Cl·H2O and in a Coordination Polymer [(L5)HgIICl2]·HgCl2: Notable Supramolecular Topologies”, Inorg. Chim. Acta 2011, 372, 327-332. Publication Date: 17 February 2011. [https://doi.org/10.1016/j.ica.2011.02.038]

5. Javed, S.; Balamurugan, V.; Jacob, W.; Sharma, A. K.; Mukherjee, R. N.* “Discrete Monomeric and Chloride-Bridged and 1D Coordination Polymeric Mercury(II) Complexes of a Class of Pyridyl-Pyrazole Ligand with Variable Denticity and Flexibility", Indian J. Chem. Sec. A, 2011, 1248-1256. Publication Date: 21 June 2011.

2010

4. Sharma, A. K.; Biswas, S.; Barman, S. K.; Mukherjee, R.* “Azo-containing Pyridine Amide Ligand. A Six-coordinate Nickel(II) Complex and its One-electron Oxidized Species: Structure and Properties”, Inorg. Chim. Acta 2010, 363, 2720-2727. Publication Date: 27 March 2010. [https://doi.org/10.1016/j.ica.2010.03.056]

2009

3. Sharma, A. K.; De, A.; Mukherjee, R.* “Design, Structure, and Properties of Functional Metal-Ligand Inorganic Modules”, Current Opinion in Solid State and Material Science, 2009, 13, 54-67. [https://doi.org/10.1016/j.cossms.2009.06.001]

2008

2. Sharma, A. K.; Mukherjee, R.* “Synthesis and Properties of (2-pyridyl)alkylamine- and (2-pyridyl)alkylamine-amide-coordinated Copper(II) Complexes. Structures and Noncovalent Interactions”, Inorg. Chim. Acta 2008, 361, 2768-2776.

2007

1. Sharma, A. K.; Lloret, F.; V.; Mukherjee, R.* “Phenolate- and Acetate (both m2-1,1 and m2-1,3 mode)- Bridged Face-Shared Trioctahedral Linear NiII3, NiII2MII (M = Mn, Co) Complexes: Ferro- and Antiferromagnetic Coupling”, Inorg. Chem. 2007, 46, 5128-5130.

Patents:

1.   US Patent “Metal-binding bifunctional compounds as diagnostic agents for alzheimer's disease” Mirica, L. M.; Sharma, A. K.; Schultz, J.; Publication date: 2015-07-30, US Patent. Patent Publication Number: US20150209452 A1; Application No. US 14/606,714. Publication Date: Nov. 7, 2017.  

Publications as Book/Book Chapter

1.   Rana, M.; Raj M. V. N.; Sharma, A. K.* “Selected Examples of Iron and Cobalt Complexes Exhibiting Spin-Crossover Behavior” Book Chapter in “Advances in materials science: Fundamentals and applications” Editors: R. S. Ningthoujam and A. K. Tyagi, Book in Springer Nature. 2024, pp 389–426 [https://link.springer.com/chapter/10.1007/978-981-97-4646-0_12#citeas]. First Online: 16 August 2024.